[CAS NO. 5144-89-8] o-Phenanthroline monohydrate
PRODUCTS SPECIFICATIONS [5144-89-8]
DESCRIPTION [5144-89-8]
Overview
| MDL | MFCD00149973 |
|---|---|
| Molecular Weight | 198.22 |
| Molecular Formula | C12H10N2O |
| SMILES | C12=C(N=CC=C3)C3=CC=C1C=CC=N2.O |
Summary
o-Phenanthroline (1,10-Phenanthroline) monohydrate, a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells. o-Phenanthroline monohydrate forms a red chelate with Fe 2+ that absorbs maximally at 510 nm. o-Phenanthroline (1,10-Phenanthroline) monohydrate is also a MMP inhibitor [1] [2] .
In Vitro
o-Phenanthroline (1,10-Phenanthroline, 1mM) inhibits autolysis of sea cucumber body wall [2] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 100 mg/mL ( 504.49 mM ; Need ultrasonic)
H 2 O : 2 mg/mL ( 10.09 mM ; ultrasonic and warming and heat to 60°C)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 5.0449 mL | 25.2245 mL | 50.4490 mL |
| 5 mM | 1.0090 mL | 5.0449 mL | 10.0898 mL |
| 10 mM | 0.5045 mL | 2.5224 mL | 5.0449 mL |
References
- [1] Guan NanMu, et al. Synergistic inhibition between o-phenanthroline and chloride ion on cold rolled steel corrosion in phosphoric acid. Materials Chemistry and Physics Volume 86, Issue 1, 15 July 2004, Pages 59-68.
- [2] Zi-Qiang Liu, et al. The role of matrix metalloprotease (MMP) to the autolysis of sea cucumber (Stichopus japonicus). J Sci Food Agric. 2019 Oct;99(13):5752-5759.
Synonyms