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[CAS NO. 59703-84-3] Piperacillin sodium
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-B1286 |
| Brand: | MCE |
| CAS: | 59703-84-3 |
Overview
| MDL | MFCD00917471 |
|---|---|
| Molecular Weight | 539.54 |
| Molecular Formula | C23H26N5NaO7S |
| SMILES | O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC([C@H](NC(N3C(C(N(CC)CC3)=O)=O)=O)C4=CC=CC=C4)=O)N1C2=O)O[Na] |
3 Publications Citing Use of MCE
Summary
Piperacillin sodium is a broad-spectrum β-lactam antibiotic .
IC50 & Target
|
β-lactam
|
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date | Phase |
|---|---|---|---|---|
| NCT05608564 | University of Belgrade |
Periodontitis
|
January 17, 2022 | Not Applicable |
| NCT02817347 | Yuhan Corporation |
Otitis Media|Otorrhea
|
June 2016 | Phase 1|Phase 2 |
| NCT05355350 | Rambam Health Care Campus|The Chaim Sheba Medical Center|Rabin Medical Center|Hadassah Medical Organization |
Beta Lactam Resistant Bacterial Infection|Enterobacteriaceae Infections|Bacteremia
|
July 1, 2022 | Phase 4 |
| NCT01760109 | Xiangbei Welman Pharmaceutical Co., Ltd |
Respiratory Tract Infections|Urinary Tract Infections
|
July 2011 | Phase 4 |
| NCT03765645 | Institute of Liver and Biliary Sciences, India |
Antibiotic Prophylaxis|Postoperative Infection
|
October 4, 2018 | Not Applicable |
| NCT04530045 | Central Hospital, Nancy, France |
Critical Illness|Antibiotic Toxicity|Sepsis|Septic Shock
|
May 2, 2018 | |
| NCT01714557 | Chinese PLA General Hospital |
Neutropenia|Hematopoietic Stem Cell Transplantation
|
September 2012 | Not Applicable |
| NCT03932123 | Shandong University|Tianjin Central Hospital of Gynecology Obstetrics|Shandong Provincial Hospital|Qianfoshan Hospital |
Early Onset Neonatal Sepsis
|
May 5, 2019 | |
| NCT02493764 | Merck Sharp & Dohme LLC |
Bacterial Pneumonia
|
November 24, 2015 | Phase 3 |
| NCT03990467 | Hospices Civils de Lyon |
Septic Shock|Sepsis|Sepsis Syndrome
|
January 28, 2021 | Not Applicable |
| NCT05060419 | Qilu Pharmaceutical Co., Ltd. |
Complicated Urinary Tract Infection|Acute Pyelonephritis
|
October 8, 2021 | Phase 2 |
| NCT03628300 | Centre Hospitalier Universitaire, Amiens |
Neurotoxicity|Sepsis
|
January 1, 2017 | |
| NCT02473263 | Assistance Publique - Hôpitaux de Paris |
Severe Septic Syndrome (Severe Sepsis and Septic Shock) Diagnosed and Treated by Mobile Intensive Care Unit
|
May 9, 2016 | Phase 3 |
| NCT04948463 | Murdoch Childrens Research Institute |
Febrile Neutropenia
|
November 15, 2021 | Phase 4 |
| NCT01697059 | Rhode Island Hospital |
Acute Appendicitis
|
September 2012 | Not Applicable |
| NCT00389987 | Merck Sharp & Dohme LLC |
Complicated Intra-Abdominal Infections
|
September 2001 | Phase 3 |
| NCT01805856 | Ito Hospital |
Thyroid Disease|Parathyroid Disease
|
November 2010 | Not Applicable |
| NCT03685084 | Allecra |
Healthy
|
October 10, 2013 | Phase 1 |
| NCT01667094 | The Alfred |
Cystic Fibrosis
|
September 2012 | Phase 4 |
| NCT00003805 | European Organisation for Research and Treatment of Cancer - EORTC |
Bone Marrow Suppression|Fever, Sweats, and Hot Flashes|Infection|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Unspecified Adult Solid Tumor, Protocol Specific|Unspecified Childhood Solid Tumor, Protocol Specific
|
November 1997 | Phase 3 |
| NCT01198925 | University Hospital, Ghent |
Infectious Disease
|
September 23, 2010 | Phase 4 |
| NCT00894439 | Wyeth is now a wholly owned subsidiary of Pfizer |
Healthy Subjects
|
May 2009 | Phase 1 |
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL ( 185.34 mM ; Need ultrasonic)
H 2 O : ≥ 100 mg/mL ( 185.34 mM )
* "≥" means soluble, but saturation unknown.
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 1.8534 mL | 9.2672 mL | 18.5343 mL |
| 5 mM | 0.3707 mL | 1.8534 mL | 3.7069 mL |
| 10 mM | 0.1853 mL | 0.9267 mL | 1.8534 mL |
-
1.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (185.34 mM); Clear solution; Need ultrasonic
-
2.
-
3.
Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)
Solubility: ≥ 2.5 mg/mL (4.63 mM); Clear solution
-
4.
Add each solvent one by one: 10% DMSO >> 90% corn oil
Solubility: ≥ 2.5 mg/mL (4.63 mM); Clear solution
References
- [1] Tan JS, et al. Antipseudomonal penicillins. Med Clin North Am. 1995 Jul;79(4):679-93.
- [2] Lau WK, et al. Randomized, open-label, comparative study of piperacillin-tazobactam administered by continuous infusion versus intermittent infusion for treatment of hospitalized patients with complicated intra-abdominal infection. Antimicrob Agents Chemother. 2006 Nov;50(11):3556-61.
- [3] Fu KP, et al. Piperacillin, a new penicillin active against many bacteria resistant to other penicillins. Antimicrob Agents Chemother. 1978 Mar;13(3):358-67.
Synonyms
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