[CAS NO. 528-58-5] Cyanidin Chloride

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PRODUCTS SPECIFICATIONS [528-58-5]

Catalog

HY-N0499

Brand

MCE

CAS

528-58-5

DESCRIPTION [528-58-5]

Overview

MDL	MFCD00017582
Molecular Weight	322.70
Molecular Formula	C15H11ClO6
SMILES	OC1=CC2=[O+]C(C3=CC=C(O)C(O)=C3)=C(O)C=C2C(O)=C1.[Cl-]

For research use only. We do not sell to patients.

2 Publications Citing Use of MCE

Summary

Cyanidin Chloride (IdB 1027), a subclass of anthocyanin, displays antioxidant and anti-carcinogenesis properties. Cyanidin Chloride (IdB 1027) inhibits osteoclast formation, hydroxyapatite resorption, and receptor activator of NF-κB ligand (RANKL)-induced osteoclast marker gene expression ^[1] .

In Vitro

Cyanidin Chloride (IdB 1027) inhibits receptor activator of NF-κB ligand (RANKL)-induced NF-κB activation, suppresses the degradation of IκB-α and attenuates the phosphorylation of extracellular signal-regulated kinases (ERK). Cyanidin Chloride (IdB 1027) abrogates RANKL-induced calcium oscillations, the activation of nuclear factor of activated T cells calcineurin-dependent 1 (NFATc1), and the expression of c-Fos ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Cyanidin Chloride (IdB 1027) protects against OVX-induced bone loss in OVX-induced osteoporosis mouse model ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 25 mg/mL ( 77.47 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.0989 mL	15.4943 mL	30.9885 mL
5 mM	0.6198 mL	3.0989 mL	6.1977 mL
10 mM	0.3099 mL	1.5494 mL	3.0989 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (7.75 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (7.75 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Cheng J, et al. Cyanidin Chloride inhibits ovariectomy-induced osteoporosis by suppressing RANKL-mediated osteoclastogenesis and associated signaling pathways. J Cell Physiol. 2018 Mar;233(3):2502-2512.

Synonyms

1-Benzopyrylium, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-, chloride (1:1)

Flavylium, 3,3′,4′,5,7-pentahydroxy-, chloride

1-Benzopyrylium, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-, chloride

Cyanidol

Cyanidin

Cyanidin chloride

3,3′,4′,5,7-Pentahydroxyflavylium chloride

3,3′,4′,5,7-Pentahydroxy-2-phenylbenzopyrylium chloride

2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopyrylium chloride

Cyanidol chloride

IdB 1027

Cyanidine