[CAS NO. 3128-06-1]  Glurate

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PRODUCTS SPECIFICATIONS [3128-06-1]

Catalog
HY-W001957
Brand
MCE
CAS
3128-06-1

DESCRIPTION [3128-06-1]

Overview

MDLMFCD00004412
Molecular Weight130.14
Molecular FormulaC6H10O3
SMILESCC(=O)CCCC(=O)O

For research use only. We do not sell to patients.

Summary

Glurate (4-Acetylbutyric acid; 5-Oxohexanoic acid) can be used to construct antiviral agents (acyclic nucleoside esters) (extracted from patent WO1997030052A1) [1] .


Clinical Trial

NCT Number Sponsor Condition Start Date Phase
NCT05469854 Cinclus Pharma AG
Pharmacokinetics|Cardiodynamic ECG|Safety, and Tolerability|GERD
July 13, 2022 Phase 1

Appearance

Liquid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 768.40 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.6840 mL 38.4202 mL 76.8403 mL
5 mM 1.5368 mL 7.6840 mL 15.3681 mL
10 mM 0.7684 mL 3.8420 mL 7.6840 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (19.21 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (19.21 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (19.21 mM); Clear solution

* All of the co-solvents are available by MCE.


Synonyms

Hexanoic acid, 5-oxo-
Caproic acid, δ-oxo-
5-Oxohexanoic acid
5-Ketohexanoic acid
δ-Ketocaproic acid
γ-Acetylbutyric acid
δ-Oxocaproic acid
4-Acetylbutyric acid
5-Ketocaproic acid
5-Oxocaproic acid
δ-Ketohexanoic acid
NSC 5281