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[CAS NO. 4097-22-7] 2',3'-Dideoxyadenosine
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-W013441 |
| Brand: | MCE |
| CAS: | 4097-22-7 |
Overview
| MDL | MFCD00010534 |
|---|---|
| Molecular Weight | 235.24 |
| Molecular Formula | C10H13N5O2 |
| SMILES | OC[C@@H]1CC[C@H](N2C(N=CN=C3N)=C3N=C2)O1 |
Summary
IC50 & Target
|
HIV-1
|
HIV-2
|
In Vitro
2',3'-Dideoxyadenosine inhibits HIV-1 and simian immunodeficiency virus (SIV) in MT-4 cells with EC 50 s of 5.27 and 5.3 μM, respectively. 2',3'-Dideoxyadenosine inhibits HIV-1 and HIV-2 in human T-lymphocyte CEM cells with EC 50 s of 4 μM and 8 μM, respectively. 2',3'-Dideoxyadenosine inhibits HIV-1 and HIV-2 in Molt 4/C8 cells with EC 50 s of 4 μM and 5.5 μM, respectively. 2',3'-Dideoxyadenosine inhibits HIV-1 and HIV-2 in C8166 cells with EC 50 s of 17 μM and 22 μM, respectively. 2',3'-Dideoxyadenosine inhibits murine sarcoma virus (MSV) in C3H/3T3 cells with an EC 50 of 24 μM [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL ( 425.10 mM ; Need ultrasonic)
H 2 O : 100 mg/mL ( 425.10 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 4.2510 mL | 21.2549 mL | 42.5098 mL |
| 5 mM | 0.8502 mL | 4.2510 mL | 8.5020 mL |
| 10 mM | 0.4251 mL | 2.1255 mL | 4.2510 mL |
-
1.
Add each solvent one by one: PBS
Solubility: 14.29 mg/mL (60.75 mM); Clear solution; Need ultrasonic and warming and heat to 60°C
-
2.
-
3.
Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)
Solubility: ≥ 2.08 mg/mL (8.84 mM); Clear solution
-
4.
Add each solvent one by one: 10% DMSO >> 90% corn oil
Solubility: ≥ 2.08 mg/mL (8.84 mM); Clear solution
Synonyms
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