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[CAS NO. 442665-87-4] OGT-IN-2
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-136282 |
| Brand: | MCE |
| CAS: | 442665-87-4 |
Overview
| MDL | - |
|---|---|
| Molecular Weight | 446.99 |
| Molecular Formula | C23H27ClN2O3S |
| SMILES | O=C(C1)N(/C(SC1C(O)=O)=N/C(C=C2)=CC=C2Cl)CCC3(C[C@H](C4)C5)C[C@H]5C[C@H]4C3 |
Summary
OGT-IN-2 (compound 4) is a potent O-GlcNAc transferase (OGT) inhibitor, with IC 50 values of 30 and 53 μM for sOGT and ncOGT, respectively [1] .
IC50 & Target
IC50: 30 ± 2 μM (sOGT), 53 ± 7 μM (ncOGT) [1]
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 125 mg/mL ( 279.65 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.2372 mL | 11.1859 mL | 22.3719 mL |
| 5 mM | 0.4474 mL | 2.2372 mL | 4.4744 mL |
| 10 mM | 0.2237 mL | 1.1186 mL | 2.2372 mL |
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