[CAS NO. 2757763-47-4]  SARS-CoV-2-IN-35

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PRODUCTS SPECIFICATIONS [2757763-47-4]

Catalog
HY-148387
Brand
MCE
CAS
2757763-47-4

DESCRIPTION [2757763-47-4]

Overview

MDL-
Molecular Weight621.67
Molecular FormulaC29H34F3N5O5S
SMILESO=C(C1=NC2=CC=CC=C2S1)[C@H](C[C@H]3C(NCC3)=O)NC([C@@H]4[C@]5([H])[C@@](CN4C([C@H](C(C)C)NC(C(F)(F)F)=O)=O)([H])C5(C)C)=O

For research use only. We do not sell to patients.

Summary

SARS-CoV-2-IN-35 is a potent and orally active SARS-CoV-2 M pro inhibitor with a K i value of 12.1 nM. SARS-CoV-2-IN-35 can be used in research of COVID-19 [1] .


In Vivo

SARS-CoV-2-IN-35 (compound 5; 10 mg/kg; p.o.) has good oral utilization in Wistar-Han rats [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Wistar-Han rats [1]
Dosage: 10 mg/kg
Administration: Oral administration
Result: Had oral F of 33 %.

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.