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[CAS NO. 31271-07-5] Gamma-Mangostin
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-N1957 |
| Brand: | MCE |
| CAS: | 31271-07-5 |
Overview
| MDL | MFCD00951752 |
|---|---|
| Molecular Weight | 396.43 |
| Molecular Formula | C23H24O6 |
| SMILES | O=C1C2=C(OC3=C1C(C/C=C(C)\C)=C(O)C(O)=C3)C=C(O)C(C/C=C(C)\C)=C2O |
Summary
Gamma-Mangostin is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptors antagonist, purified from the fruit hull of the medicinal plant Garcinia mangostana . Gamma-Mangostin is a inhibitor of Transthyretin (TTR) fibrillization , it binds to the thyroxine (T4)-binding sites and stabilized the TTR tetramer [2] . Gamma-Mangostin inhibits [3 H ] spiperone binding to cultured rat aortic myocytes ( IC 50 =3.5 nM) and reduces The perfusion pressure response of rat coronary artery to 5-HT2A ( IC 50 =0.32 µM) [1] .
IC50 & Target
|
5-HT 2A Receptor
|
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 100 mg/mL ( 252.25 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.5225 mL | 12.6126 mL | 25.2251 mL |
| 5 mM | 0.5045 mL | 2.5225 mL | 5.0450 mL |
| 10 mM | 0.2523 mL | 1.2613 mL | 2.5225 mL |
References
Synonyms
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