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[CAS NO. 52806-53-8] Hydroxyflutamide
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-W013272 |
| Brand: | MCE |
| CAS: | 52806-53-8 |
Overview
| MDL | MFCD00563126 |
|---|---|
| Molecular Weight | 292.21 |
| Molecular Formula | C11H11F3N2O4 |
| SMILES | CC(C)(O)C(NC1=CC=C([N+]([O-])=O)C(C(F)(F)F)=C1)=O |
Summary
Hydroxyflutamide (HF), an active metabolite of Flutamide, is a potent androgen receptor antagonist ( IC 50 =700 nM). Hydroxyflutamide can be used for the research of prostate cancer [1] [2] .
IC50 & Target
IC50: 700 nM (androgen receptor) [1]
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date | Phase |
|---|---|---|---|---|
| NCT02023398 | BTL Industries Ltd. |
Circumferential Reduction|Waist Circumferential Reduction
|
September 2013 | Not Applicable |
| NCT03244761 | Capital Medical University |
Tracheostomy
|
July 1, 2017 | |
| NCT04089410 | I.M. Sechenov First Moscow State Medical University |
Hypoxia, Altitude|Exercise Tolerance|Metabolic Disturbance|Quality of Life
|
January 14, 2019 | Not Applicable |
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 100 mg/mL ( 342.22 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 3.4222 mL | 17.1110 mL | 34.2220 mL |
| 5 mM | 0.6844 mL | 3.4222 mL | 6.8444 mL |
| 10 mM | 0.3422 mL | 1.7111 mL | 3.4222 mL |
References
Synonyms
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