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[CAS NO. 508186-14-9] Ac-CoA Synthase Inhibitor1
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-104032 |
| Brand: | MCE |
| CAS: | 508186-14-9 |
Overview
| MDL | MFCD03232237 |
|---|---|
| Molecular Weight | 410.51 |
| Molecular Formula | C20H18N4O2S2 |
| SMILES | O=C(NCCOC)NC1=CC=C2N=C(C3=CC=CS3)C(C4=CC=CS4)=NC2=C1 |
Summary
In Vitro
Ac-CoA Synthase Inhibitor1 inhibits cellular [ 14 C]acetate uptake into both lipids and histones with an IC 50 of 5 µM. Ac-CoA Synthase Inhibitor1 inhibits the ability of HepG2 cells to incorporate [ 14 C]acetate into lipids with IC 50 of 6.8 µM. Ac-CoA Synthase Inhibitor1 inhibits HepG2 utilization of [ 14 C]acetate for histone acetylation with IC 50 of 5.5 µM [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 31.25 mg/mL ( 76.12 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.4360 mL | 12.1800 mL | 24.3599 mL |
| 5 mM | 0.4872 mL | 2.4360 mL | 4.8720 mL |
| 10 mM | 0.2436 mL | 1.2180 mL | 2.4360 mL |
References
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