[CAS NO. 36284-77-2] Hederasaponin B

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PRODUCTS SPECIFICATIONS [36284-77-2]

Catalog

HY-N0306

Brand

MCE

CAS

36284-77-2

DESCRIPTION [36284-77-2]

Overview

MDL	-
Molecular Weight	1205.38
Molecular Formula	C59H96O25
SMILES	O[C@@H]1[C@H](O)[C@@H](O[C@@]2([H])[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O2)[C@]([H])(O[C@@H]3C(C)(C)[C@@](CC[C@]4(C)[C@@]5(CC=C6[C@]4(CC[C@]7(C(O[C@@H]8O[C@H](CO[C@H]9[C@H](O)[C@@H](O)[C@H](O[C@@]%10([H])[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O%10)[C@@H](CO)O9)[C@@H](O)[C@H](O)[C@H]8O)=O)[C@@]6([H])CC(C)(C)CC7)C)[H])([H])[C@]5(C)CC3)OC1

For research use only. We do not sell to patients.

Summary

Hederasaponin B, isolated from Hedera helix , has broad-spectrum antiviral activity against various subgenotypes of Enterovirus 71 (EV71).

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 82.96 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.8296 mL	4.1481 mL	8.2961 mL
5 mM	0.1659 mL	0.8296 mL	1.6592 mL
10 mM	0.0830 mL	0.4148 mL	0.8296 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (2.07 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (2.07 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (2.07 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Song J, et al. Antiviral Activity of Hederasaponin B from Hedera helix against Enterovirus 71 Subgenotypes C3 and C4a. Biomol Ther (Seoul). 2014 Jan;22(1):41-6.

Synonyms

Olean-12-en-28-oic acid, 3-[[2-O-(6-deoxy-α-L-mannopyranosyl)-α-L-arabinopyranosyl]oxy]-, O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester, (3β)-

Eleutheroside M

Hederacoside B

Hederasaponin B

Hederacolchiside C

Tauroside G₂

Tauroside St-G₂

Glycoside L-G₂

Saponin Pl₃

Hederagenin B

3-O-α-L-Rhamnopyranosyl-(1→2)-α-L-arabinopyranosyloleanolic acid 28-O-α-L-rhamnopyranosyl-(1→4)-β-D-glucopyranose-(1→6)-β-D-glucopyranoside