[CAS NO. 4254-14-2] (R)-(-)-1,2-Propanediol

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PRODUCTS SPECIFICATIONS [4254-14-2]

Catelog

HY-Z0031

Brand

MCE

CAS

4254-14-2

DESCRIPTION [4254-14-2]

Overview

MDL	MFCD00066248
Molecular Weight	76.09
Molecular Formula	C3H8O2
SMILES	C[C@@H](O)CO

For research use only. We do not sell to patients.

Summary

(R)-(-)-1,2-Propanediol is a (R)-enantiomer of 1,2-Propanediol that produced from glucose in Escherichia coli expressing NADH-linked glycerol dehydrogenase genes ^[1] .

IC50 & Target

Microbial Metabolite

Appearance

Liquid

Source

E. coli

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 1314.23 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	13.1423 mL	65.7117 mL	131.4233 mL
5 mM	2.6285 mL	13.1423 mL	26.2847 mL
10 mM	1.3142 mL	6.5712 mL	13.1423 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (32.86 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (32.86 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (32.86 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] N E Altaras, et al. Metabolic engineering of a 1,2-propanediol pathway in Escherichia coli. Appl Environ Microbiol. 1999 Mar;65(3):1180-5.

Synonyms

1,2-Propanediol, (R)-

1,2-Propanediol, (R)-(-)-

(-)-Propylene glycol

1-Deoxy-sn-glycerol

R-(-)-Propylene glycol

D-(-)-Propanediol

(-)-1,2-Propanediol

(R)-1,2-Propanediol

R-(-)-1,2-Propanediol

(R)-2-Hydroxy-1-propanol

(R)-Propylene glycol

NSC 90793

(2R)-1,2-Propanediol

1,2-Propanediol, (2R)-

1,2-Propanediol, (R)-

(R)-(-)-1,2-Propanediol

(2R)-Propane-1,2-diol