[CAS NO. 2825-00-5] Aureothin
PRODUCTS SPECIFICATIONS [2825-00-5]
DESCRIPTION [2825-00-5]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 397.42 |
| Molecular Formula | C22H23NO6 |
| SMILES | CC1=C([C@H]2C/C(CO2)=C/C(C)=C/C3=CC=C(C=C3)[N+]([O-])=O)OC(OC)=C(C1=O)C |
Summary
IC50 & Target
|
HIV 5.3 nM (IC 50 ) |
In Vitro
Aureothin shows larvicidal activity against A. aegypti with a LC 50 value of 1.5 ppm for 24 h post-treatment, and 3.8 ppm for 48 h post-treatment [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Source
Streptomyces thioluteus
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
References
- [1] Seong Jong Kim, et al. Streptomyces distallicus, a Potential Microbial Biolarvicide. J Agric Food Chem. 2022 Sep 14;70(36):11274-11280.
- [2] Alexander Herrmann, et al. Potent inhibition of HIV replication in primary human cells by novel synthetic polyketides inspired by Aureothin. Sci Rep. 2020 Jan 28;10(1):1326.