[CAS NO. 2752-17-2] 2,2-Oxybis(ethylamine)

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PRODUCTS SPECIFICATIONS [2752-17-2]

Catalog

HY-140208

Brand

MCE

CAS

2752-17-2

DESCRIPTION [2752-17-2]

Overview

MDL	MFCD00466591
Molecular Weight	104.15
Molecular Formula	C4H12N2O
SMILES	NCCOCCN

For research use only. We do not sell to patients.

Summary

22-Oxybis(ethylamine) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs ^[1] .

IC50 & Target

PEGs

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Appearance

Liquid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Synonyms

Ethanamine, 2,2′-oxybis-

Ethylamine, 2,2′-oxybis-

2,2′-Oxybis[ethanamine]

Bis(2-aminoethyl) ether

1,5-Diamino-3-oxapentane

2-Aminoethyl ether

3-Oxa-1,5-diaminopentane

2,2′-Oxybis(ethylamine)

2,2′-Oxydi[ethanamine]

Jeffamine EDR 104

3-Oxa-1,5-pentanediamine

2-(2-Aminoethoxy)ethylamine

1,5-Diamine-3-oxapentane

2-(2-Aminoethoxy)ethanamine

EDR 104

2-(2-Aminoethoxy)ethan-1-amine