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[CAS NO. 526-08-9] Sulfaphenazole
| Ships within | Stock | Price | Qty | Total |
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| Catalog: | HY-B1218 |
| Brand: | MCE |
| CAS: | 526-08-9 |
Overview
| MDL | MFCD00057226 |
|---|---|
| Molecular Weight | 314.36 |
| Molecular Formula | C15H14N4O2S |
| SMILES | O=S(C1=CC=C(N)C=C1)(NC2=CC=NN2C3=CC=CC=C3)=O |
9 Publications Citing Use of MCE
- [1]Carbohyd Polym. 2021 Feb 1;253:117255.
- [2]Chemosphere. 2021, 131347.
- [3]Food Chem Toxicol. 2022 Sep 15;113431.
- [4]J Agric Food Chem. 2019 Jul 24;67(29):8243-8252.
- [5]J Agric Food Chem. 2019 Apr 17;67(15):4328-4336.
- [6]AAPS J. 2021 Jun 28;23(4):91.
- [7]J Ethnopharmacol. 2019 May 10;235:309-319.
- [8]Chem Res Toxicol. 2019 Oct;18(4):3025-3031.
- [9]ACS Appl Nano Mater. July 1, 2022.
Summary
Sulfaphenazole is a specific inhibitor of CYP2C9 which blocks atherogenic and pro-inflammatory effects of linoleic acid (increase in oxidative stress and activation of AP-1) mediated by CYP2C9. Acts as an antibacterial and antimicrobial.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : ≥ 100 mg/mL ( 318.11 mM )
* "≥" means soluble, but saturation unknown.
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 3.1811 mL | 15.9053 mL | 31.8107 mL |
| 5 mM | 0.6362 mL | 3.1811 mL | 6.3621 mL |
| 10 mM | 0.3181 mL | 1.5905 mL | 3.1811 mL |
References
- [1] Chimalakonda KC, et al. Sulfaphenazole and α-naphthoflavone attenuate the metabolism of the synthetic cannabinoids JWH-018 and AM2201 found in K2/spice. Drug Metab Lett. 2013 Mar;7(1):34-8.
- [2] Hama S, et al. Effects of sulfaphenazole after collagenase-induced experimental intracerebral hemorrhage in rats. Biol Pharm Bull. 2012;35(10):1849-53.
- [3] BROWNE SG.Trial of a long-acting sulfonamide sulfaphenazole (Orisul, Ciba), in the treatment of leprosy. Int J Lepr. 1961 Oct-Dec;29:502-5.
Synonyms
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