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[CAS NO. 28718-90-3] DAPI dihydrochloride
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-D0814 |
| Brand: | MCE |
| CAS: | 28718-90-3 |
Overview
| MDL | MFCD00012681 |
|---|---|
| Molecular Weight | 350.25 |
| Molecular Formula | C16H17Cl2N5 |
| SMILES | N=C(C1=CC2=C(C=C1)C=C(C3=CC=C(C(N)=N)C=C3)N2)N.[H]Cl.[H]Cl |
21 Publications Citing Use of MCE
- [1]Cell Res. 2022 Oct 28.
- [2]Light Sci Appl. 2022 Nov 11;11(1):324.
- [3]Adv Funct Mater. 2022: 2204636.
- [4]Autophagy. 2021 Dec 29;1-13.
- [5]J Nucl Med. 2021 Oct 28;jnumed.121.262743.
- [6]Cancer Lett. 2021 Apr 28;504:125-136.
- [7]Acta Biomater. 2019 Sep 15;96:468-479.
- [8]Glia. 2022 Feb;70(2):337-353.
- [9]Mol Nutr Food Res. 2022 Apr;66(7):e2101088.
- [10]Front Cell Dev Biol. 2021 Apr 15;9:665869.
- [11]Acta Pharmacol Sin. 2021 Jul;42(7):1111-1123.
- [12]Front Oncol. 2022 Mar 25;12:773654.
- [13]Phytomedicine. 2020 Mar;68:153146.
- [14]J Ethnopharmacol. 2022 Oct 21;115855.
- [15]Oncotargets Ther. 2020 Oct 6;13:9941-9952.
- [16]J Neuropathol Exp Neurol. 2020 Jul 1;79(7):734-745.
- [17]Acta Biochim Biophys Sin (Shanghai). 2021 Nov 10;53(11):1558-1566.
- [18]Mol Med Rep. 2021 Dec;24(6):832.
- [19]Kaohsiung J Med Sci. 2021 Dec 21.
- [20]Pharmaceuticals. 2022 Jun 6;15(6):721.
- [21]ACS Appl Bio Mater. 2021 Jan 6.
Summary
DAPI dihydrochloride (4',6-diamidino-2-phenylindole) is a fluorescent stain by binding in the minor grove of A-T rich sequences of DNA.
In Vitro
DAPI (4',6-diamidino-2-phenylindole) is a DNA-specific probe which forms a fluorescent complex by attaching in the minor grove of A-T rich sequences of DNA. It also forms nonfluorescent intercalative complexes with double-stranded nucleic acids. DAPI can be used as a DNA-specific probe for flow cytometry, chromosome staining, DNA visualization and quantitation in histochemistry and biochemistry [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 75 mg/mL ( 214.13 mM ; Need ultrasonic)
H 2 O : 5.56 mg/mL ( 15.87 mM ; ultrasonic and warming and heat to 60°C)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.8551 mL | 14.2755 mL | 28.5510 mL |
| 5 mM | 0.5710 mL | 2.8551 mL | 5.7102 mL |
| 10 mM | 0.2855 mL | 1.4276 mL | 2.8551 mL |
Synonyms
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