[CAS NO. 370073-65-7] STK683963

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PRODUCTS SPECIFICATIONS [370073-65-7]

Catalog

HY-W287569

Brand

MCE

CAS

370073-65-7

DESCRIPTION [370073-65-7]

Overview

MDL	-
Molecular Weight	277.27
Molecular Formula	C12H8FN3O2S
SMILES	O=C1C=C(O)C(SC(NC2=CC=C(F)C=C2)=N3)=C3N1

For research use only. We do not sell to patients.

Summary

STK683963 is a strong activator of cellular ATG4B activity. STK683963 can act as a mediator of redox-regulation of ATG4B in cells. STK683963 can be used for the research of cancer ^[1] .

In Vitro

STK683963 (0-50 μM) strongly up-regulates the luciferase release reporter in a dosedependent manner after 24 h ^[1] .
STK683963 strongly activates luciferase release, which was completely blocked in the presence of NAC ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

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References

[1] Niccolo Pengo, et al. Identification of Kinases and Phosphatases That Regulate ATG4B Activity by siRNA and Small Molecule Screening in Cells. Front Cell Dev Biol. 2018 Nov 1;6:148.