[CAS NO. 2983-38-2]  Etzadroxil

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PRODUCTS SPECIFICATIONS [2983-38-2]

Catalog
HY-W127442
Brand
MCE
CAS
2983-38-2

DESCRIPTION [2983-38-2]

Overview

MDLMFCD00059396
Molecular Weight144.21
Molecular FormulaC8H16O2
SMILESCCC(CC)C(=O)OCC

For research use only. We do not sell to patients.

Summary

Etzadroxil (Ethyl 2-Ethylbutyrate) is a volatile ester compound. Sulopenem Etzadroxil is an orally available ester prodrug form of Sulopenem, an antibiotic with broad-spectrum activities against Gram-positive and Gram-negative bacteria [1] [2] .


In Vitro

Sulopenem Etzadroxil is an orally available ester prodrug form of sulopenem. After oral administration of sulopenem etzadroxil, the ester bond is cleaved, releasing active Sulopenem [2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Liquid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 693.43 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.9343 mL 34.6717 mL 69.3433 mL
5 mM 1.3869 mL 6.9343 mL 13.8687 mL
10 mM 0.6934 mL 3.4672 mL 6.9343 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (17.34 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (17.34 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (17.34 mM); Clear solution

* All of the co-solvents are available by MCE.


Synonyms

Butanoic acid, 2-ethyl-, ethyl ester
Butyric acid, 2-ethyl-, ethyl ester
Butyric acid, α-ethyl-, ethyl ester
Ethyl 2-ethylbutyrate
Ethyl α-ethylbutyrate
Ethyl 2-ethylbutanoate
2-Ethylbutyric acid ethyl ester
2-Ethylbutanoic acid ethyl ester
2-Ethyl-n-butyric acid ethyl ester