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[CAS NO. 4608-49-5] Larixyl acetate
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-101795 |
| Brand: | MCE |
| CAS: | 4608-49-5 |
Overview
| MDL | - |
|---|---|
| Molecular Weight | 348.52 |
| Molecular Formula | C22H36O3 |
| SMILES | CC(CCC1)(C)[C@]([C@@]1(C)[C@H]2CC[C@](C)(O)C=C)([H])[C@@H](OC(C)=O)CC2=C |
Summary
IC50 & Target
|
hTRPC6 0.58 μM (IC 50 ) |
hTRPC3 6.83 μM (IC 50 ) |
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 100 mg/mL ( 286.93 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.8693 mL | 14.3464 mL | 28.6928 mL |
| 5 mM | 0.5739 mL | 2.8693 mL | 5.7386 mL |
| 10 mM | 0.2869 mL | 1.4346 mL | 2.8693 mL |
References
- [1] Urban N, et al. Identification and Validation of Larixyl Acetate as a Potent TRPC6 Inhibitor. Mol Pharmacol. 2016 Jan;89(1):197-213.
- [2] Chen X, et al. The TRPC6 inhibitor, larixyl acetate, is effective in protecting against traumatic brain injury-induced systemic endothelial dysfunction. J Neuroinflammation. 2019 Jan 31;16(1):21.
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