[CAS NO. 507487-89-0]  CK7

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PRODUCTS SPECIFICATIONS [507487-89-0]

Catalog
HY-103646
Brand
MCE
CAS
507487-89-0

DESCRIPTION [507487-89-0]

Overview

MDL-
Molecular Weight328.35
Molecular FormulaC14H12N6O2S
SMILESO=[N+](C1=CC(NC2=NC=CC(C3=C(C)N=C(N)S3)=N2)=CC=C1)[O-]

For research use only. We do not sell to patients.

Summary

CK7, a Cdk2/9 inhibitor, can be used for the synthesis of Nek1 inhibitor BSc5231 and BSc5367 [1] .


IC50 & Target

CDK2

CDK9


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)


Solvent & Solubility

In Vitro:

DMSO : 12.5 mg/mL ( 38.07 mM ; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0455 mL 15.2277 mL 30.4553 mL
5 mM 0.6091 mL 3.0455 mL 6.0911 mL
10 mM 0.3046 mL 1.5228 mL 3.0455 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.08 mg/mL (6.33 mM); Clear solution

* All of the co-solvents are available by MCE.