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[CAS NO. 498-02-2] Apocynin
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-N0088 |
| Brand: | MCE |
| CAS: | 498-02-2 |
Overview
| MDL | MFCD00008747 |
|---|---|
| Molecular Weight | 166.17 |
| Molecular Formula | C9H10O3 |
| SMILES | CC(C1=CC=C(O)C(OC)=C1)=O |
12 Publications Citing Use of MCE
- [1]Redox Biol. 2018 May;15:418-434.
- [2]Cell Mol Gastroenterol Hepatol. 2022 Oct 21;S2352-345X(22)00222-3.
- [3]Free Radic Biol Med. 2021 Mar 16;S0891-5849(21)00113-1.
- [4]Exp Mol Med. 2021 Sep;53(9):1307-1318.
- [5]Biomed Pharmacother. 2022 Jul;151:113098.
- [6]Biomed Pharmacother. 2020 Jan;121:109615.
- [7]Commun Biol. 2022 Jul 22;5(1):726.
- [8]Sci Rep. 2017 Aug 29;7(1):9873.
- [9]Atherosclerosis. 2021 Apr 14.
- [10]Eur J Pharmacol. 2020 Jun 5;876:173058.
- [11]Biochem Biophys Res Commun. 2021 May 1;559:191-196.
- [12]Research Square Preprint. 2021 Sep.
Summary
Apocynin is a selective NADPH-oxidase inhibitor with an IC 50 of 10 μM.
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date | Phase |
|---|---|---|---|---|
| NCT03680404 | The University of Texas at Arlington |
Cardiovascular Diseases|Cardiovascular Risk Factor|Vasoconstriction
|
October 1, 2018 | Phase 1 |
| NCT03680573 | The University of Texas at Arlington |
Cardiovascular Diseases|Cardiovascular Risk Factor|Vasoconstriction
|
January 8, 2018 | Phase 1 |
| NCT03680638 | The University of Texas at Arlington |
Cardiovascular Diseases|Cardiovascular Risk Factor|Vasodilation
|
September 7, 2016 | Phase 1 |
| NCT00992667 | Medical University of Lodz|Ministry of Science and Higher Education, Poland |
Bronchial Asthma
|
June 2008 | Phase 1 |
| NCT01402297 | Medical University of Lodz|Ministry of Science and Higher Education, Poland |
Chronic Obstructive Pulmonary Disease
|
October 2010 | Phase 1 |
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : ≥ 100 mg/mL ( 601.79 mM )
H 2 O : ≥ mg/mL
* "≥" means soluble, but saturation unknown.
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 6.0179 mL | 30.0897 mL | 60.1793 mL |
| 5 mM | 1.2036 mL | 6.0179 mL | 12.0359 mL |
| 10 mM | 0.6018 mL | 3.0090 mL | 6.0179 mL |
References
Synonyms
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