[CAS NO. 41089-03-6] Demethyl bleomycin A2

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PRODUCTS SPECIFICATIONS [41089-03-6]

Catalog

HY-148649

Brand

MCE

CAS

41089-03-6

DESCRIPTION [41089-03-6]

Overview

MDL	-
Molecular Weight	1400.52
Molecular Formula	C54H81N17O21S3
SMILES	O=C(C1=NC([C@H](CC(N)=O)NC[C@H](N)C(N)=O)=NC(N)=C1C)N[C@H](C(N[C@H](C)[C@@H](O)[C@H](C)C(N[C@@H]([C@H](O)C)C(NCCC2=NC(C3=NC(C(NCCCSC)=O)=CS3)=CS2)=O)=O)=O)[C@H](C4=CN=CN4)O[C@H]5[C@H]([C@H]([C@@H]([C@@H](O5)CO)O)O)O[C@@H]6[C@H]([C@H]([C@@H]([C@H](O6)CO)O)OC(N)=O)O

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Summary

Demethyl bleomycin A2 is a Bleomycin (HY-108345) congener. The DNA cleavage of demethyl bleomycin A2 is insensitive to the presence of 5-Methylcytidine (HY-113135) ^[1] .

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Please store the product under the recommended conditions in the Certificate of Analysis.

References

[1] Hertzberg RP, et al. Degradation of structurally modified DNAs by bleomycin group antibiotics. Biochemistry. 1988 May 3;27(9):3164-74.