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[CAS NO. 345892-71-9] SB-611812
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-10664 |
| Brand: | MCE |
| CAS: | 345892-71-9 |
Overview
| MDL | - |
|---|---|
| Molecular Weight | 491.74 |
| Molecular Formula | C17H16Cl3F3N2O3S |
| SMILES | O=S(NC1=CC=C(C(OCCN(C)C)=C1)Cl)(C2=C(C=C(C(F)(F)F)C=C2Cl)Cl)=O |
Summary
SB-611812 is a urotensin II receptor (UTR) antagonist with the potential in the treatment of cardiovascular disease [1] [2] .
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 16.67 mg/mL ( 33.90 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.0336 mL | 10.1680 mL | 20.3360 mL |
| 5 mM | 0.4067 mL | 2.0336 mL | 4.0672 mL |
| 10 mM | 0.2034 mL | 1.0168 mL | 2.0336 mL |
References
- [1] Rakowski E, et al. A role for urotensin II in restenosis following balloon angioplasty: use of a selective UT receptor blocker. J Mol Cell Cardiol. 2005 Nov;39(5):785-91.
- [2] Cosenzi A. Non peptidic urotensin II antagonists: perspectives for a new class of drugs. Cardiovasc Hematol Agents Med Chem. 2008 Apr;6(2):80-91.
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