[CAS NO. 2825-00-5] Aureothin

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Catalog:	HY-121291
Brand:	MCE
CAS:	2825-00-5

Overview

MDL	-
Molecular Weight	397.42
Molecular Formula	C22H23NO6
SMILES	CC1=C([C@H]2C/C(CO2)=C/C(C)=C/C3=CC=C(C=C3)[N+]([O-])=O)OC(OC)=C(C1=O)C

For research use only. We do not sell to patients.

Summary

Aureothin, is a natural polyketide, is a HIV inhibitor with an IC ₅₀ of 5.3 nM. Aureothin is a microbial biolarvicide ^[1] ^[2] .

IC50 & Target

HIV

5.3 nM (IC ₅₀ )

In Vitro

Aureothin shows larvicidal activity against A. aegypti with a LC ₅₀ value of 1.5 ppm for 24 h post-treatment, and 3.8 ppm for 48 h post-treatment ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Source

Streptomyces thioluteus

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References

[1] Seong Jong Kim, et al. Streptomyces distallicus, a Potential Microbial Biolarvicide. J Agric Food Chem. 2022 Sep 14;70(36):11274-11280.
[2] Alexander Herrmann, et al. Potent inhibition of HIV replication in primary human cells by novel synthetic polyketides inspired by Aureothin. Sci Rep. 2020 Jan 28;10(1):1326.

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