[CAS NO. 331731-18-1] Adalimumab

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Catalog:	HY-P9908
Brand:	MCE
CAS:	331731-18-1

Overview

MDL	-
Molecular Weight	145425.42
Molecular Formula	-
SMILES	[Adalimumab]

For research use only. We do not sell to patients.

2 Publications Citing Use of MCE

[1]Anal Chim Acta. 2021, 338306.
[2]Xenotransplantation. 2019 Nov;26(6):e12536.

Summary

Adalimumab is a human monoclonal IgG1 antibody targeting tumour necrosis factor α ( TNF-α ).

IC50 & Target

TNF-α ^[1]

In Vitro

Treatment of HUVECs with Adalimumab for up to 12 hours shows no adverse effect on their cell viability, even with a 10-fold higher concentration of Adalimumab than used in this study ^[2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

The elimination half-life (t _1/2 ) of Adalimumab is long (~20 days) ^[1] . The enriched fluorescent-labelled adalimumab is observed mainly in major Oil red O-positive lesions documenting good tissue penetration of the drug into the atherosclerotic plaque, without background fluorescence of the vessel wall after vehicle control injection into hypercholesterolemic Ldlr ^-/- mice ^[2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase
NCT03955861	Belfast Health and Social Care Trust\|British Medical Association\|Psoriasis and Psoriatic Arthritis Alliance\|Queen´s University, Belfast	Psoriatic Arthritis\|Psoriasis\|Enthesitis	February 14, 2019
NCT00595413	EMD Serono\|Merck KGaA, Darmstadt, Germany	Rheumatoid Arthritis	September 2007	Phase 2
NCT00235859	Abbott\|Eisai Limited	Rheumatoid Arthritis	July 2003	Phase 3
NCT04808739	Fundació Institut de Recerca de l´Hospital de la Santa Creu i Sant Pau	Psoriasis	June 1, 2020
NCT00055497	Abbott	Crohn´s Disease	August 2002	Phase 3
NCT03273192	Cinnagen	Bioequivalence\|Phase 1	October 22, 2016	Phase 1
NCT03254810	Synermore Biologics Co., Ltd.	Arthritis, Rheumatoid	September 26, 2017	Phase 1
NCT03885713	Fundación de Investigación Biomédica - Hospital Universitario de La Princesa	Inflammatory Bowel Diseases\|Crohn Disease\|Ulcerative Colitis	September 10, 2019	Phase 4
NCT00497614	University Hospital, Tours	Rheumatoid Arthritis	May 2006	Not Applicable
NCT00827996	Florida Academic Dermatology Centers\|Abbott	Hidradenitis Suppurativa	February 2007	Phase 2
NCT04725422	Seattle Children´s Hospital\|Boston Children´s Hospital, Boston, MA, USA\|Hospital for Special Surgery, New York City, NY, USA\|Joseph M Sanzari Children´s Hospital, Hackensack University Medical Center, Hackensack, NJ, USA\|Riley Children´s Hospital, Indianapolis, IN, USA\|University of North Carolina, Chapel Hill, NC, USA\|Royal Children´s Hospital, Melbourne, Australia\|Hacettepe University, Ankara, Turkey\|Bambino Gesù Children´s Hospital, Rome, Italy\|University of British Columbia, Vancouver, BC, Canada\|Meyer Children´s Hospital, Florence, Italy\|Mansoura University	Chronic Nonbacterial Osteomyelitis\|Chronic Recurrent Multifocal Osteomyelitis	August 1, 2018
NCT02471118	Canadian Research & Education in Arthritis\|AbbVie	Osteoarthritis, Knee	March 2015	Phase 2
NCT00972218	University of Alberta\|Abbott	Spondyloarthritis\|Crohn´s Disease	July 2009	Phase 4
NCT01243671	AbbVie (prior sponsor, Abbott)\|Eisai Co., Ltd.\|AbbVie	Intestinal Behçet´s Disease	October 2010	Phase 3
NCT03221621	Erasmus Medical Center\|Prothya Biosolutions	Hidradenitis Suppurativa	July 31, 2018	Phase 4
NCT01174186	Regionshospitalet Silkeborg\|Abbott\|Medtronic - MITG\|Central Denmark Region	Spondyloarthritis\|Enterocolitis	October 2010	Phase 4
NCT00647491	Abbott\|Eisai Limited	Rheumatoid Arthritis	February 2004	Phase 2\|Phase 3
NCT01119859	Hoffmann-La Roche	Rheumatoid Arthritis	May 2010	Phase 4
NCT00385736	Abbott	Ulcerative Colitis	November 2006	Phase 3
NCT05414201	AbbVie	Non-infectious Intermediate Posterior- or Pan-uveitis	July 7, 2022	Phase 4
NCT00525902	Oregon Health and Science University\|University of Illinois at Chicago\|The Cleveland Clinic	Uveitis	January 2008	Phase 2
NCT02745080	Novartis Pharmaceuticals\|Novartis	Psoriatic Arthritis	April 3, 2017	Phase 3
NCT00274352	Pariser, Robert J., M.D.\|Abbott\|Virginia Clinical Research, Inc.	Sarcoidosis	September 2006	Phase 2
NCT01197144	Karolinska Institutet\|Abbott\|Swedish Foundation for Strategic Research\|The Swedish Research Council	Arthritis, Rheumatoid\|Pain\|Fatigue	October 2010	Not Applicable
NCT00477893	Glostrup University Hospital, Copenhagen\|Abbott	Spondyloarthritis	February 2006	Phase 4
NCT00514982	National Institute of Allergy and Infectious Diseases (NIAID)\|National Institutes of Health Clinical Center (CC)	Hermanski-Pudlak Syndrome\|Colitis\|Cytokines\|Lymphocytes\|Drug Evaluation	August 7, 2007	Phase 2
NCT00736983	Foundation for Liver Research	Crohn´s Disease With Perianal Fistulas	September 2008	Phase 3
NCT01295814	ICStudy, LLC\|Abbott	Interstitial Cystitis	March 2011	Phase 3
NCT04514796	Samsung Bioepis Co., Ltd.	Healthy	August 13, 2020	Phase 1
NCT02489760	Chung Shan Medical University	Ankylosing Spondylitis	July 2008	Phase 4
NCT01986127	Sara Varea\|Hospital Clinic of Barcelona\|Fundacion Clinic per a la Recerca Biomédica	Crohn´s Disease	February 14, 2014	Phase 3
NCT00603993	Abbott\|Abbott Japan Co.,Ltd\|Eisai Co., Ltd.	Rheumatoid Arthritis	March 2006	Phase 3
NCT00730717	Wright State University\|Stanford University\|Wake Forest University Health Sciences	Pyoderma Gangrenosum	May 2009	Phase 2
NCT03789292	Celltrion	Rheumatoid Arthritis	November 26, 2018	Phase 3
NCT00233558	Abbott	Rheumatoid Arthritis	June 2005	Phase 4
NCT01264770	AstraZeneca	Rheumatoid Arthritis	January 2011	Phase 2
NCT05299242	University of Oxford\|National Institute for Health Research, United Kingdom\|180 Life Sciences	Frozen Shoulder	May 27, 2022	Phase 2\|Phase 3
NCT01231321	Abbott	Rheumatoid Arthritis	December 2007	Phase 3
NCT04655807	Janssen Research & Development, LLC	Crohn Disease	March 3, 2021	Phase 2
NCT01877668	Pfizer	Psoriatic Arthritis	January 20, 2014	Phase 3
NCT02332356	Tokyo Medical and Dental University	Crohn Disease	September 2014	Phase 3
NCT00870467	Abbott\|Eisai Co., Ltd.	Rheumatoid Arthritis	March 2009	Phase 3
NCT02480153	Pfizer	Rheumatoid Arthritis	June 25, 2015	Phase 3
NCT03110094	Rennes University Hospital	Rheumatoid Arthritis	March 13, 2017	Not Applicable
NCT05105347	Peking Union Medical College Hospital	Uveitis	November 10, 2021	Phase 4
NCT00735787	Abbott	Psoriasis	August 2008	Phase 4
NCT00235872	Abbott\|Abbott Japan Co.,Ltd\|Eisai Co., Ltd.	Rheumatoid Arthritis	August 2004	Phase 3
NCT02850965	Boehringer Ingelheim	Psoriasis	August 17, 2016	Phase 3
NCT01808118	AbbVie	Axial Spondyloarthritis	April 16, 2013	Phase 3
NCT01500278	UCB Pharma SA\|Parexel\|UCB Pharma	Rheumatoid Arthritis	December 2011	Phase 4
NCT00296894	University Hospital, Ghent	Erosive Osteo-Arthritis	May 2006	Phase 2
NCT01562951	Grupo Espanol de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa\|Abbott\|TFS Trial Form Support	Crohn´s Disease\|Mucosal Inflammation	October 2012	Phase 3
NCT02150473	Heinrich-Heine University, Duesseldorf\|Abbott	Rheumatoid Arthritis	October 2014	Phase 3
NCT04132388	Wake Forest University Health Sciences	Hidradenitis Suppurativa	August 20, 2020	Phase 4
NCT00814866	Université de Sherbrooke\|Abbott	Rheumatoid Arthritis	September 2008	Not Applicable
NCT04870203	University Hospital, Bordeaux\|Eli Lilly and Company\|Biogen\|Ministry for Health and Solidarity, France	Rheumatoid Arthritis	July 15, 2021	Phase 3
NCT03849404	Alvotech Swiss AG	Plaque Psoriasis	February 20, 2019	Phase 3
NCT00291915	Goupe d´Etudes et de Recherche Clinique En Rhumatologie	Rheumatoid Arthritis\|Arthritis	May 2004	Phase 4
NCT03607903	Centre for Human Drug Research, Netherlands\|Leiden University Medical Center\|Leiden Academic Center for Drug Research, the Netherlands	Pain\|Injection Site	July 11, 2018	Phase 1\|Phase 2
NCT04255134	St George´s, University of London	Rheumatoid Arthritis	September 7, 2020	Phase 4
NCT02833350	Genentech, Inc.	Rheumatoid Arthritis	September 9, 2016	Phase 2
NCT01970475	Amgen	Arthritis, Rheumatoid	October 2013	Phase 3
NCT00298272	Biogen\|Hoffmann-La Roche\|Genentech, Inc.	Rheumatoid Arthritis	May 2006	Phase 2
NCT00646178	Abbott	Arthritis\|Psoriatic	June 2003	Phase 3
NCT01629628	Tel-Aviv Sourasky Medical Center\|Abbott	Crohn Disease	July 2012	Phase 3
NCT01021735	University of Glasgow\|Arthritis Research UK\|NHS Lothian\|NHS Grampian\|NHS Tayside\|NHS Borders\|NHS Fife	Rheumatoid Arthritis	April 2010	Phase 4
NCT02557100	Bristol-Myers Squibb	Rheumatoid Arthritis	November 19, 2015	Phase 4
NCT02878083	Nantes University Hospital\|Takeda\|Mauna Kea Technologies\|Institut National de la Santé Et de la Recherche Médicale, France	ULCERATIVE COLITIS	January 11, 2017	Not Applicable
NCT00237887	Abbott	Psoriasis	December 2004	Phase 3
NCT02450513	Universitaire Ziekenhuizen KU Leuven	Crohn´s Disease	March 2012
NCT03505008	Keio University\|Eisai Co., Ltd.	Rheumatoid Arthritis	April 18, 2018	Phase 4
NCT01970488	Amgen	Psoriasis	October 18, 2013	Phase 3
NCT02437253	Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center	Mucopolysaccharidosis Type I\|Mucopolysaccharidosis Type II\|Mucopolysaccharidosis Type VI	May 2015	Phase 1\|Phase 2
NCT05535738	John Harris\|University of Massachusetts, Worcester	Skin Inflammation\|Allergic Contact Dermatitis	September 15, 2022	Phase 2\|Phase 3
NCT01893996	Jonathan Graf\|American College of Rheumatology Research and Education Foundation\|AbbVie\|University of California, San Francisco	Rheumatoid Arthritis\|Cardiovascular Disease	July 2013	Phase 4
NCT04988308	Janssen Research & Development, LLC	Hidradenitis Suppurativa	October 12, 2021	Phase 2
NCT01895764	University Hospital, Tours	Ankylosing Spondylitis	March 2013	Phase 4
NCT02714322	Mylan Inc.\|Mylan GmbH\|Viatris Inc.	Psoriasis\|Arthritis, Psoriatic	June 2015	Phase 3
NCT02207231	Janssen Research & Development, LLC	Psoriasis	November 26, 2014	Phase 3
NCT00311246	University of Chicago\|Abbott	Sarcoidosis	April 2006	Phase 2
NCT02634541	University of Helsinki\|AbbVie	Ankylosing Spondyloarthritis	January 2016	Phase 4
NCT03579823	Alvotech Swiss AG	Healthy Volunteers	May 21, 2018	Phase 1
NCT01088165	Medical University of Vienna	Psoriasis\|Cardiovascular Diseases\|Diabetes Mellitus, Type 2	May 2010	Phase 4
NCT00195663	AbbVie (prior sponsor, Abbott)\|AbbVie	Early Rheumatoid Arthritis	December 2000	Phase 3
NCT01465438	Glostrup University Hospital, Copenhagen\|University Hospital, Gentofte, Copenhagen\|Copenhagen University Hospital at Herlev\|Copenhagen University Hospital, Hvidovre	Psoriatic Arthritis	November 2006	Phase 4
NCT00195676	Abbott	Psoriasis	May 2004	Phase 3
NCT02668640	AbbVie	Rheumatoid Arthritis	May 1, 2016
NCT05057273	Landos Biopharma Inc.	Crohn´s Disease	November 2021	Phase 2
NCT02065622	AbbVie	Ulcerative Colitis (UC)	March 27, 2014	Phase 3
NCT01163617	AbbVie (prior sponsor, Abbott)\|AbbVie	Rheumatoid Arthritis	May 2010	Phase 2
NCT02374021	Brigham and Women´s Hospital\|Columbia University	Arthritis, Rheumatoid	July 2016	Phase 4
NCT01012570	Gerhard Rogler\|University of Zurich	Crohn´s Disease	August 2009
NCT01270035	Keio University\|Saitama Medical University	Rheumatoid Arthritis	January 2011	Phase 4
NCT05151848	Chinese SLE Treatment And Research Group	Takayasu Arteritis	January 5, 2022	Phase 4
NCT01064856	AbbVie (prior sponsor, Abbott)\|AbbVie	Peripheral Spondyloarthritis	February 2010	Phase 3
NCT02198651	AbbVie	Rheumatoid Arthritis\|Musculoskeletal and Connective Tissue Diseases	January 5, 2015	Phase 4
NCT04588818	Sun Yat-sen University	Uveitis	February 1, 2020	Phase 2
NCT04224194	Alvotech Swiss AG	RA	November 4, 2019	Phase 3
NCT03311464	AbbVie	Pyoderma Gangrenosum	October 27, 2017	Phase 3
NCT05172817	Institute for Developing Science and Health Initiatives, Bangladesh\|Universal Medical College Hospital, Bangladesh\|Green Life Center for Rheumatic Care & Research, Bangladesh\|Incepta Pharmaceuticals Ltd, Bangladesh	Pharmacokinetics\|Safety\|Efficacy\|Rheumatoid Arthritis	June 2, 2021	Phase 2\|Phase 3
NCT01405326	The Rheumatological Center of Helsinki\|Abbott	Rheumatoid Arthritis	May 2011	Phase 4
NCT00731757	Wright State University\|Stanford University	Sarcoidosis\|Cutaneous Sarcoidosis	May 2009	Phase 2
NCT03983876	Alvotech Swiss AG	Phase 1	July 1, 2019	Phase 1
NCT02141997	AbbVie	Rheumatoid Arthritis	July 2014	Phase 2
NCT02904902	AbbVie	Hidradenitis Suppurativa	September 6, 2016	Phase 3
NCT01502423	AbbVie (prior sponsor, Abbott)\|AbbVie	Rheumatoid Arthritis	January 2012	Phase 2
NCT00233571	Abbott	Rheumatoid Arthritis	June 2000	Phase 3
NCT04230213	Pfizer	Rheumatoid Arthritis	January 13, 2020	Phase 3
NCT02739828	AbbVie	Hidradenitis Suppurativa	April 7, 2016
NCT02187055	Pfizer	Rhematoid Arthritis	August 2014	Phase 4
NCT00645905	Abbott	Psoriasis	June 2003	Phase 2
NCT00234845	Abbott	Rheumatoid Arthritis	March 2003	Phase 3
NCT01138657	AbbVie (prior sponsor, Abbott)\|AbbVie	Uveitis	August 2010	Phase 3
NCT04705844	Ology Bioservices\|Pharm-Olam, LLC\|Chemical, Biological, Radiological, and Nuclear Medical	Mild to Moderate COVID-19	September 2021	Phase 3
NCT01716039	Alimentiv Inc.\|Abbott	Ulcerative Colitis	June 2013	Phase 2
NCT00448383	Abbott	Rheumatoid Arthritis	September 2002	Phase 3
NCT02852694	PIBD-Net\|European Commission	Crohn´s Disease	February 28, 2017	Phase 4
NCT00427921	Abbott	Crohn´s Disease	January 2007	Phase 3
NCT01387815	AbbVie (prior sponsor, Abbott)\|Cato Research\|JSS Medical Research Inc.\|AbbVie	Psoriasis	August 16, 2011
NCT01382160	University Hospital, Tours	Rheumatoid Arthritis	January 2011	Phase 4
NCT02994836	Fundación de Investigación Biomédica - Hospital Universitario de La Princesa	Crohn´s Disease\|Inflammatory Bowel Disease\|Ulcerative Colitis	April 21, 2017	Phase 4
NCT05527444	Qilu Hospital of Shandong University	Ankylosing Spondylitis	March 15, 2022	Phase 4
NCT01078571	Abbott	Rheumatoid Arthritis	May 2006
NCT01185301	AbbVie (prior sponsor, Abbott)\|AbbVie	Early Rheumatoid Arthritis	October 2010	Phase 3
NCT04088409	Eli Lilly and Company	Uveitis	October 16, 2019	Phase 3
NCT03261102	waqqas.afif\|AbbVie\|McGill University Health Centre+Research Institute of the McGill University Health Centre	Crohn Disease\|Drug Monitoring\|Inflammatory Bowel Diseases	January 17, 2017	Not Applicable
NCT00853099	AbbVie (prior sponsor, Abbott)\|Eisai Co., Ltd.\|AbbVie	Ulcerative Colitis	February 2009	Phase 3
NCT00645892	Abbott	Psoriasis	November 2003	Phase 2
NCT00338650	Abbott	Crohn´s Disease	June 2006	Phase 3
NCT00185562	Stanford University	Osteoarthritis	June 2005	Phase 2
NCT02167139	Samsung Bioepis Co., Ltd.	Rheumatoid Arthritis	May 2014	Phase 3
NCT00929864	Bristol-Myers Squibb	Rheumatoid Arthritis	October 2009	Phase 3
NCT04798755	Hospital San Carlos, Madrid	Uveitis	January 12, 2022	Phase 3
NCT03220841	St Vincent´s Hospital Melbourne\|Australasian Gastro Intestinal Research Foundation\|AbbVie	Crohn Disease\|Inflammatory Bowel Diseases\|Stricture; Bowel	October 9, 2017	Phase 4
NCT05502731	Leiden University Medical Center\|Galapagos NV	Rheumatoid Arthritis	October 2022	Phase 4
NCT01114880	Abbott	Ankylosing Spondylitis	January 2010	Phase 3
NCT00048542	Abbott	Arthritis, Juvenile Idiopathic	September 2002	Phase 3
NCT03561649	University Hospital, Grenoble\|SINNOVIAL	Spondylitis, Ankylosing	June 14, 2018	Not Applicable
NCT02814175	AbbVie	Psoriatic Arthritis	August 5, 2016	Phase 4
NCT02489227	Coherus Biosciences, Inc.	Plaque Psoriasis	August 2015	Phase 3
NCT01283971	Hoffmann-La Roche	Rheumatoid Arthritis	May 2011	Phase 4
NCT04551352	Hoffmann-La Roche	Cutaneous Melanoma\|Uveal Melanoma\|Mucosal Melanoma	October 28, 2020	Phase 1
NCT03357939	Shanghai Henlius Biotech	Immune System Disorder	January 12, 2017	Phase 1
NCT02333383	AbbVie	Ankylosing Spondylitis	December 31, 2014
NCT02330380	University Hospitals Cleveland Medical Center\|National Psoriasis Foundation	Psoriasis\|Inflammation	April 2013
NCT02148718	AbbVie\|Laboratorio Echevarne\|Pivotal S.L.	Moderate to Severe Crohn´s Disease	June 2014	Phase 4
NCT02035800	Université de Sherbrooke\|AbbVie	RheumatoId Arthritis	May 2013	Phase 4
NCT05590455	ANRS, Emerging Infectious Diseases	Tuberculous Meningitis\|HIV I Infection	December 15, 2022	Phase 2
NCT00650156	AbbVie	Rheumatoid Arthritis	June 2007	Phase 1
NCT01166282	AbbVie (prior sponsor, Abbott)\|AbbVie	Enthesitis Related Arthritis (ERA)	September 2010	Phase 3
NCT00348283	Abbott	Crohn´s Disease	August 2006	Phase 3
NCT02629159	AbbVie	Rheumatoid Arthritis	December 1, 2015	Phase 3
NCT01373151	CSL Behring	Rheumatoid Arthritis	June 2011	Phase 2
NCT03104400	AbbVie	Psoriatic Arthritis	April 27, 2017	Phase 3
NCT03100253	Mario Negri Institute for Pharmacological Research	Rheumatoid Arthritis	March 1, 2018	Phase 4
NCT02539849	Hospital Universitari Vall d´Hebron Research Institute\|AbbVie	Crohn Disease	December 2014	Not Applicable
NCT04882683	Shandong Qilu Stem Cells Engineering Co., Ltd.	Ulcerative Colitis	June 1, 2021	Not Applicable
NCT02092467	Pfizer	Arthritis, Rheumatoid	March 14, 2014	Phase 4
NCT02451748	University of Illinois at Chicago\|UCB Pharma	Rheumatoid Arthritis	August 2015	Phase 4
NCT00855608	Rafic Hariri University Hospital\|American University of Beirut Medical Center	Uveitis\|Diabetic Retinopathy\|Choroidal Neovascularization	March 2009	Phase 1
NCT00216177	Hvidovre University Hospital\|University Hospital, Gentofte, Copenhagen	Rheumatoid Arthritis	September 2005	Phase 4
NCT03917303	Maastricht University Medical Center\|Maastricht University\|ZonMw: The Netherlands Organisation for Health Research and Development	Crohn Disease\|Inflammatory Bowel Diseases	December 23, 2019	Phase 4
NCT03153319	Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center	Mucopolysaccharidosis I\|Mucopolysaccharidosis II\|Mucopolysaccharidosis VI	June 5, 2017	Phase 1\|Phase 2
NCT05153200	Ottawa Hospital Research Institute\|The Ottawa Hospital\|University of Ottawa	Rheumatoid Arthritis	January 2022	Phase 4
NCT01971970	Erasmus Medical Center\|Merck Sharp & Dohme LLC	Inflammatory Bowel Diseases	October 2013
NCT00195702	Abbott	Rheumatoid Arthritis	February 2000	Phase 3
NCT00686374	AbbVie (prior sponsor, Abbott)\|AbbVie	Crohn´s Disease	May 1, 2008	Phase 3
NCT00305539	Assistance Publique - Hôpitaux de Paris\|Abbott	Giant Cell Arteritis	May 2006	Phase 3
NCT02196701	AbbVie	Psoriasis	August 5, 2014	Phase 3
NCT00724672	Merck Sharp & Dohme LLC	Rheumatoid Arthritis	September 2008
NCT00645814	Abbott	Psoriasis	March 2003	Phase 2
NCT01872546	Poitiers University Hospital	Chronic Plaque Psoriasis		Phase 2
NCT00427362	Abbott	Psoriatic Arthritis	May 2006	Phase 3
NCT00808509	AbbVie (prior sponsor, Abbott)\|Pharma Consulting Group AB\|AbbVie	Arthritis, Rheumatoid	January 2009	Phase 4
NCT02497469	Takeda	Colitis, Ulcerative	June 29, 2015	Phase 3
NCT02696785	Eli Lilly and Company	Spondyloarthritis	May 2, 2016	Phase 3
NCT00566722	Abbott	Psoriasis	January 2008	Phase 3
NCT01483599	Janssen Inc.	Psoriasis	November 10, 2011	Phase 2
NCT02586831	Camillo Ricordi and Jay Skyler\|Diabetes Research Institute Foundation\|University of Miami	Diabetes Mellitus, Type 1\|Hypoglycemia\|Autoimmune Diseases\|Diabetes Mellitus	December 1, 2023	Phase 1\|Phase 2
NCT00963313	Dr. FRANCISCO J. BLANCO-GARCIA\|Instituto de Investigacion Biomedica de A Coruna	Psoriatic Arthritis	March 2010
NCT00480272	IRCCS Policlinico S. Matteo	Rheumatoid Arthritis	May 2007	Phase 4
NCT00650026	Abbott	Rheumatoid Arthritis
NCT04154852	University of Leeds\|Abbott	Oligoarthritis	June 2011	Phase 2
NCT00667355	Abbott\|Eisai Co., Ltd.	Ankylosing Spondylitis	February 2008	Phase 3
NCT05626348	Qilu Hospital of Shandong University	Arthritis, Rheumatoid	December 22, 2021	Phase 4
NCT01029847	Rigshospitalet, Denmark	Spondyloarthritis	December 2009	Phase 4
NCT01225393	Genentech, Inc.	Rheumatoid Arthritis	November 2010	Phase 2
NCT01870284	Eli Lilly and Company	Spondylitis, Ankylosing	July 2014	Phase 3
NCT00445939	Abbott\|Abbott Japan Co.,Ltd\|Eisai Co., Ltd.	Crohn´s Disease	February 2007	Phase 2\|Phase 3
NCT00690911	Wake Forest University\|Wake Forest University Health Sciences	Sarcoidosis		Phase 2
NCT02565810	Samsung Bioepis Co., Ltd.	Rheumatoid Arthritis	September 2015	Phase 2
NCT01494857	Clalit Health Services	Ulcerative Colitis	January 2012	Phase 3
NCT03849313	Alvotech Swiss AG	Healthy Volunteers	March 20, 2019	Phase 1
NCT03927352	Sinocelltech Ltd.	Psoriasis	September 5, 2019	Phase 3
NCT04115748	Gilead Sciences\|Galapagos NV	Psoriatic Arthritis	December 3, 2019	Phase 3
NCT01870986	Pfizer	Healthy	May 2013	Phase 1
NCT02207244	Janssen Research & Development, LLC	Psoriasis	November 3, 2014	Phase 3
NCT01070303	Abbott	Crohn´s Disease	August 2002	Phase 3
NCT01592292	Hoffmann-La Roche	Rheumatoid Arthritis	November 2011
NCT00939003	AbbVie (prior sponsor, Abbott)\|AbbVie	Axial Spondyloarthritis	July 2009	Phase 3
NCT00195715	Abbott	Crohn´s Disease	September 2004	Phase 3
NCT03412747	UCB Biopharma SRL\|UCB Pharma	Chronic Plaque Psoriasis\|Moderate to Severe Plaque Psoriasis	January 26, 2018	Phase 3
NCT00927069	Innovaderm Research Inc.\|Abbott	Plaque Psoriasis	March 2007	Phase 3
NCT01958827	AbbVie	Crohn´s Disease	September 2013	Phase 3
NCT03172377	Radboud University Medical Center\|Erasmus Medical Center	Crohn Disease in Remission\|Crohn Disease	May 3, 2017	Phase 4
NCT00550446	Pfizer	Arthritis, Rheumatoid	September 2007	Phase 2
NCT01185288	AbbVie (prior sponsor, Abbott)\|AbbVie	Rheumatoid Arthritis	September 2010	Phase 4
NCT02206867	LG Life Sciences	Healthy Subjects	August 2014	Phase 1
NCT01670240	Odense University Hospital\|University of Southern Denmark\|Hvidovre University Hospital\|Aarhus University Hospital\|AbbVie	Ulcerative Colitis\|Pouchitis	August 2012	Phase 3
NCT02912247	Innovent Biologics (Suzhou) Co. Ltd.	Healthy	October 27, 2016	Phase 1
NCT02171429	Hoffmann-La Roche	Ulcerative Colitis	November 14, 2014	Phase 3
NCT01136252	Hospital Universitari Vall d´Hebron Research Institute	Age-Related Macular Degeneration\|Choroidal Neovascularization	May 2010	Phase 2
NCT00647920	Abbott	Rheumatoid Arthritis	July 2003	Phase 3
NCT03180957	University of Oxford\|Department of Health, United Kingdom\|Wellcome Trust\|180 Therapeutics LP	Dupuytren´s Disease	March 2, 2016	Phase 2
NCT01029613	Glostrup University Hospital, Copenhagen	Rheumatoid Arthritis	December 2009
NCT05090124	NHS Greater Glasgow and Clyde\|University of Glasgow	Rheumatoid Arthritis	January 1, 2022	Not Applicable
NCT03059849	McMaster University	Crohn Disease\|Ulcerative Colitis	February 1, 2018	Phase 4
NCT01468207	AbbVie (prior sponsor, Abbott)\|AbbVie	Hidradenitis Suppurativa (HS)	November 2011	Phase 3
NCT03464136	Janssen Scientific Affairs, LLC	Crohn Disease	March 29, 2018	Phase 3
NCT04131322	Fundación Pública Andaluza para la gestión de la Investigación en Sevilla	Crohn Disease\|Ulcerative Colitis	October 10, 2019	Phase 4
NCT01609205	Hamed Rezaei\|Abbott\|Karolinska Institutet	Rheumatoid Arthritis	October 2012	Phase 4
NCT03414502	University of Nebraska	Rheumatoid Arthritis	August 2007	Phase 3
NCT03014947	Fresenius Kabi SwissBioSim GmbH	Healthy Subjects	May 2014	Phase 1
NCT04643483	UCB Biopharma SRL\|UCB Pharma	Crohn´s Disease	June 2021	Phase 3
NCT00796705	National Institute of Allergy and Infectious Diseases (NIAID)	Rheumatoid Arthritis	November 2008	Phase 4
NCT00409682	Abbott	Crohn´s Disease	April 2007	Phase 3
NCT04251741	Reade Rheumatology Research Institute\|ZonMw: The Netherlands Organisation for Health Research and Development\|Sint Maartenskliniek	Rheumatoid Arthritis	July 31, 2020	Phase 4
NCT02163759	Hoffmann-La Roche	Ulcerative Colitis	November 4, 2014	Phase 3
NCT00409617	Abbott	Crohn´s Disease	December 2006	Phase 3
NCT01265823	AbbVie (prior sponsor, Abbott)\|AbbVie	Psoriasis	October 2010	Phase 4
NCT01722214	Innovaderm Research Inc.\|Abbott\|Montreal Heart Institute	Psoriasis\|Vascular Inflammation\|Coronary Atherosclerosis	November 2012	Phase 4
NCT01710358	Eli Lilly and Company	Rheumatoid Arthritis	October 2012	Phase 3
NCT00235105	Charite University, Berlin, Germany\|Abbott	Ankylosing Spondylitis	March 2005	Phase 2\|Phase 3
NCT02871635	Boehringer Ingelheim	Crohn Disease	September 28, 2016	Phase 3
NCT00686439	University of Alberta	Osteoarthritis	June 2008	Phase 1\|Phase 2
NCT00918255	Abbott	Hidradenitis Suppurativa	April 2009	Phase 2
NCT05510063	Samsung Bioepis Co., Ltd.\|Organon and Co	Plaque Psoriasis	August 4, 2022	Phase 4
NCT04009668	University of Michigan	FSGS\|MCD\|Focal Segmental Glomerulosclerosis\|Minimal Change Disease	October 2, 2019	Phase 2
NCT01510548	Kuopio University Hospital	Disc Prolapse\|Pain	March 2007	Phase 3
NCT01148225	AbbVie	Uveitis	November 23, 2010	Phase 3
NCT01635764	AbbVie (prior sponsor, Abbott)\|AbbVie	Hidradenitis Suppurativa	April 2012	Phase 3
NCT03816397	Nisha Acharya\|Children´s Hospital of Philadelphia\|Children´s Hospital Medical Center, Cincinnati\|Children´s Mercy Hospital Kansas City\|National Eye Institute (NEI)\|Great Ormond Street Hospital for Children NHS Foundation Trust\|University Hospitals Bristol and Weston NHS Foundation Trust\|Alder Hey Children´s NHS Foundation Trust\|Seattle Children´s Hospital\|Newcastle-upon-Tyne Hospitals NHS Trust\|University Hospital Southampton NHS Foundation Trust\|Sheffield Children´s NHS Foundation Trust\|Children´s Health\|Sydney Children´s Hospitals Network\|Cambridge University Hospitals NHS Foundation Trust\|Johns Hopkins University\|Norfolk and Norwich University Hospitals NHS Foundation Trust\|Vanderbilt University Medical Center\|University of California, Davis\|University of Texas at Austin\|University of Miami\|Spokane Eye Clinical Research\|University of California, San Francisco	Uveitis\|JIA	March 15, 2020	Phase 4
NCT00573794	AbbVie (prior sponsor, Abbott)\|AbbVie	Ulcerative Colitis	November 28, 2007	Phase 3
NCT05291039	Rehab Werida\|Damanhour University	Irritable Bowel Disease	January 1, 2022	Not Applicable
NCT01235689	AbbVie (prior sponsor, Abbott)\|AbbVie	Crohn´s Disease	February 11, 2011	Phase 3
NCT00235820	Abbott	Psoriasis	July 2005	Phase 3
NCT02808975	AbbVie	Hidradenitis Suppurativa (HS)	July 18, 2016	Phase 4
NCT01736189	AbbVie (prior sponsor, Abbott)\|AbbVie	Rheumatoid Arthritis	October 11, 2012
NCT03172325	Cinnagen	Active Rheumatoid Arthritis	November 18, 2015	Phase 3
NCT02499783	AbbVie	Crohn´s Disease	August 17, 2015	Phase 3
NCT04610476	University of Erlangen-Nürnberg Medical School	Psoriatic Arthritis\|Withdrawal\|Reduction	October 19, 2020	Phase 3
NCT00055523	Abbott	Crohn´s Disease	April 2002	Phase 2
NCT00420927	Abbott	Rheumatoid Arthritis	December 2006	Phase 4
NCT02744755	Sandoz\|Hexal AG	Rheumatoid Arthritis	March 31, 2016	Phase 3
NCT02581345	Momenta Pharmaceuticals, Inc.	Chronic Plaque Psoriasis\|Psoriasis	September 2015	Phase 3
NCT05155592	Dan Liang\|Sun Yat-sen University	Uveitis\|Adalimumab	January 1, 2021	Phase 2
NCT05073315	Amgen	Plaque Psoriasis	October 4, 2021	Phase 3
NCT02019472	Janssen Research & Development, LLC\|GlaxoSmithKline	Arthritis, Rheumatoid	April 4, 2014	Phase 3
NCT05164198	Hanyang University Seoul Hospital\|Linical Korea	Ankylosing Spondylitis\|Axial Spondyloarthritis	January 15, 2022	Phase 4
NCT05372939	Applied Molecular Transport	Ulcerative Colitis	February 5, 2021	Phase 2
NCT01468233	AbbVie (prior sponsor, Abbott)\|AbbVie	Hidradenitis Suppurativa (HS)	November 2011	Phase 3
NCT00195819	Abbott	Ankylosing Spondylitis	December 2003	Phase 3
NCT01704599	Wayne State University\|Abbott	Psoriasis	January 2009	Phase 1\|Phase 2
NCT01000441	University Hospital, Strasbourg, France	Rheumatoid Arthritis	December 23, 2009	Phase 4
NCT05495568	Celltrion	Moderate to Severe Chronic Plaque Psoriasis	November 16, 2022	Phase 3
NCT01657513	University Hospital, Gentofte, Copenhagen\|The Michaelsen Foundation\|Pfizer	Psoriasis	June 2012	Not Applicable
NCT03970824	Celltrion	Healthy	May 31, 2019	Phase 1
NCT00647400	Abbott\|Abbott Japan Co.,Ltd\|Eisai Co., Ltd.	Psoriasis	April 2006	Phase 2\|Phase 3
NCT01338740	University Hospital, Ghent\|Abbott	Crohn´s Disease	April 2011
NCT01644396	AbbVie (prior sponsor, Abbott)\|AbbVie	Moderate to Severe Plaque Psoriasis	May 2012	Phase 4
NCT01295151	Julia Brown\|University of Leeds	Rheumatoid Arthritis	August 2011	Phase 4
NCT02750800	AbbVie	Rheumatoid Arthritis\|Ankylosing Spondylitis\|Psoriatic Arthritis\|Psoriasis\|Crohn´s Disease\|Ulcerative Colitis	April 7, 2016
NCT00077779	Abbott	Crohn´s Disease	July 2003	Phase 3
NCT00133315	Hvidovre University Hospital	Spondylarthropathies\|Ankylosing Spondylitis\|Psoriatic Arthritis	September 2004	Phase 4
NCT00783510	AbbVie	Juvenile Idiopathic Arthritis\|JIA	July 11, 2008
NCT02016482	AbbVie	Nail Psoriasis\|Plaque Psoriasis	January 2014	Phase 3
NCT02256462	Schneider Children´s Medical Center, Israel	Crohn´s Disease	May 1, 2015	Phase 4
NCT03651518	Assistance Publique - Hôpitaux de Paris	Inflammatory Disease\|Autoimmune Diseases	October 20, 2020	Phase 2
NCT01752855	AbbVie (prior sponsor, Abbott)\|AbbVie	Rheumatoid Arthritis	December 2012	Phase 2
NCT00646386	Abbott	Arthritis\|Psoriatic	March 2003	Phase 2
NCT04131504	Children´s Hospital Medical Center, Cincinnati\|The Leona M. and Harry B. Helmsley Charitable Trust	Crohn´s Disease\|IBD	October 16, 2019
NCT04194827	Reade Rheumatology Research Institute\|ZonMw: The Netherlands Organisation for Health Research and Development\|Sint Maartenskliniek	Rheumatoid Arthritis	March 1, 2020	Phase 4
NCT03306446	Groupe d´Etude Therapeutique des Affections Inflammatoires Digestives	CD	March 17, 2015	Phase 4
NCT00696059	Hvidovre University Hospital\|Abbott	Rheumatoid Arthritis\|Arthritis\|Joint Diseases	August 2004	Phase 4
NCT03217734	Jeffrey J Crowley MD\|AbbVie\|Bakersfield Dermatology & Skin Cancer Medical Group	Psoriasis	April 10, 2017	Phase 2\|Phase 3
NCT05313620	Fundación de Investigación Biomédica - Hospital Universitario de La Princesa	Ulcerative Colitis\|Thromboembolism	April 1, 2022	Phase 4
NCT03895203	UCB Biopharma SRL\|UCB Pharma	Psoriatic Arthritis	April 3, 2019	Phase 3
NCT01162421	AbbVie (prior sponsor, Abbott)\|Mount Sinai Hospital, Canada\|AbbVie	Rheumatoid Arthritis	September 2010	Phase 4
NCT02332590	Sanofi\|Regeneron Pharmaceuticals	Rheumatoid Arthritis	January 28, 2015	Phase 3
NCT03739853	University of Oxford	Psoriatic Arthritis	May 14, 2019	Phase 4
NCT02185014	AbbVie	Crohn´s Disease	August 12, 2014	Phase 3
NCT04003922	Assistance Publique Hopitaux De Marseille	Rasmussen Encephalitis	October 20, 2020
NCT01866592	University of Pennsylvania\|AbbVie	Psoriasis\|Cardiovascular Disease	April 2013	Phase 4
NCT00649922	Abbott	Rheumatoid Arthritis	October 2003	Phase 4
NCT01553058	University of Pennsylvania	Psoriasis\|Cardiovascular Disease	July 2012	Phase 4
NCT03828019	JHSPH Center for Clinical Trials	Uveitis	September 17, 2019	Phase 3
NCT01793519	Georgetown University\|National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)\|University of Maryland, College Park\|Washington D.C. Veterans Affairs Medical Center\|Medstar Health Research Institute\|Patient-Centered Outcomes Research Institute\|Arthritis and Pain Associates of PG County\|Arthritis & Rheumatism Associates, P.C.\|Rheumatology Associates of Baltimore, L.L.C.\|The Arthritis Clinic of Northern Virginia, P.C.\|Arthritis and Rheumatic Disease Associates, P.C.	Rheumatoid Arthritis	January 2013	Phase 4
NCT01181570	Innovaderm Research Inc.\|Abbott	Psoriasis\|Sleep Apnea, Obstructive	September 2010	Phase 4
NCT00085644	Abbott	Ankylosing Spondylitis	January 2004	Phase 3
NCT05322473	MoonLake Immunotherapeutics AG	Hidradenitis Suppurativa	April 25, 2022	Phase 2
NCT01646073	AbbVie (prior sponsor, Abbott)\|AbbVie	Plaque Psoriasis	August 2012	Phase 3
NCT02132234	Jagiellonian University\|Departmet of Rheumatology, J Dietl Hospital, Krakow, Poland	Rheumatoid Arthritis\|Psoriatic Arthritis\|Ankylosing Spondylitis\|Hypertension	June 2013	Phase 4
NCT02065570	AbbVie	Crohn´s Disease	May 1, 2014	Phase 3
NCT02533375	AbbVie	Generalized Pustular Psoriasis (GPP)\|Adalimumab\|Japanese	September 28, 2015	Phase 3
NCT02963402	Fundació Institut de Recerca de l´Hospital de la Santa Creu i Sant Pau	Arthritis,Rheumatoid	November 9, 2016
NCT00932113	Tufts Medical Center	Psoriasis	June 2009	Phase 4
NCT01674413	Peter Higgins\|AbbVie\|University of Michigan	Crohn´s Disease	October 2013	Phase 3
NCT00512863	Abbott	Asthma	August 2007	Phase 2
NCT03662919	Biogen	Arthritis, Rheumatoid\|Spondylitis, Ankylosing\|Arthritis, Psoriatic\|Crohn´s Disease\|Colitis, Ulcerative	July 2, 2018
NCT00837434	National Institute of Allergy and Infectious Diseases (NIAID)\|Autoimmunity Centers of Excellence\|Rho Federal Systems Division, Inc.	Rheumatoid Arthritis	March 2009	Phase 4
NCT05590416	Tianjin Medical University	Vogt-Koyanagi-Harada Disease\|Adalimumab	June 1, 2021
NCT00517296	Vanderbilt University Medical Center	Crohn Disease\|Rectal Fistula	January 2008	Phase 4
NCT01564823	Grupo Espanol de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa\|Effice Servicios Para la Investigacion S.L.	Crohn´s Disease	June 2012	Phase 3
NCT02349451	AbbVie	Psoriatic Arthritis	April 28, 2015	Phase 2
NCT00235885	Abbott	Psoriatic Arthritis	July 2005	Phase 3
NCT02706704	American University of Beirut Medical Center	Uveitis\|Non-Infectious Uveitis	February 2016	Phase 2
NCT00597623	Assistance Publique - Hôpitaux de Paris\|Abbott	Hand Osteoarthritis	January 2008	Phase 3
NCT00761514	Abbott	Rheumatoid Arthritis	November 2006	Phase 4
NCT00234897	Abbott	Rheumatoid Arthritis	August 2004	Phase 4
NCT00470509	University Hospital, Geneva	Sciatica	May 2005	Phase 2
NCT04135508	Bio-Thera Solutions	Ankylosing Spondylitis	December 13, 2016	Phase 3
NCT01270087	Skane University Hospital\|Abbott\|The Swedish Research Council\|The Swedish Rheumatism Ass\|Crafoord Foundation	Rheumatoid Arthritis	May 2005	Phase 4
NCT00940862	Innovaderm Research Inc.\|Abbott\|Montreal Heart Institute	Psoriasis\|Vascular Inflammation\|Coronary Atherosclerosis	July 2009	Phase 4
NCT01695239	Eli Lilly and Company	Psoriasis, Arthritic	December 2012	Phase 3
NCT00775437	AbbVie (prior sponsor, Abbott)\|AbbVie	Juvenile Idiopathic Arthritis	March 2009	Phase 3
NCT05427942	Celltrion HealthCare France	Rheumatoid Arthritis\|Ankylosing Spondylarthritis\|Axial Spondyloarthritis Without Radiographic Evidence of Ankylosing Spondylitis\|Psoriatic Arthritis\|Crohn Disease\|Ulcerative Colitis	June 3, 2022
NCT00538902	Abbott	Rheumatoid Arthritis	August 2007	Phase 2\|Phase 3
NCT05015335	Peking Union Medical College Hospital	Uveitis, Anterior\|Adalimumab	August 19, 2021	Phase 4
NCT03737708	Astellas Pharma Korea, Inc.\|Astellas Pharma Inc	Rheumatoid Arthritis (RA)	February 13, 2019	Phase 4
NCT04909801	Bristol-Myers Squibb	Rheumatoid Arthritis	September 15, 2021	Phase 3
NCT04453137	Alvotech Swiss AG	Plaque Psoriasis	June 30, 2020	Phase 3
NCT03248531	UCB Biopharma SRL\|UCB Pharma	Hidradenitis Suppurativa	September 22, 2017	Phase 2
NCT02395055	Biocad	Healthy	June 2015	Phase 1
NCT00234936	Abbott	Rheumatoid Arthritis	December 2003	Phase 3
NCT03151551	Eli Lilly and Company	Psoriatic Arthritis	August 24, 2017	Phase 4
NCT02889796	Gilead Sciences\|Galapagos NV	Rheumatoid Arthritis	August 30, 2016	Phase 3
NCT03619876	Columbia University\|Bristol-Myers Squibb	Rheumatoid Arthritis\|Myocardial Inflammation	July 10, 2019	Phase 4
NCT01078610	Abbott	Psoriatic Arthritis
NCT01124838	AbbVie (prior sponsor, Abbott)\|AbbVie	Uveitis	August 2010	Phase 3
NCT00513370	Abbott	Psoriasis	September 2007	Phase 3
NCT02322008	Regionshospitalet Viborg, Skive	Crohn´s Disease\|Ulcerative Colitis\|Inflammatory Bowel Disease	September 2009
NCT02016105	Sandoz\|Hexal AG	Plaque Type Psoriasis	December 2013	Phase 3
NCT00049751	Abbott	Rheumatoid Arthritis	September 2002	Phase 3
NCT02015793	AbbVie	Crohn´s Disease	December 2013	Phase 2
NCT02694523	AbbVie\|Boehringer Ingelheim	Psoriasis	March 2016	Phase 3
NCT00348153	Heidelberg University\|Abbott	Uveitis	August 2006	Phase 2\|Phase 3
NCT03016260	TcLand Expression S.A.\|European Commission	RheumatoId Arthritis	December 2016
NCT02092961	AstraZeneca	Rheumatoid Arthritis	February 2011	Phase 2
NCT01251614	AbbVie (prior sponsor, Abbott)\|AbbVie	Plaque Psoriasis	December 2010	Phase 3
NCT01144156	Rabin Medical Center\|Abbott	Crohn´s Disease		Not Applicable
NCT01706692	Swiss Dermatology Network for Targeted Therapies	Psoriasis	July 2011
NCT04089514	Biogen	Arthritis, Rheumatoid (RA)\|Axial Spondyloarthritis (axSpA)\|Arthritis, Psoriatic (PsA)\|Crohn´s Disease (CD)\|Colitis, Ulcerative (UC)	June 30, 2019
NCT01764997	Sanofi\|Regeneron Pharmaceuticals	Rheumatoid Arthritis	April 2013	Phase 3
NCT02897115	AbbVie\|IST GmbH, Germany\|Hannover Medical School\|Improvement by Movement GmbH, Germany	Axial Spondyloarthritis	September 12, 2016	Phase 4
NCT00195650	Abbott	Rheumatoid Arthritis	July 2000	Phase 3
NCT01561313	AbbVie (prior sponsor, Abbott)\|AbbVie	Rheumatoid Arthritis	March 2012	Phase 2
NCT00814255	NYU Langone Health\|University of Michigan\|The Cleveland Clinic\|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	Focal Segmental Glomerulosclerosis	December 2008	Phase 2
NCT00445432	Abbott\|Eisai Co., Ltd.	Crohn´s Disease	March 2007	Phase 2\|Phase 3
NCT02840175	Assistance Publique - Hôpitaux de Paris	Juvenile Idiopathic Arthritis	May 18, 2017	Phase 3
NCT02056184	University of Leeds\|AbbVie\|Theorem	Rheumatoid Arthritis\|Targeted Ultrasound	December 2013	Phase 4
NCT02929251	Assistance Publique - Hôpitaux de Paris	Uveitis\|Biotherapy	June 28, 2017	Phase 2
NCT02632175	AbbVie	Ulcerative Colitis	November 26, 2015	Phase 3
NCT02760407	R-Pharm International, LLC\|Quintiles, Inc.\|OCT Clinical Trials\|R-Pharm	Rheumatoid Arthritis	May 24, 2016	Phase 3
NCT00660647	University of Aarhus\|Abbott\|Meda Pharmaceuticals\|Aarhus University Hospital	Arthritis, Rheumatoid	September 2007	Phase 3
NCT00234884	Abbott	Rheumatoid Arthritis	September 2003
NCT00105300	Abbott	Crohn´s Disease	October 2004	Phase 3
NCT01320293	University of North Carolina, Chapel Hill\|AbbVie	Psoriasis	March 2011	Not Applicable
NCT00193648	Northwell Health\|University of North Carolina\|The Cleveland Clinic	Focal Glomerulosclerosis	July 2005	Phase 1
NCT01505491	Boehringer Ingelheim	Healthy	December 1, 2011	Phase 1
NCT04171414	Celltrion\|PPD	Rheumatoid Arthritis	September 9, 2019	Phase 3
NCT02113904	Assistance Publique - Hôpitaux de Paris	Netherton Syndrome	January 27, 2014	Phase 2
NCT02492217	Universidade Nova de Lisboa	Ankylosing Spondylitis	May 2015	Phase 4
NCT01550965	AbbVie (prior sponsor, Abbott)\|AbbVie	Ulcerative Colitis	May 2012	Phase 3
NCT00574249	Abbott	Chronic Plaque Psoriasis	November 2007	Phase 3
NCT01768858	AbbVie\|Raffeiner GmbH	Rheumatoid Arthritis\|Ankylosing Spondylitis\|Psoriatic Arthritis\|Crohn´s Disease\|Ulcerative Colitis\|Plaque Psoriasis	February 5, 2013
NCT02878161	Fen Li\|Central South University	Rheumatoid Arthritis	January 2016	Phase 4
NCT00234234	University Hospital, Rouen	Rheumatoid Arthritis	January 2006	Phase 4
NCT03316781	Shanghai Henlius Biotech	Plaque Psoriasis	October 27, 2017	Phase 3
NCT04183608	Groupe d´Etude Therapeutique des Affections Inflammatoires Digestives\|AbbVie	Ulcerative Colitis	January 14, 2020	Phase 4
NCT04527380	Eli Lilly and Company	Juvenile Psoriatic Arthritis\|Enthesitis Related Arthritis	April 13, 2021	Phase 3
NCT00235833	Abbott\|Abbott Japan Co.,Ltd\|Eisai Co., Ltd.	Rheumatoid Arthritis	June 2003	Phase 2
NCT00650390	Abbott	Rheumatoid Arthritis
NCT02764762	Takeda	Crohn Disease	June 12, 2017	Phase 4
NCT04404517	Hospital Universitario La Paz	Inflammatory Bowel Diseases	October 1, 2019	Phase 3
NCT03823391	AbbVie	Rheumatoid Arthritis (RA)	March 27, 2019	Phase 2
NCT04300686	Shanghai Zhongshan Hospital	Takayasu Arteritis\|Tocilizumab\|Adalimumab\|Treatment	March 1, 2020	Phase 4
NCT04222920	Reade Rheumatology Research Institute\|ZonMw: The Netherlands Organisation for Health Research and Development\|Sint Maartenskliniek	Rheumatoid Arthritis	March 1, 2020	Phase 4
NCT00690573	Abbott\|Eisai Co., Ltd.	Juvenile Rheumatoid Arthritis	May 2008	Phase 3
NCT00646191	Abbott	Psoriasis	March 2003	Phase 2
NCT02393378	Takeda	Rheumatoid Arthritis	April 8, 2015	Phase 2
NCT00647270	Abbott	Rheumatoid Arthritis	December 2007	Phase 3
NCT00421642	Mayo Clinic	Ulcerative Colitis	October 2006	Phase 1
NCT01556672	Innovaderm Research Inc.\|Abbott	Plaque Psoriasis\|Crohn´s Disease	April 2012	Phase 4
NCT02252809	Brugmann University Hospital	Innate Immunity	November 2008	Early Phase 1
NCT01812954	Jochen Schmitt.\|Merck Sharp & Dohme LLC\|Technische Universität Dresden	Psoriasis	March 2013
NCT00408629	Abbott	Ulcerative Colitis	November 2006	Phase 3
NCT02516774	Gustave Roussy, Cancer Campus, Grand Paris	Anaplastic Thyroid Cancers	December 2014	Phase 1
NCT05108259	Prestige Biopharma Limited	Healthy Volunteers	March 30, 2022	Phase 1
NCT02893254	Innovent Biologics (Suzhou) Co. Ltd.	AS	September 22, 2016	Phase 3
NCT02097264	Novo Nordisk A+S	Inflammation\|Rheumatoid Arthritis	September 2014	Phase 2
NCT00649545	Abbott	Rheumatoid Arthritis
NCT00690846	Wake Forest University Health Sciences	Pyoderma Gangrenosum	July 2007	Phase 2
NCT04646187	University Medical Center Groningen\|European Crohn´s and Colitis Organisation\|Bühlmann Laboratories AG	Inflammatory Bowel Diseases\|Crohn Disease\|Colitis, Ulcerative	March 11, 2021	Phase 4
NCT02065557	AbbVie	Ulcerative Colitis	October 13, 2014	Phase 3
NCT00478660	Abbott	Ankylosing Spondylitis	February 2006	Phase 3
NCT01497717	Rambam Health Care Campus\|Abbott	Arthritis; Behcet	July 2013	Phase 3
NCT02927353	Meiji Seika Pharma Co., Ltd.	Healthy Volunteer	August 2016	Phase 1

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References

[1] Ternant D, et al. Pharmacokinetics and concentration-effect relationship of adalimumab in rheumatoid arthritis. Br J Clin Pharmacol. 2015 Feb;79(2):286-97.
[2] Oberoi R, et al. Targeting Tumor Necrosis Factor-α with Adalimumab: Effects on Endothelial Activation and Monocyte Adhesion. PLoS One. 2016 Jul 28;11(7):e0160145.

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