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[CAS NO. 53994-73-3] Cefaclor
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-B0198 |
| Brand: | MCE |
| CAS: | 53994-73-3 |
Overview
| MDL | MFCD00151471 |
|---|---|
| Molecular Weight | 367.81 |
| Molecular Formula | C15H14ClN3O4S |
| SMILES | O=C(C(N12)=C(Cl)CS[C@]2([H])[C@H](NC([C@H](N)C3=CC=CC=C3)=O)C1=O)O |
Summary
Cefaclor is a well-absorbed orally active cephalosporin antibiotic . Cefaclor can specifically bind to specific for penicillin-binding protein 3 (PBP3) . Cefaclor can be used for the research kinds of infections caused by bacteria, such as respiratory tract infections, bacterial bronchitis, pharyngitis and skin infections [1] [2] [3] .
IC50 & Target
|
β-lactam
|
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date | Phase |
|---|---|---|---|---|
| NCT05398679 | Fundacion Clinic per a la Recerca Biomédica |
Endocarditis Infective
|
June 1, 2022 | Phase 4 |
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 18.5 mg/mL ( 50.30 mM ; Need ultrasonic and warming)
H 2 O : 3.85 mg/mL ( 10.47 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.7188 mL | 13.5940 mL | 27.1880 mL |
| 5 mM | 0.5438 mL | 2.7188 mL | 5.4376 mL |
| 10 mM | 0.2719 mL | 1.3594 mL | 2.7188 mL |
-
1.
Add each solvent one by one: PBS
Solubility: 3.33 mg/mL (9.05 mM); Clear solution; Need ultrasonic and warming and heat to 60°C
References
- [1] Chambers HF, et al. Characterization of penicillin-binding protein 2 of Staphylococcus aureus: deacylation reaction and identification of two penicillin-binding peptides. Antimicrob Agents Chemother. 1992 Mar;36(3):656-61.
- [2] B R Meyers, et al. Cefaclor revisited. Clin Ther. 2000 Feb;22(2):154-66.
- [3] H Sourgens, et al. Pharmacokinetic profile of cefaclor. Int J Clin Pharmacol Ther
Synonyms
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