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[CAS NO. 388575-52-8] PSN 375963
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-108258 |
| Brand: | MCE |
| CAS: | 388575-52-8 |
Overview
| MDL | MFCD01829706 |
|---|---|
| Molecular Weight | 285.38 |
| Molecular Formula | C17H23N3O |
| SMILES | CCCCC1CCC(C2=NC(C3=CC=NC=C3)=NO2)CC1 |
Summary
In Vitro
The endogenous ligand OEA signals through GPR119 in a manner similar to glucagon-like peptide-1 (GLP-1) and its receptor with respect to insulin secretion, intracellular calcium and cAMP [2] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 50 mg/mL ( 175.20 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 3.5041 mL | 17.5205 mL | 35.0410 mL |
| 5 mM | 0.7008 mL | 3.5041 mL | 7.0082 mL |
| 10 mM | 0.3504 mL | 1.7520 mL | 3.5041 mL |
References
- [1] Overton HA, et al. Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents. Cell Metab. 2006;3(3):167-175.
- [2] Ning Y, et al. Endogenous and synthetic agonists of GPR119 differ in signalling pathways and their effects on insulin secretion in MIN6c4 insulinoma cells. Br J Pharmacol. 2008;155(7):1056-1065.
Synonyms
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