[CAS NO. 2732-18-5] 5,7-Dihydroxycoumarin
PRODUCTS SPECIFICATIONS [2732-18-5]
DESCRIPTION [2732-18-5]
Overview
| MDL | MFCD00488354 |
|---|---|
| Molecular Weight | 178.14 |
| Molecular Formula | C9H6O4 |
| SMILES | O=C1C=CC2=C(C=C(C=C2O)O)O1 |
Summary
5,7-Dihydroxycoumarin is a coumarin isolated from the inflorescences of Macaranga triloba . 5,7-Dihydroxycoumarin has antibacterial activities [1] [2] .
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 25 mg/mL ( 140.34 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 5.6136 mL | 28.0678 mL | 56.1356 mL |
| 5 mM | 1.1227 mL | 5.6136 mL | 11.2271 mL |
| 10 mM | 0.5614 mL | 2.8068 mL | 5.6136 mL |
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1.
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2.
Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)
Solubility: 2.5 mg/mL (14.03 mM); Suspended solution; Need ultrasonic
References
- [1] Ishak Zakaria, et al. Flavonoids with antiplasmodial and cytotoxic activities of Macaranga triloba. Fitoterapia. 2012 Jul;83(5):968-72.
- [2] Yi-Ping Chin, et al. Synthesis and evaluation of antibacterial activities of 5,7-dihydroxycoumarin derivatives. Arch Pharm (Weinheim). 2011 Jun;344(6):386-93.