[CAS NO. 301351-95-1] Arg-AMS
PRODUCTS SPECIFICATIONS [301351-95-1]
DESCRIPTION [301351-95-1]
Overview
| MDL | MFCD31746901 |
|---|---|
| Molecular Weight | 502.51 |
| Molecular Formula | C16H26N10O7S |
| SMILES | NC1=C2N=CN([C@@H]3O[C@H](COS(=O)(NC([C@@H](N)CCCNC(N)=N)=O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 |
Summary
Arg-AMS (compound 24) is a potent nanomolar inhibitor of arginyl tRNA synthetase , which displays tightly bound inhibitory characteristics for the A-domains in non-ribosomal peptide synthetases (NRPS) enzymes [1] .
In Vitro
Arg-AMS inhibits the Orn-activating domain of GrsB with an IC 50 value of 4.6 µM [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
H 2 O : 100 mg/mL ( 199.00 mM ; Need ultrasonic)
DMSO : ≥ 100 mg/mL ( 199.00 mM )
* "≥" means soluble, but saturation unknown.
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 1.9900 mL | 9.9501 mL | 19.9001 mL |
| 5 mM | 0.3980 mL | 1.9900 mL | 3.9800 mL |
| 10 mM | 0.1990 mL | 0.9950 mL | 1.9900 mL |