[CAS NO. 382607-78-5] O6BTG-octylglucoside
PRODUCTS SPECIFICATIONS [382607-78-5]
DESCRIPTION [382607-78-5]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 616.53 |
| Molecular Formula | C24H34BrN5O7S |
| SMILES | [H][C@]1([C@]([H])(O[C@@](OCCCCCCCCN2C3=C(N=C2)C(OCC4=CC(Br)=CS4)=NC(N)=N3)([C@](O)([C@]1(O)[H])[H])[H])CO)O |
3 Publications Citing Use of MCE
Summary
O6BTG-octylglucoside is a potent O 6 -methylguanine-DNAmethyl-transferase ( MGMT ) inhibitor, with IC 50 s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells.
IC50 & Target
|
MGMT 32 nM (IC 50 ) |
In Vitro
O6BTG-octylglucoside is a potent and non-toxic MGMT inhibitor, with IC 50 s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 100 mg/mL ( 162.20 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 1.6220 mL | 8.1099 mL | 16.2198 mL |
| 5 mM | 0.3244 mL | 1.6220 mL | 3.2440 mL |
| 10 mM | 0.1622 mL | 0.8110 mL | 1.6220 mL |