[CAS NO. 2869954-51-6]  Werner syndrome RecQ helicase-IN-2

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PRODUCTS SPECIFICATIONS [2869954-51-6]

Catalog
HY-148700
Brand
MCE
CAS
2869954-51-6

DESCRIPTION [2869954-51-6]

Overview

MDL-
Molecular Weight681.66
Molecular FormulaC32H34F3N9O5
SMILESO=C(N1CCN(CC1)C2=C(CC)N(CC(NC3=CC=C(C(F)(F)F)C=C3C)=O)C4=NC(C5=CCOCC5)=NN4C2=O)C6=NC=NC(C)=C6O

For research use only. We do not sell to patients.

Summary

Werner syndrome RecQ helicase-IN-2 (example 57) is a potent Werner syndrome RecQ DNA helicase enzyme ( WRN ) inhibitor and can be used in cancer research [1] .


In Vitro

Werner syndrome RecQ helicase-IN-2 (example 57) has an IC 50 value of 100 nM for WRN ATPase and GI 50 values of 100 nM and >10 μM for SW48 and DLD1 WRN-KO cell lines, respectively [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Shipping

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.