MDL | - |
---|---|
Molecular Weight | 621.67 |
Molecular Formula | C29H34F3N5O5S |
SMILES | O=C(C1=NC2=CC=CC=C2S1)[C@H](C[C@H]3C(NCC3)=O)NC([C@@H]4[C@]5([H])[C@@](CN4C([C@H](C(C)C)NC(C(F)(F)F)=O)=O)([H])C5(C)C)=O |
SARS-CoV-2-IN-35 is a potent and orally active SARS-CoV-2 M pro inhibitor with a K i value of 12.1 nM. SARS-CoV-2-IN-35 can be used in research of COVID-19 [1] .
SARS-CoV-2-IN-35 (compound 5; 10 mg/kg; p.o.) has good oral utilization in Wistar-Han rats [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Animal Model: | Wistar-Han rats [1] |
Dosage: | 10 mg/kg |
Administration: | Oral administration |
Result: | Had oral F of 33 %. |
Room temperature in continental US; may vary elsewhere.
Please store the product under the recommended conditions in the Certificate of Analysis.