[CAS NO. 32462-30-9]  Oxfenicine

Ships within Stock Price Qty Total
$0.00
$0.00
Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis
request a quote
If there is no stock, or you need other sizes or custom synthesis, please:

PRODUCTS SPECIFICATIONS [32462-30-9]

Catelog
HY-W018026
Brand
MCE
CAS
32462-30-9

DESCRIPTION [32462-30-9]

Overview

MDLMFCD00065932
Molecular Weight167.16
Molecular FormulaC8H9NO3
SMILESO=C(O)[C@@H](N)C1=CC=C(O)C=C1

For research use only. We do not sell to patients.

Summary

Oxfenicine (L-p-Hydroxyphenylglycine) is an orally active carnitine palmitoyltransferase-1 inhibitor. Oxfenicine inhibits the oxidation of fatty acid in heart. Oxfenicine protects heart from necrotic tissue damage during ischaemia [1] [2] .


IC50 & Target

carnitine palmitoyltransferase-1 [1]


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

H 2 O : 4.55 mg/mL ( 27.22 mM ; Need ultrasonic)

DMSO : 1 mg/mL ( 5.98 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.9823 mL 29.9115 mL 59.8229 mL
5 mM 1.1965 mL 5.9823 mL 11.9646 mL
10 mM 0.5982 mL 2.9911 mL 5.9823 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: PBS

    Solubility: 2 mg/mL (11.96 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

* All of the co-solvents are available by MCE.


Synonyms

Benzeneacetic acid, α-amino-4-hydroxy-, (αS)-
Benzeneacetic acid, α-amino-4-hydroxy-, (S)-
Glycine, 2-(p-hydroxyphenyl)-, L-
S)-α-Amino-4-hydroxybenzeneacetic acid
L-(+)-2-(4-Hydroxyphenyl)glycine
L-(p-Hydroxyphenyl)glycine
L-(+)-(p-Hydroxyphenyl)glycine
L-α-Amino-p-hydroxyphenylacetic acid
p-Hydroxy-L-phenylglycine
Oxfenicine
UK 25842
L-(4-Hydroxyphenyl)glycine
L-2-(p-Hydroxyphenyl)glycine
(S)-(4-Hydroxyphenyl)glycine
L-(+)-4-Hydroxyphenylglycine
(S)-2-(4-Hydroxyphenyl)glycine
(S)-2-Amino-2-(4-hydroxyphenyl)acetic acid
(2S)-2-Amino-2-(4-hydroxyphenyl)acetic acid