[CAS NO. 33627-28-0] Britannin

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PRODUCTS SPECIFICATIONS [33627-28-0]

Catelog

HY-N3005

Brand

MCE

CAS

33627-28-0

DESCRIPTION [33627-28-0]

Overview

MDL	-
Molecular Weight	366.41
Molecular Formula	C19H26O7
SMILES	C[C@]12[C@@]([C@@H](C[C@@](O3)([H])[C@](C(C3=O)=C)([H])[C@@H]2OC(C)=O)C)([H])[C@@H](OC(C)=O)C[C@@H]1O

For research use only. We do not sell to patients.

Summary

Britannin, isolated from Inula aucheriana , is a sesquiterpene lactone. Britannin induces apoptosis and autophagy by activating AMPK regulated by ROS in liver cancer cells. Britannin has anti-proliferative and anti-inflammatory activities ^[1] ^[2] ^[3] .

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 250 mg/mL ( 682.30 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.7292 mL	13.6459 mL	27.2918 mL
5 mM	0.5458 mL	2.7292 mL	5.4584 mL
10 mM	0.2729 mL	1.3646 mL	2.7292 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.08 mg/mL (5.68 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.08 mg/mL (5.68 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.08 mg/mL (5.68 mM); Clear solution

* All of the co-solvents are available by MCE.