[CAS NO. 58717-24-1] A2315A

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PRODUCTS SPECIFICATIONS [58717-24-1]

Catalog

HY-118593

Brand

MCE

CAS

58717-24-1

DESCRIPTION [58717-24-1]

Overview

MDL	-
Molecular Weight	503.59
Molecular Formula	C26H37N3O7
SMILES	O=C(N[C@@H]1C)C2=COC(C[C@@H](C[C@@H](/C=C(\C=C\CNC(/C=C\[C@H]([C@H](OC1=O)C(C)C)C)=O)C)O)O)=N2

For research use only. We do not sell to patients.

Summary

A2315A (Madumycin II) is an alanine-containing streptogramin A antibiotic . A2315A is a potent peptidyl transferase center (PTC) inhibitor. A2315A inhibits the ribosome prior to the first cycle of peptide bond formation ^[1] .

Source

A.philippinensis

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References

[1] Osterman IA, et, al. Madumycin II inhibits peptide bond formation by forcing the peptidyl transferase center into an inactive state. Nucleic Acids Res. 2017 Jul 7;45(12):7507-7514.