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[CAS NO. 270249-38-2] (2S)-2'-Methoxykurarinone
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-N1746 |
| Brand: | MCE |
| CAS: | 270249-38-2 |
Overview
| MDL | - |
|---|---|
| Molecular Weight | 452.54 |
| Molecular Formula | C27H32O6 |
| SMILES | O=C1C[C@@H](C2=CC=C(O)C=C2OC)OC3=C(C[C@H](C(C)=C)C/C=C(C)\C)C(O)=CC(OC)=C13 |
Summary
(2S)-2'-Methoxykurarinone, a compound isolated from the roots of Sophora flavescens , has anti-inflammatory, antipyretic, antidiabetic, and antineoplastic effects. (2S)-2'-Methoxykurarinone (MK) inhibits osteoclastogenesis and bone resorption through down-regulation of RANKL signaling. (2S)-2'-Methoxykurarinone (MK) displays cytotoxic activity against human myeloid leukemia HL-60 cells [1] [2] .
Appearance
Solid
Source
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 25 mg/mL ( 55.24 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.2097 mL | 11.0487 mL | 22.0975 mL |
| 5 mM | 0.4419 mL | 2.2097 mL | 4.4195 mL |
| 10 mM | 0.2210 mL | 1.1049 mL | 2.2097 mL |
-
1.
-
2.
Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)
Solubility: 2.5 mg/mL (5.52 mM); Clear solution; Need ultrasonic
References
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