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[CAS NO. 59865-13-3] Cyclosporin A

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COA

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Catalog:	HY-B0579
Brand:	MCE
CAS:	59865-13-3

Overview

MDL	MFCD00274558
Molecular Weight	1202.61
Molecular Formula	C62H111N11O12
SMILES	C/C=C/C[C@H]([C@@H](O)[C@@]1(N(C)C([C@]([H])(C(C)C)N(C)C([C@H](CC(C)C)N(C)C([C@]([H])(CC(C)C)N(C)C([C@@H](C)NC([C@H](C)NC([C@@H](N(C([C@@]([H])(NC([C@@H](N(C(CN(C([C@@H](NC1=O)CC)=O)C)=O)C)CC(C)C)=O)C(C)C)=O)C)CC(C)C)=O)=O)=O)=O)=O)=O)[H])C

For research use only. We do not sell to patients.

71 Publications Citing Use of MCE

[1]Adv Sci (Weinh). 2023 Jan 15;e2203869.
[2]Adv Sci (Weinh). 2021 Jan 6;8(5):2002738.
[3]Nat Commun. 2021 May 18;12(1):2915.
[4]Redox Biol. 2022 Aug;54:102355.
[5]Arthritis Rheumatol. 2022 Sep 3.
[6]Proc Natl Acad Sci U S A. 2021 Jan 12;118(2):e2009539118.
[7]Bioact Mater. 2023, 23：300-313
[8]Cell Rep. 2022 Mar 8;38(10):110486.
[9]Cell Rep. 2021 Nov 30;37(9):110069.
[10]Cell Rep. 2021 Jul 20;36(3):109398.
[11]Cell Rep. 2021 Apr 6;35(1):108959.
[12]Clin Transl Med. 2022 Aug;12(8):e1002.
[13]Environ Sci Technol. 2017 Dec 5;51(23):13938-13948.
[14]Cell Chem Biol. 2022 Aug 17;S2451-9456(22)00277-X.
[15]Br J Pharmacol. 2021 Jun;178(11):2305-2323.
[16]J Invest Dermatol. 29 October 2022.
[17]Cell Death Dis. 2021 Apr 1;12(4):336.
[18]Cell Death Dis. 2021 Apr 20;12(5):413.
[19]Cell Death Dis. 2018 May 22;9(6):598.
[20]Exp Mol Med. 2022 Feb;54(2):129-142.
[21]Aging Dis. 2022 Oct 1;13(5):1546-1561.
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[23]Am J Respir Cell Mol Biol. 2019 Sep;61(3):355-366.
[24]Neurobiol Dis. 2019 Sep;129:44-55.
[25]Int J Biol Macromol. 2020 May 1;150:261-280.
[26]Oxid Med Cell Longev. 2022 Sep 1;2022:4722647.
[27]Antioxidants (Basel). 2022 Jul 26;11(8):1455.
[28]Biochem Pharmacol. 2022 Jul 6;115164.
[29]Biochem Pharmacol. 4 June 2022, 115116.
[30]Biochem Pharmacol. 2021 Dec 28;114904.
[31]J Immunol. 2022 Apr 1;208(7):1616-1631.
[32]J Immunol. 2020 Feb 1;204(3):569-585.
[33]Ecotox Environ Safe. 2020 Oct 1;202:110901.
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[35]Food Chem Toxicol. 2022 Jan 6;112811.
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[37]Biomed Pharmacother. 2022 May 10;151:113092.
[38]Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Feb;1865(2):158531.
[39]ACS Chem Neurosci. 2021 Sep 9.
[40]Front Pharmacol. 2021 Oct 15;12:733805.
[41]J Neurochem. 2021 Aug 18.
[42]Int Immunopharmacol. 2018 Jul 5;62:67-76.
[43]PLoS Negl Trop Dis. 2019 Aug 20;13(8):e0007681.
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[45]Chem Biol Interact. 2022 Jun 1;110003.
[46]Life Sci. 2020 Nov 15;261:118351.
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[48]Front Med. 2021 Jun;15(3):472-485.
[49]Am J Transl Res. 2018 Aug 15;10(8):2435-2444.
[50]Ann Transl Med. 2020 Jul;8(14):858.
[51]Eur J Pharmacol. 2021 Nov 5;174617.
[52]Placenta. 12 November 2021.
[53]Neural Regen Res. 2023 Apr;18(4):849-855.
[54]Int J Mol Med. 2020 Aug;46(2):663-674.
[55]Phytochemistry. 2021 Apr 27;187:112780.
[56]Neurotox Res. 2021 Feb 13.
[57]Biochem Biophys Res Commun. 2019 Apr 30;512(2):269-275.
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[67]STAR Protoc. 17 June 2022, 101423.
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[71]J Clin Toxicol 2014, 4:5

Summary

Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of calcineurin with an IC ₅₀ of 5 nM ^[3] . Cyclosporin A also inhibits CD11a/CD18 adhesion ^[8] .

IC50 & Target

IC50: 7 nM (calcineurin)

In Vitro

Cyclosporin A is able to bind with the cyclophilin in T cells ^[1] . Cyclosporin A works by forming a Cyclophilin-Cyclosporin A complex to inhibit calcineurin ^[2] . Cyclosporin A inhibits calcineurin in stimulated cells with an IC ₅₀ value of 7 nM ^[3] . Cyclosporin A suppresses the nuclear translocation of NF-AT ^[4] . Cyclosporin A shows an effect on mitochondria via preventing the MTP from opening with an IC ₅₀ of 39 nM ^[5] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Cyclosporin A has immunosuppressive activity, and is active via parenteral and p.o. administration in mice, rat and guinea pigs ^[6] . Cyclosporin A can be used in organ transplantation to prevent rejection ^[7] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase
NCT04412785	University of Pennsylvania	COVID-19	June 30, 2020	Phase 1
NCT01370343	Pfizer	Healthy\|Drug Interaction	July 2011	Phase 1
NCT00548301	Sirion Therapeutics, Inc.	Dry Eye Syndromes		Phase 3
NCT02013791	Allergan	Dry Eye Syndromes	April 29, 2014	Phase 2
NCT00000936	National Institute of Allergy and Infectious Diseases (NIAID)	Kidney Transplantation	November 1999	Phase 3
NCT02660684	Astellas Pharma Korea, Inc.\|Astellas Pharma Inc	Graft Versus Host Disease	February 2008	Phase 4
NCT03209219	Peking Union Medical College Hospital	Behçet Disease\|Uveitis	June 30, 2017	Phase 3
NCT01650545	University of Maryland\|University of Maryland, Baltimore	Disorder Related to Lung Transplantation\|Bronchiolitis Obliterans\|Decreased Immunologic Activity\|Chronic Rejection of Lung Transplant	July 2012	Phase 1\|Phase 2
NCT00003662	Roswell Park Cancer Institute\|National Cancer Institute (NCI)	Graft Versus Host Disease\|Leukemia\|Myelodysplastic Syndromes\|Thymic Carcinoma	August 1998	Phase 2
NCT00118352	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Acute Undifferentiated Leukemia\|Adult Acute Lymphoblastic Leukemia in Remission\|Adult Acute Myeloid Leukemia in Remission\|Adult Nasal Type Extranodal NK+T-cell Lymphoma\|Anaplastic Large Cell Lymphoma\|Angioimmunoblastic T-cell Lymphoma\|Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative\|Childhood Acute Lymphoblastic Leukemia in Remission\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Burkitt Lymphoma\|Childhood Chronic Myelogenous Leukemia\|Childhood Diffuse Large Cell Lymphoma\|Childhood Immunoblastic Large Cell Lymphoma\|Childhood Myelodysplastic Syndromes\|Childhood Nasal Type Extranodal NK+T-cell Lymphoma\|Chronic Myelomonocytic Leukemia\|Chronic Phase Chronic Myelogenous Leukemia\|Cutaneous B-cell Non-Hodgkin Lymphoma\|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue\|Hepatosplenic T-cell Lymphoma\|Intraocular Lymphoma\|Juvenile Myelomonocytic Leukemia\|Mast Cell Leukemia\|Myelodysplastic+Myeloproliferative Neoplasm, Unclassifiable\|Nodal Marginal Zone B-cell Lymphoma\|Noncutaneous Extranodal Lymphoma\|Peripheral T-cell Lymphoma\|Previously Treated Myelodysplastic Syndromes\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Adult Burkitt Lymphoma\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent Adult Diffuse Mixed Cell Lymphoma\|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma\|Recurrent Adult Grade III Lymphomatoid Granulomatosis\|Recurrent Adult Hodgkin Lymphoma\|Recurrent Adult Immunoblastic Large Cell Lymphoma\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Adult T-cell Leukemia+Lymphoma\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Recurrent Childhood Anaplastic Large Cell Lymphoma\|Recurrent Childhood Grade III Lymphomatoid Granulomatosis\|Recurrent Childhood Large Cell Lymphoma\|Recurrent Childhood Lymphoblastic Lymphoma\|Recurrent Childhood Small Noncleaved Cell Lymphoma\|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Grade 3 Follicular Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Mycosis Fungoides+Sezary Syndrome\|Recurrent Small Lymphocytic Lymphoma\|Recurrent+Refractory Childhood Hodgkin Lymphoma\|Refractory Chronic Lymphocytic Leukemia\|Refractory Hairy Cell Leukemia\|Refractory Multiple Myeloma\|Relapsing Chronic Myelogenous Leukemia\|Secondary Myelodysplastic Syndromes\|Small Intestine Lymphoma\|Splenic Marginal Zone Lymphoma\|Testicular Lymphoma\|Waldenström Macroglobulinemia	March 2005	Phase 2
NCT04195633	Fred Hutchinson Cancer Center\|medac GmbH	Acute Leukemia\|Acute Lymphoblastic Leukemia\|Acute Myeloid Leukemia\|Adult Diffuse Large Cell Lymphoma\|Anaplastic Large Cell Lymphoma\|Burkitt Lymphoma\|Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Chronic Myelomonocytic Leukemia\|Hodgkin Lymphoma\|Lymphoblastic Lymphoma\|Lymphoplasmacytic Lymphoma\|Mantle Cell Lymphoma\|Mixed Phenotype Acute Leukemia\|Myelodysplastic Syndrome\|Prolymphocytic Leukemia\|Refractory Chronic Lymphocytic Leukemia\|Refractory Follicular Lymphoma\|Refractory Marginal Zone Lymphoma\|Refractory Small Lymphocytic Lymphoma	January 25, 2021	Phase 2
NCT04775303	Yonsei University	Moderate to Severe Dry Eye	September 25, 2020	Phase 4
NCT01514968	Hoffmann-La Roche	Healthy Volunteer	December 2011	Phase 1
NCT00481832	Stanford University	Lymphoma, Non-Hodgkin	January 2007	Phase 2
NCT00157014	Astellas Pharma Inc\|Astellas Pharma Canada, Inc.	Heart Diseases\|Heart Transplantation	May 10, 2004	Phase 3
NCT00348335	Ophthalmic Consultants of Long Island\|Allergan	Rosacea	June 2006	Phase 4
NCT00024128	AIDS Malignancy Consortium\|National Cancer Institute (NCI)	Lymphoma	August 2001	Phase 2
NCT00321958	University of Maryland, Baltimore\|CSA Medical, Inc.	Barrett Esophagus\|Esophageal Neoplasms\|Deglutition Disorders\|GERD\|Neoplasm	April 2006
NCT00959231	Cancer Research UK\|National Cancer Institute (NCI)	Hematopoietic+Lymphoid Cancer	January 2009	Phase 2
NCT02281370	GlaxoSmithKline	Purpura, Thrombocytopenic, Idiopathic	November 5, 2014	Phase 1
NCT00919542	London School of Hygiene and Tropical Medicine\|Homes and Hospitals of St Giles\|Alert Hospital, Ethiopia\|Armauer Hansen Research Institute, Ethiopia	Leprosy	July 2010	Phase 2
NCT00816413	University of Nebraska\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Leukemia\|Lymphoma\|Myelodysplastic Syndromes\|Nonmalignant Neoplasm	September 2008	Phase 1\|Phase 2
NCT00419926	Novartis	Kidney Transplantation	December 2006	Phase 4
NCT02121847	Allergan	Dry Eye Syndromes	April 3, 2014	Phase 4
NCT00005898	University of Minnesota\|Office of Rare Diseases (ORD)	Fanconi´s Anemia	February 2000	Phase 1\|Phase 2
NCT03237936	Santen SAS	Keratitis	March 28, 2017	Phase 4
NCT00948727	Assistance Publique - Hôpitaux de Paris\|Agence de La Biomédecine	Hematopoietic Stem Cell Transplantation\|Graft Versus Host Disease	January 2004	Phase 2
NCT01342887	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Adult Acute Megakaryoblastic Leukemia (M7)\|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)\|Adult Acute Monoblastic Leukemia (M5a)\|Adult Acute Monocytic Leukemia (M5b)\|Adult Acute Myeloblastic Leukemia With Maturation (M2)\|Adult Acute Myeloblastic Leukemia Without Maturation (M1)\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Adult Acute Myelomonocytic Leukemia (M4)\|Adult Erythroleukemia (M6a)\|Adult Pure Erythroid Leukemia (M6b)\|Recurrent Adult Acute Myeloid Leukemia	April 2011	Phase 1\|Phase 2
NCT00185692	Stanford University	Blood Cancer\|Leukemia\|Graft Versus Host Disease\|Malignancy\|CLL\|NHL\|Hodgkin´s Disease\|MDS	August 2000	Phase 2
NCT01252667	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Acute Myeloid Leukemia	January 25, 2011	Phase 2
NCT00795132	University of Utah	Acute Leukaemia\|Chronic Disease\|Leukemia\|Myelodysplasia\|Lymphoma	April 2004	Phase 2
NCT03128034	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome\|Acute Myeloid Leukemia\|Chronic Myelomonocytic Leukemia\|Myelodysplastic Syndrome With Excess Blasts\|Recurrent Acute Myeloid Leukemia\|Refractory Acute Lymphoblastic Leukemia\|Recurrent Acute Lymphoblastic Leukemia\|Recurrent Mixed Phenotype Acute Leukemia\|Refractory Acute Myeloid Leukemia\|Refractory Mixed Phenotype Acute Leukemia\|Mixed Phenotype Acute Leukemia	October 24, 2017	Phase 1\|Phase 2
NCT00096161	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Acute Myeloid Leukemia\|Chronic Lymphocytic Leukemia\|Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Graft Versus Host Disease\|Hodgkin Lymphoma\|Myelodysplastic+Myeloproliferative Neoplasm\|Non-Hodgkin Lymphoma\|Plasma Cell Myeloma\|Waldenstrom Macroglobulinemia	May 2003	Phase 2
NCT00789308	National Institute of Allergy and Infectious Diseases (NIAID)\|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)\|Clinical Islet Transplantation Consortium	Diabetes Mellitus, Type I	July 11, 2008	Phase 2
NCT03083782	Thomas Jefferson University\|Bristol-Myers Squibb	Venous Thromboembolism\|Pharmacokinetics\|Healthy	April 18, 2017	Phase 1
NCT01392989	Everett Meyer\|Stanford University	Neural Tube Defects\|Anemia\|Leukemia, Myeloid\|Bone Marrow Transplant Failure\|Myelodysplastic Syndromes (MDS)\|Myeloproliferative Disorders	March 2011	Phase 2
NCT00008151	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Leukemia\|Myelodysplastic Syndromes	October 2000	Phase 2
NCT00717418	Allergan	Keratoconjunctivitis Sicca	September 2004
NCT00119340	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Leukemia	April 2005	Phase 1\|Phase 2
NCT05600426	Boston Children´s Hospital\|Center for International Blood and Marrow Transplant Research\|National Institutes of Health (NIH)\|National Heart, Lung, and Blood Institute (NHLBI)\|North American Pediatric Aplastic Anemia Consortium\|Pediatric Transplantation and Cellular Therapy Consortium\|Blood and Marrow Transplant Clinical Trials Network	Severe Aplastic Anemia	December 2022	Phase 3
NCT01552629	Novartis Pharmaceuticals\|Novartis	Atopic Dermatitis	January 5, 2012	Phase 2
NCT01446484	Pirogov Russian National Research Medical University\|Russian Academy of Medical Sciences	End-Stage Renal Disease\|Kidney Failure	October 2011	Phase 1\|Phase 2
NCT01786018	Azienda Ospedaliera San Giovanni Battista	B-cell Lymphoma Refractory	February 2013	Phase 2
NCT02176733	University Hospital, Angers	Leber Hereditary Optic Neuropathy	July 2011	Phase 2
NCT00105235	National Institute of Allergy and Infectious Diseases (NIAID)\|Immune Tolerance Network (ITN)	Liver Disease\|Liver Transplantation	June 2005	Phase 2
NCT02091414	Hoffmann-La Roche	Heart Transplantation	August 2006	Phase 3
NCT00054353	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Refractory Multiple Myeloma	October 2002	Phase 1\|Phase 2
NCT00777933	Samsung Medical Center	Kidney Transplantation\|Living Donors	July 2000	Not Applicable
NCT00002785	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	July 1996	Phase 2
NCT00003414	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins\|National Cancer Institute (NCI)	Graft Versus Host Disease\|Lymphoma	October 1997	Phase 3
NCT00003661	Roswell Park Cancer Institute	Graft Versus Host Disease\|Leukemia\|Lymphoma\|Myelodysplastic Syndromes\|Neuroblastoma	June 1998	Phase 2
NCT05131152	Zhongshan Ophthalmic Center, Sun Yat-sen University	Dry Eye	December 1, 2021	Not Applicable
NCT00899847	Stanford University	Transplantation, Homologous\|Transplantation, Autologous\|Multiple Myeloma\|Blood and Marrow Transplant (BMT)	May 2009	Phase 2
NCT04813653	Tel-Aviv Sourasky Medical Center\|Weizmann Institute of Science	Multiple Myeloma in Relapse\|Multiple Myeloma, Refractory	April 18, 2021	Phase 1
NCT04692376	Nanfang Hospital of Southern Medical University\|Sun Yat-sen University\|Xinqiao Hospital, Army Medical University\|Peking University People´s Hospital	Chronic Graft-versus-host Disease	January 10, 2021	Phase 2
NCT00891306	Amsterdam Molecular Therapeutics\|The Clinical Trial Company	Familial Lipoprotein Lipase Deficiency	February 2009	Phase 2\|Phase 3
NCT00005940	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)	October 1999	Phase 2
NCT01175785	Nohla Therapeutics, Inc.\|National Heart, Lung, and Blood Institute (NHLBI)\|National Cancer Institute (NCI)\|Fred Hutchinson Cancer Center	Accelerated Phase Chronic Myelogenous Leukemia\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Childhood Acute Lymphoblastic Leukemia in Remission\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Chronic Myelogenous Leukemia\|Childhood Myelodysplastic Syndromes\|Chronic Phase Chronic Myelogenous Leukemia\|de Novo Myelodysplastic Syndromes\|Previously Treated Myelodysplastic Syndromes\|Refractory Anemia\|Refractory Anemia With Excess Blasts\|Refractory Anemia With Excess Blasts in Transformation\|Relapsing Chronic Myelogenous Leukemia\|Secondary Myelodysplastic Syndromes	August 2010	Phase 2
NCT00006055	Fairview University Medical Center\|Office of Rare Diseases (ORD)	Purpura, Schoenlein-Henoch\|Graft Versus Host Disease\|Anemia, Hemolytic, Autoimmune\|Rheumatoid Arthritis\|Churg-Strauss Syndrome\|Hypersensitivity Vasculitis\|Wegener´s Granulomatosis\|Systemic Lupus Erythematosus\|Giant Cell Arteritis\|Pure Red Cell Aplasia\|Juvenile Rheumatoid Arthritis\|Polyarteritis Nodosa\|Autoimmune Thrombocytopenic Purpura\|Takayasu Arteritis	March 2000	Not Applicable
NCT00007787	National Institute of Allergy and Infectious Diseases (NIAID)	Kidney Transplantation\|Chronic Allograft Nephropathy	April 2000	Not Applicable
NCT00309842	Masonic Cancer Center, University of Minnesota	Acute Myeloid Leukemia\|Acute Lymphocytic Leukemia\|Chronic Myelogenous Leukemia\|Myelofibrosis\|MDS\|Refractory Anemia\|Chronic Lymphocytic Leukemia\|Prolymphocytic Leukemia\|Non-Hodgkin´s Lymphoma\|Leukemia\|Lymphoma\|Multiple Myeloma\|Myelodysplastic Syndromes	July 28, 2005	Phase 2
NCT00983931	Mutual Pharmaceutical Company, Inc.	Pharmacokinetics\|Healthy	August 2008	Phase 1
NCT00974142	Michael Donahoe\|National Heart, Lung, and Blood Institute (NHLBI)\|University of Pittsburgh	Chronic Obstructive Pulmonary Disease	September 2009	Phase 1\|Phase 2
NCT00903188	University Hospital, Antwerp\|Novartis Pharmaceuticals\|Erasme University Hospital\|University Hospital, Ghent\|University of Liege\|Universitair Ziekenhuis Brussel	Renal Transplantation	October 2008	Phase 4
NCT04304820	National Heart, Lung, and Blood Institute (NHLBI)\|National Institutes of Health Clinical Center (CC)	Severe Aplastic Anemia	May 7, 2020	Phase 2
NCT01503242	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Plasma Cell Myeloma\|Refractory Plasma Cell Myeloma	January 9, 2012	Phase 1
NCT00255684	University of Rochester	Chronic Myeloproliferative Disorders\|Graft Versus Host Disease\|Leukemia\|Lymphoma\|Multiple Myeloma\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Neoplasms	December 2003	Not Applicable
NCT00185640	Stanford University	Blood Cancer\|Leukemia	March 2003	Phase 2
NCT01231412	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Acute Myeloid Leukemia\|Aggressive Non-Hodgkin Lymphoma\|Chronic Lymphocytic Leukemia\|Diffuse Large B-Cell Lymphoma\|Hematopoietic and Lymphoid Cell Neoplasm\|Indolent Non-Hodgkin Lymphoma\|Mantle Cell Lymphoma\|Myelodysplastic Syndrome\|Myeloproliferative Neoplasm\|Prolymphocytic Leukemia\|Recurrent Chronic Lymphocytic Leukemia\|Recurrent Plasma Cell Myeloma\|Refractory Chronic Lymphocytic Leukemia\|Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Refractory Hodgkin Lymphoma\|Small Lymphocytic Lymphoma\|T-Cell Chronic Lymphocytic Leukemia\|Waldenstrom Macroglobulinemia	November 2010	Phase 3
NCT00317785	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Leukemia\|Lymphoma\|Myelodysplastic Syndromes	May 2005	Phase 2
NCT00793572	Fred Hutchinson Cancer Center\|Millennium Pharmaceuticals, Inc.\|National Cancer Institute (NCI)	Refractory Plasma Cell Myeloma	October 2008	Phase 2
NCT00578643	Baylor College of Medicine	Chronic Granulomatous Disease	March 2004	Phase 2
NCT01231841	The Cleveland Clinic	Aplastic Anemia	March 2005	Phase 2
NCT00005988	Dana-Farber Cancer Institute\|National Cancer Institute (NCI)	Graft Versus Host Disease\|Leukemia\|Lymphoma\|Myelodysplastic Syndromes\|Myeloma	February 2000	Phase 1
NCT01494597	Astellas Pharma Inc\|Basilea Pharmaceutica International Ltd	Healthy	November 2011	Phase 1
NCT01598987	Novartis Pharmaceuticals\|Novartis	Renal Function\|Liver Transplant	October 2012	Phase 3
NCT00003056	Baxalta now part of Shire\|Takeda	Leukemia\|Lymphoma\|Graft Versus Host Disease	April 1, 1997	Phase 3
NCT00550992	Dutch Childhood Oncology Group\|BFM Germany\|CORS Monza Italy\|Associazione Italiana Ematologia Oncologia Pediatrica\|Australian and New Zealand Children´s Oncology Group\|BFM Austria\|CLCG France Belgium Portugal\|COALL Germany\|CPH, Czech republic\|DFCI consortium USA\|FRALLE France\|Hong Kong\|MD Anderson USA\|NOPHO Scandinavian countries\|PINDA, Chile\|PPLLSG Poland\|Seattle USA\|SJCRH USA\|UKCCSG United Kingdom	Leukemia	January 2006	Not Applicable
NCT00002547	Barbara Ann Karmanos Cancer Institute\|National Cancer Institute (NCI)	Leukemia\|Myelodysplastic Syndromes	August 1987	Phase 2
NCT03657342	Zambon SpA	Bronchiolitis Obliterans\|Chronic Rejection of Lung Transplant\|Lung Transplant Rejection\|Lung Transplant; Complications\|Lung Transplant Failure and Rejection\|Chronic Lung Allograft Dysfunction	April 2, 2019	Phase 3
NCT00253552	OHSU Knight Cancer Institute\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Graft Versus Host Disease\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases\|Sarcoma	May 2004	Not Applicable
NCT04781803	Hospital Universitario Dr. Jose E. Gonzalez	Stem Cell Transplant Complications\|Cytokine Release Syndrome	March 25, 2021	Phase 2
NCT02867800	Monica Bhatia\|Columbia University	Sickle Cell Disease\|Graft Versus Host Disease	July 2016	Phase 1
NCT00298324	European Society for Blood and Marrow Transplantation\|Novartis	Graft vs Host Disease	September 2006	Phase 3
NCT00003187	Virginia Commonwealth University\|National Cancer Institute (NCI)	Leukemia\|Lymphoma\|Myelodysplastic Syndromes	May 1995	Phase 2\|Phase 3
NCT00866684	Charite University, Berlin, Germany	Kidney Transplantation\|Skin Cancer	January 2007	Phase 4
NCT00755040	Vanderbilt-Ingram Cancer Center\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Graft Versus Host Disease\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Neoplasms	October 2008	Phase 3
NCT00827255	Allergan	Dry Eye Disease	January 2009
NCT00154310	Novartis	Renal Transplantation	June 2005	Phase 4
NCT00260689	National Heart, Lung, and Blood Institute (NHLBI)\|National Institutes of Health Clinical Center (CC)	Immunosuppresion\|Thrombocytopenia\|Pancytopenia\|Neutropenia	November 28, 2005	Phase 2
NCT01231854	Technische Universität Dresden	Atopic Dermatitis	November 2010	Phase 4
NCT03250143	Postgraduate Institute of Medical Education and Research	Chronic Refractory Urticaria	December 6, 2016	Phase 1\|Phase 2
NCT01426334	National Cancer Institute (NCI)	Accelerated Phase Chronic Myelogenous Leukemia\|Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Chronic Phase Chronic Myelogenous Leukemia\|Relapsing Chronic Myelogenous Leukemia	September 2011	Phase 1
NCT00840827	Weill Medical College of Cornell University\|Celgene	Myelodysplastic Syndrome	December 2008	Phase 2
NCT02114073	Mashhad University of Medical Sciences	Glaucoma, Open Angle	April 2014	Phase 2
NCT00005937	Neal Young, M.D.\|National Institutes of Health Clinical Center (CC)	Myelodysplastic Syndrome	June 2000	Phase 2
NCT00824811	M.D. Anderson Cancer Center\|Allergan	Epiphora	June 2009	Phase 2
NCT02390674	Newcastle-upon-Tyne Hospitals NHS Trust\|National Institute for Health Research, United Kingdom\|Newcastle University	Myocardial Reperfusion Injury	March 2015	Phase 2
NCT05459649	Peking University People´s Hospital	Immune Thrombocytopenia	July 20, 2022	Phase 2
NCT00020176	National Cancer Institute (NCI)	Breast Cancer	June 2000	Phase 2
NCT00089050	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Leukemia	May 2004	Phase 2
NCT00907036	Cancer Research UK\|National Cancer Institute (NCI)	Lymphoma	July 2009	Phase 2
NCT00436761	Milton S. Hershey Medical Center\|National Cancer Institute (NCI)	Unspecified Childhood Solid Tumor, Protocol Specific	May 2004	Phase 1
NCT00256750	Bristol-Myers Squibb	Kidney Transplantation\|Chronic Kidney Failure	March 2005	Phase 3
NCT00003838	National Heart, Lung, and Blood Institute (NHLBI)\|National Institutes of Health Clinical Center (CC)	Myeloproliferative Disorders\|Acute Myelogenous Leukemia\|Chronic Myelogenous Leukemia\|Myelodysplastic Syndrome\|Acute Lymphoblastic Leukemia	April 15, 1999	Phase 2
NCT01023815	Novartis	de Novo Kidney Transplant Recipients\|Renal Transplantation	April 2009	Phase 3
NCT02274662	Enzyvant Therapeutics GmBH	Poor Thymic Function\|Immunodeficiency\|Athymia\|Immunoreconstitution\|Thymus Transplantation\|Low T Cell Numbers
NCT00081055	Mesoblast International Sàrl\|National Cancer Institute (NCI)\|Mesoblast, Ltd.	Graft Versus Host Disease\|Leukemia\|Myelodysplastic Syndromes		Phase 2
NCT00295425	University Hospital Muenster\|Hoffmann-La Roche	Psoriasis	May 2000	Phase 2
NCT00908180	Cancer Research UK\|National Cancer Institute (NCI)	Lymphoma	July 2009	Phase 2
NCT00005854	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes	December 1999	Phase 2
NCT02701517	Grupo Español de Linfomas y Transplante Autólogo de Médula Ósea	Unrecognized Condition: Mature B or T-cell Neoplasm	September 2003	Phase 2
NCT02865356	Spherium Biomed\|Germans Trias i Pujol Hospital\|Hospital del Mar\|Hospital Sant Joan de Deu\|Hospital Universitario Virgen Macarena\|Hospital Universitario La Fe\|Hospital General Universitario de Alicante\|Fundación de Investigación Biomédica - Hospital Universitario de La Princesa\|Hospital Universitario Virgen de la Victoria\|Hospital Infantil Universitario Niño Jesús, Madrid, Spain	Atopic Dermatitis	September 2016	Phase 2
NCT00154284	Novartis	Organ Transplantation, Renal Transplantation	July 2005	Phase 3
NCT01300572	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Chronic Myelomonocytic Leukemia\|Previously Treated Myelodysplastic Syndrome\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Refractory Anemia With Excess Blasts\|Secondary Acute Myeloid Leukemia	January 2012	Phase 1
NCT01504906	AstraZeneca	Healthy	January 2012	Phase 1
NCT00820911	Novartis Pharmaceuticals\|Novartis	Kidney Transplantation	September 2008	Phase 2
NCT04988256	University of Southern California	DRESS Syndrome\|Drug-Induced Hypersensitivity Syndrome	September 27, 2021	Early Phase 1
NCT00290628	Masonic Cancer Center, University of Minnesota\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Diamond-blackfan Anemia\|Fanconi Anemia\|Graft Versus Host Disease\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases	October 1999	Not Applicable
NCT00542152	Groupe d´Etude Therapeutique des Affections Inflammatoires Digestives	Ulcerative Colitis\|Steroid Refractory	June 2007	Phase 4
NCT00006451	Masonic Cancer Center, University of Minnesota	Graft Versus Host Disease\|Leukemia\|Lymphoma	April 1996	Phase 3
NCT02435901	Northwell Health	Sickle Cell Disease\|Beta Thalassemia-Major	December 2008	Phase 1\|Phase 2
NCT02144025	Hospital Universitario Dr. Jose E. Gonzalez	Graft-Versus-Host Disease	May 2014	Phase 2
NCT01276457	Novartis Pharmaceuticals\|Novartis	Transplantation Infection	May 2006	Phase 3
NCT02478424	Rabin Medical Center	Graft vs Host Disease	July 2015	Phase 2
NCT01193283	National Heart, Lung, and Blood Institute (NHLBI)\|National Institutes of Health Clinical Center (CC)	Aplastic Anemia\|Neutropenia\|Pancytopenia\|Severe Aplastic Anemia	August 2010	Phase 1\|Phase 2
NCT01788501	Seoul National University Hospital	Graft vs Host Disease	November 2011	Phase 2\|Phase 3
NCT00547196	City of Hope Medical Center\|National Cancer Institute (NCI)	Leukemia\|Lymphoma\|Myelodysplastic Syndromes	August 16, 2005	Not Applicable
NCT00045305	Eastern Cooperative Oncology Group\|National Cancer Institute (NCI)	Leukemia\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Neoplasms	May 2005	Phase 2
NCT00334672	Children´s Cancer and Leukaemia Group\|National Cancer Institute (NCI)	Nonneoplastic Condition	March 2006	Phase 3
NCT00328653	Santen SAS	Conjunctivitis, Vernal	May 2006	Phase 2\|Phase 3
NCT00006054	Fairview University Medical Center\|Office of Rare Diseases (ORD)	Immunologic Deficiency Syndromes\|Chediak-Higashi Syndrome\|Common Variable Immunodeficiency\|Graft Versus Host Disease\|X-Linked Lymphoproliferative Syndrome\|Familial Erythrophagocytic Lymphohistiocytosis\|Hemophagocytic Lymphohistiocytosis\|X-linked Agammaglobulinemia\|Wiskott-Aldrich Syndrome\|Chronic Granulomatous Disease\|X-linked Hyper IgM Syndrome\|Severe Combined Immunodeficiency\|Leukocyte Adhesion Deficiency Syndrome\|Virus-Associated Hemophagocytic Syndrome	March 2000	Not Applicable
NCT04542252	SymBio Pharmaceuticals	Drug Drug Interaction	November 9, 2020	Phase 1
NCT00553202	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	January 2008	Phase 2
NCT00003196	Fred Hutchinson Cancer Center\|National Heart, Lung, and Blood Institute (NHLBI)\|National Cancer Institute (NCI)	Adult Nasal Type Extranodal NK+T-cell Lymphoma\|Anaplastic Large Cell Lymphoma\|Angioimmunoblastic T-cell Lymphoma\|Cutaneous B-cell Non-Hodgkin Lymphoma\|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue\|Hepatosplenic T-cell Lymphoma\|Intraocular Lymphoma\|Nodal Marginal Zone B-cell Lymphoma\|Noncutaneous Extranodal Lymphoma\|Peripheral T-cell Lymphoma\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Burkitt Lymphoma\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent Adult Diffuse Mixed Cell Lymphoma\|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma\|Recurrent Adult Grade III Lymphomatoid Granulomatosis\|Recurrent Adult Immunoblastic Large Cell Lymphoma\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Adult T-cell Leukemia+Lymphoma\|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Grade 3 Follicular Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Mycosis Fungoides+Sezary Syndrome\|Recurrent Small Lymphocytic Lymphoma\|Refractory Chronic Lymphocytic Leukemia\|Refractory Hairy Cell Leukemia\|Refractory Multiple Myeloma\|Small Intestine Lymphoma\|Splenic Marginal Zone Lymphoma\|Stage II Multiple Myeloma\|Stage III Multiple Myeloma\|Testicular Lymphoma\|Waldenström Macroglobulinemia	September 1997	Not Applicable
NCT01497483	University of California, San Francisco\|National Institute of General Medical Sciences (NIGMS)	Healthy	December 2011	Phase 1
NCT00408187	Aurinia Pharmaceuticals Inc.	Psoriasis	December 2006	Phase 3
NCT00428064	Wyeth is now a wholly owned subsidiary of Pfizer	Renal Transplantation	May 1998	Phase 3
NCT00775632	University Health Network, Toronto\|Bayer	Graft Versus Host Disease\|Bone Marrow Transplantation	October 2008	Phase 2
NCT00507793	Wyeth is now a wholly owned subsidiary of Pfizer	Kidney Transplantation	April 2000	Phase 4
NCT01080586	Panacea Biotec Ltd	Healthy Volunteers	September 2007	Not Applicable
NCT02181478	Case Comprehensive Cancer Center\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Acute Myelogenous Leukemia\|Myelodysplastic Syndromes\|Myelofibrosis\|Relapsed Non-Hodgkin Lymphoma\|Refractory Non-Hodgkin Lymphoma\|Hodgkin Lymphoma\|Refractory Hodgkin Lymphoma\|Relapsed Chronic Lymphocytic Leukemia\|Refractory Chronic Lymphocytic Leukemia\|Lymphoid Malignancies\|Chronic Myelogenous Leukemia	July 22, 2015	Early Phase 1
NCT00014235	Fred Hutchinson Cancer Center\|National Heart, Lung, and Blood Institute (NHLBI)\|National Cancer Institute (NCI)	Acute Myeloid Leukemia+Transient Myeloproliferative Disorder\|Acute Undifferentiated Leukemia\|Adult Acute Lymphoblastic Leukemia in Remission\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Adult Nasal Type Extranodal NK+T-cell Lymphoma\|Anaplastic Large Cell Lymphoma\|Angioimmunoblastic T-cell Lymphoma\|Blastic Plasmacytoid Dendritic Cell Neoplasm\|Childhood Acute Lymphoblastic Leukemia in Remission\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Burkitt Lymphoma\|Childhood Diffuse Large Cell Lymphoma\|Childhood Immunoblastic Large Cell Lymphoma\|Childhood Myelodysplastic Syndromes\|Childhood Nasal Type Extranodal NK+T-cell Lymphoma\|Chronic Myelomonocytic Leukemia\|Cutaneous B-cell Non-Hodgkin Lymphoma\|de Novo Myelodysplastic Syndromes\|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue\|Hepatosplenic T-cell Lymphoma\|Intraocular Lymphoma\|Juvenile Myelomonocytic Leukemia\|Mast Cell Leukemia\|Myelodysplastic+Myeloproliferative Neoplasm, Unclassifiable\|Nodal Marginal Zone B-cell Lymphoma\|Noncutaneous Extranodal Lymphoma\|Peripheral T-cell Lymphoma\|Post-transplant Lymphoproliferative Disorder\|Previously Treated Myelodysplastic Syndromes\|Primary Systemic Amyloidosis\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Adult Burkitt Lymphoma\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent Adult Diffuse Mixed Cell Lymphoma\|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma\|Recurrent Adult Grade III Lymphomatoid Granulomatosis\|Recurrent Adult Hodgkin Lymphoma\|Recurrent Adult Immunoblastic Large Cell Lymphoma\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Adult T-cell Leukemia+Lymphoma\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Recurrent Childhood Anaplastic Large Cell Lymphoma\|Recurrent Childhood Grade III Lymphomatoid Granulomatosis\|Recurrent Childhood Large Cell Lymphoma\|Recurrent Childhood Lymphoblastic Lymphoma\|Recurrent Childhood Small Noncleaved Cell Lymphoma\|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Grade 3 Follicular Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Mycosis Fungoides+Sezary Syndrome\|Recurrent Small Lymphocytic Lymphoma\|Recurrent+Refractory Childhood Hodgkin Lymphoma\|Refractory Chronic Lymphocytic Leukemia\|Refractory Hairy Cell Leukemia\|Refractory Multiple Myeloma\|Small Intestine Lymphoma\|Splenic Marginal Zone Lymphoma\|Stage II Multiple Myeloma\|Stage III Multiple Myeloma\|T-cell Large Granular Lymphocyte Leukemia\|Testicular Lymphoma\|Untreated Adult Acute Lymphoblastic Leukemia\|Untreated Adult Acute Myeloid Leukemia\|Untreated Childhood Acute Lymphoblastic Leukemia\|Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies\|Waldenström Macroglobulinemia	December 2000	Not Applicable
NCT00003270	Roswell Park Cancer Institute	Graft Versus Host Disease\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes	September 4, 1997	Phase 2
NCT01968057	Eli Lilly and Company	Healthy Volunteers	October 2013	Phase 1
NCT01220531	Enzyvant Therapeutics GmBH\|National Institutes of Health (NIH)\|National Institute of Allergy and Infectious Diseases (NIAID)\|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	Complete DiGeorge Anomaly\|DiGeorge Syndrome\|DiGeorge Anomaly\|Complete DiGeorge Syndrome
NCT00040846	Fred Hutchinson Cancer Center\|National Heart, Lung, and Blood Institute (NHLBI)\|National Cancer Institute (NCI)	Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Adult Nasal Type Extranodal NK+T-cell Lymphoma\|Anaplastic Large Cell Lymphoma\|Angioimmunoblastic T-cell Lymphoma\|Childhood Burkitt Lymphoma\|Childhood Chronic Myelogenous Leukemia\|Childhood Diffuse Large Cell Lymphoma\|Childhood Immunoblastic Large Cell Lymphoma\|Childhood Nasal Type Extranodal NK+T-cell Lymphoma\|Chronic Phase Chronic Myelogenous Leukemia\|Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma\|Contiguous Stage II Grade 1 Follicular Lymphoma\|Contiguous Stage II Grade 2 Follicular Lymphoma\|Contiguous Stage II Marginal Zone Lymphoma\|Contiguous Stage II Small Lymphocytic Lymphoma\|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue\|Hepatosplenic T-cell Lymphoma\|Myelodysplastic+Myeloproliferative Neoplasm, Unclassifiable\|Nodal Marginal Zone B-cell Lymphoma\|Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma\|Noncontiguous Stage II Grade 1 Follicular Lymphoma\|Noncontiguous Stage II Grade 2 Follicular Lymphoma\|Noncontiguous Stage II Marginal Zone Lymphoma\|Noncontiguous Stage II Small Lymphocytic Lymphoma\|Peripheral T-cell Lymphoma\|Previously Treated Myelodysplastic Syndromes\|Progressive Hairy Cell Leukemia, Initial Treatment\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Adult Burkitt Lymphoma\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent Adult Diffuse Mixed Cell Lymphoma\|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma\|Recurrent Adult Grade III Lymphomatoid Granulomatosis\|Recurrent Adult Hodgkin Lymphoma\|Recurrent Adult Immunoblastic Large Cell Lymphoma\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Adult T-cell Leukemia+Lymphoma\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Recurrent Childhood Anaplastic Large Cell Lymphoma\|Recurrent Childhood Large Cell Lymphoma\|Recurrent Childhood Lymphoblastic Lymphoma\|Recurrent Childhood Small Noncleaved Cell Lymphoma\|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Grade 3 Follicular Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Mycosis Fungoides+Sezary Syndrome\|Recurrent Small Lymphocytic Lymphoma\|Recurrent+Refractory Childhood Hodgkin Lymphoma\|Refractory Chronic Lymphocytic Leukemia\|Refractory Hairy Cell Leukemia\|Refractory Multiple Myeloma\|Relapsing Chronic Myelogenous Leukemia\|Splenic Marginal Zone Lymphoma\|Stage I Adult Diffuse Small Cleaved Cell Lymphoma\|Stage I Childhood Anaplastic Large Cell Lymphoma\|Stage I Childhood Large Cell Lymphoma\|Stage I Cutaneous T-cell Non-Hodgkin Lymphoma\|Stage I Grade 1 Follicular Lymphoma\|Stage I Grade 2 Follicular Lymphoma\|Stage I Mantle Cell Lymphoma\|Stage I Marginal Zone Lymphoma\|Stage I Mycosis Fungoides+Sezary Syndrome\|Stage I Small Lymphocytic Lymphoma\|Stage II Childhood Anaplastic Large Cell Lymphoma\|Stage II Childhood Large Cell Lymphoma\|Stage II Cutaneous T-cell Non-Hodgkin Lymphoma\|Stage II Mycosis Fungoides+Sezary Syndrome\|Stage III Adult Diffuse Large Cell Lymphoma\|Stage III Adult Diffuse Small Cleaved Cell Lymphoma\|Stage III Childhood Anaplastic Large Cell Lymphoma\|Stage III Childhood Large Cell Lymphoma\|Stage III Cutaneous T-cell Non-Hodgkin Lymphoma\|Stage III Grade 1 Follicular Lymphoma\|Stage III Grade 2 Follicular Lymphoma\|Stage III Mantle Cell Lymphoma\|Stage III Marginal Zone Lymphoma\|Stage III Mycosis Fungoides+Sezary Syndrome\|Stage III Small Lymphocytic Lymphoma\|Stage IV Adult Diffuse Large Cell Lymphoma\|Stage IV Adult Diffuse Small Cleaved Cell Lymphoma\|Stage IV Childhood Anaplastic Large Cell Lymphoma\|Stage IV Childhood Large Cell Lymphoma\|Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma\|Stage IV Grade 1 Follicular Lymphoma\|Stage IV Grade 2 Follicular Lymphoma\|Stage IV Mantle Cell Lymphoma\|Stage IV Marginal Zone Lymphoma\|Stage IV Mycosis Fungoides+Sezary Syndrome\|Stage IV Small Lymphocytic Lymphoma\|T-cell Large Granular Lymphocyte Leukemia\|Waldenström Macroglobulinemia	November 2001	Phase 2
NCT00544115	City of Hope Medical Center\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Graft Versus Host Disease\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases\|Precancerous+Nonmalignant Condition	October 16, 2001	Phase 2
NCT00074269	University of California, San Diego\|National Cancer Institute (NCI)	Breast Cancer	July 2003	Phase 2
NCT00369382	Wyeth is now a wholly owned subsidiary of Pfizer	Graft Rejection\|Kidney Failure	September 2006	Phase 4
NCT00005941	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Cervical Cancer\|Vaginal Cancer	November 1999	Phase 2
NCT00041288	University of Texas Southwestern Medical Center	Leukemia\|Lymphoma	October 2001	Phase 2
NCT00070187	Children´s Oncology Group\|National Cancer Institute (NCI)	Lymphoma	November 2003	Phase 2\|Phase 3
NCT00017654	Northwestern Memorial Hospital\|Office of Rare Diseases (ORD)	Graft Versus Host Disease\|Aplastic Anemia	April 2001	Not Applicable
NCT00773292	Imperial College London\|Medical Research Council\|University Hospital Birmingham\|Imperial College Healthcare NHS Trust	HTLV I Associated Myelopathy	August 2006	Phase 2\|Phase 3
NCT04107675	Zambon SpA	Bronchiolitis Obliterans\|GVHD, Chronic\|Stem Cell Transplant Complications	February 11, 2020	Phase 2
NCT01109056	Allergan	Pterygium	June 2010	Phase 2
NCT00972660	Guangdong Provincial People´s Hospital\|Sun Yat-sen University	Graft Versus Host Disease	September 2009	Phase 2
NCT00002790	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Graft Versus Host Disease\|Leukemia\|Myelodysplastic Syndromes	March 1996	Phase 1\|Phase 2
NCT00171717	Novartis	Maintenance Liver Transplant Patients With New Onset Diabetes	February 2004	Phase 4
NCT00027443	Mayo Clinic\|FDA Office of Orphan Products Development	Myocarditis	August 2001	Not Applicable
NCT00502073	Sirion Therapeutics, Inc.	Dry Eye Syndromes		Phase 3
NCT00054340	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Graft Versus Host Disease\|Leukemia\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases	October 2002	Phase 1\|Phase 2
NCT00003335	Case Comprehensive Cancer Center\|National Cancer Institute (NCI)	Graft Versus Host Disease\|Leukemia\|Lymphoma\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases	January 1998	Phase 2
NCT00001533	National Heart, Lung, and Blood Institute (NHLBI)\|National Institutes of Health Clinical Center (CC)	Anemia\|Leukemia, T-Cell\|Lymphocytosis\|Neutropenia\|Thrombocytopenia	September 1996	Phase 1
NCT00383396	Innovative Medical	Pterygia		Phase 4
NCT00619645	University of California, Davis	Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes	June 2007	Phase 2
NCT02630563	Hoffmann-La Roche	Pediatric Liver Transplantation	May 2003	Phase 2
NCT01062555	University of Minnesota\|Roche Pharma AG\|Wyeth is now a wholly owned subsidiary of Pfizer\|Genzyme, a Sanofi Company	CNI Side Effects	October 1, 2006	Phase 1\|Phase 2
NCT01762657	Perle Bioscience, Inc.	Type 1 Diabetes	September 2014	Phase 3
NCT00213590	University Hospital, Rouen	Kidney Transplantation\|Primary Prevention\|Kidney Failure	April 2000	Phase 3
NCT03231592	Community Health Center of Franklin County\|Just Roots\|Massachusetts General Hospital	Overweight and Obesity\|Nutrition Poor\|Diet Modification	May 10, 2017	Not Applicable
NCT01287078	National Heart, Lung, and Blood Institute (NHLBI)\|National Institutes of Health Clinical Center (CC)	Constrictive Bronchiolitis\|Bronchiolitis Obliterans\|Graft vs Host Disease\|Bronchiolitis, Exudative\|Bronchiolitis, Proliferative	January 29, 2011	Phase 2
NCT01690520	Nohla Therapeutics, Inc.\|National Cancer Institute (NCI)\|National Heart, Lung, and Blood Institute (NHLBI)	Acute Biphenotypic Leukemia\|Acute Lymphoblastic Leukemia in Remission\|Acute Myeloid Leukemia in Remission\|Chronic Myelogenous Leukemia\|Myelodysplastic Syndrome	December 11, 2012	Phase 2
NCT00029380	National Heart, Lung, and Blood Institute (NHLBI)	Hematologic Diseases\|Anemia, Sickle Cell\|Beta-Thalassemia\|Hematopoietic Stem Cell Transplantation	January 1999	Phase 2
NCT05588869	Sohag University	Steroid Dependent and Frequent Relapsing Nephrotic Syndrome	October 20, 2022
NCT00453388	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)\|National Heart, Lung, and Blood Institute (NHLBI)	Acute Myeloid Leukemia in Remission\|de Novo Myelodysplastic Syndrome\|Fanconi Anemia\|Previously Treated Myelodysplastic Syndrome	February 2007	Phase 2
NCT01699360	Central South University	Kidney Transplantation	September 2012	Phase 4
NCT00027820	Fred Hutchinson Cancer Center\|National Heart, Lung, and Blood Institute (NHLBI)\|National Cancer Institute (NCI)	Adult Acute Myeloid Leukemia in Remission\|Childhood Acute Lymphoblastic Leukemia in Remission\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Myelodysplastic Syndrome\|Childhood Renal Cell Carcinoma\|Chronic Myelomonocytic Leukemia\|Clear Cell Renal Cell Carcinoma\|de Novo Myelodysplastic Syndrome\|Metastatic Renal Cell Cancer\|Previously Treated Myelodysplastic Syndrome\|Progression of Multiple Myeloma or Plasma Cell Leukemia\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Adult Hodgkin Lymphoma\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Adult Non-Hodgkin Lymphoma\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Recurrent Childhood Lymphoblastic Lymphoma\|Recurrent Childhood Non-Hodgkin Lymphoma\|Refractory Anemia\|Refractory Anemia With Ringed Sideroblasts\|Refractory Childhood Hodgkin Lymphoma\|Refractory Chronic Lymphocytic Leukemia\|Renal Medullary Carcinoma\|Type 1 Papillary Renal Cell Carcinoma\|Type 2 Papillary Renal Cell Carcinoma\|Untreated Adult Acute Lymphoblastic Leukemia\|Untreated Adult Acute Myeloid Leukemia\|Untreated Childhood Acute Lymphoblastic Leukemia	August 2001	Phase 1\|Phase 2
NCT03466567	Novo Nordisk A+S	Diabetes\|Diabetes Mellitus, Type 2	March 15, 2018	Phase 1
NCT00281879	OHSU Knight Cancer Institute\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Neoplasms\|Unusual Cancers of Childhood	February 2006	Phase 2
NCT01810926	Franco Locatelli\|University of Milano Bicocca\|medac GmbH\|Fresenius AG\|Bambino Gesù Hospital and Research Institute	Graft Versus Host Disease	September 2011	Phase 2
NCT01266148	Novartis Pharmaceuticals\|Novartis	Renal Function and Chronic Allograft Vasculopathy	November 2009	Phase 4
NCT00322101	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)\|National Heart, Lung, and Blood Institute (NHLBI)	Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome\|Acute Myeloid Leukemia+Transient Myeloproliferative Disorder\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Myelodysplastic Syndromes\|de Novo Myelodysplastic Syndromes\|Myelodysplastic Syndrome With Isolated Del(5q)\|Myelodysplastic+Myeloproliferative Neoplasm, Unclassifiable\|Previously Treated Myelodysplastic Syndromes\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Secondary Acute Myeloid Leukemia\|Secondary Myelodysplastic Syndromes	January 2006	Phase 3
NCT00005852	H. Lee Moffitt Cancer Center and Research Institute\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Graft Versus Host Disease\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes	June 1996	Phase 2
NCT00919815	London School of Hygiene and Tropical Medicine\|Homes and Hospitals of St Giles\|Alert Hospital, Ethiopia\|Armauer Hansen Research Institute, Ethiopia	Leprosy	August 2010	Phase 2\|Phase 3
NCT00010361	Fred Hutchinson Cancer Center\|Office of Rare Diseases (ORD)	Metabolism, Inborn Errors\|Granulomatous Disease, Chronic	November 2000	Not Applicable
NCT00186628	Stanford University\|The Leukemia and Lymphoma Society\|National Cancer Institute (NCI)	Leukemia, Mast-Cell\|Mantle-cell Lymphoma	June 2005	Phase 2
NCT03602898	Fred Hutchinson Cancer Center	Acute Lymphoblastic Leukemia in Remission\|Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome\|Chronic Myelomonocytic Leukemia\|Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Hematopoietic and Lymphoid System Neoplasm\|Myelodysplastic Syndrome\|Myelofibrosis\|Myeloproliferative Neoplasm\|Recurrent Acute Myeloid Leukemia\|Recurrent Hodgkin Lymphoma\|Recurrent Non-Hodgkin Lymphoma\|Refractory Acute Myeloid Leukemia\|Therapy-Related Acute Myeloid Leukemia	June 1, 2021	Phase 2
NCT03689465	Nanfang Hospital of Southern Medical University	Hematopoietic Stem Cell Transplantation	October 29, 2018	Phase 4
NCT02229955	Hanlim Pharm. Co., Ltd.	Dry Eye Syndromes	December 2013	Phase 3
NCT05109390	Alexion Pharmaceuticals\|Achillion, a wholly owned subsidiary of Alexion	Healthy	July 27, 2018	Phase 1
NCT04492891	Bryan Burt, MD\|Brigham and Women´s Hospital\|Baylor College of Medicine	SARS (Disease)	November 23, 2020	Phase 2
NCT00387959	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Leukemia\|Lymphoma	July 2006	Phase 2
NCT05112263	Postgraduate Institute of Medical Education and Research\|All India Institute of Medical Sciences, New Delhi	Ulcerative Colitis	January 1, 2023	Not Applicable
NCT04375631	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Recurrent Acute Myeloid Leukemia\|Recurrent Chronic Myelomonocytic Leukemia\|Recurrent Myelodysplastic Syndrome\|Refractory Acute Myeloid Leukemia\|Refractory Chronic Myelomonocytic Leukemia\|Refractory Mixed Phenotype Acute Leukemia\|Refractory Myelodysplastic Syndrome\|Refractory Acute Leukemia of Ambiguous Lineage\|Refractory Acute Undifferentiated Leukemia	December 3, 2020	Phase 1
NCT00005799	Fred Hutchinson Cancer Center\|National Heart, Lung, and Blood Institute (NHLBI)\|National Cancer Institute (NCI)	Accelerated Phase Chronic Myelogenous Leukemia\|Adult Acute Lymphoblastic Leukemia in Remission\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|B-cell Chronic Lymphocytic Leukemia\|Childhood Acute Lymphoblastic Leukemia in Remission\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Chronic Myelogenous Leukemia\|Childhood Myelodysplastic Syndromes\|Childhood Renal Cell Carcinoma\|Chronic Phase Chronic Myelogenous Leukemia\|Clear Cell Renal Cell Carcinoma\|de Novo Myelodysplastic Syndromes\|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue\|Nodal Marginal Zone B-cell Lymphoma\|Previously Treated Myelodysplastic Syndromes\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma\|Recurrent Adult Hodgkin Lymphoma\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Mycosis Fungoides+Sezary Syndrome\|Recurrent Small Lymphocytic Lymphoma\|Recurrent+Refractory Childhood Hodgkin Lymphoma\|Refractory Chronic Lymphocytic Leukemia\|Refractory Hairy Cell Leukemia\|Refractory Multiple Myeloma\|Relapsing Chronic Myelogenous Leukemia\|Splenic Marginal Zone Lymphoma\|Stage III Renal Cell Cancer\|Stage IV Renal Cell Cancer\|T-cell Large Granular Lymphocyte Leukemia\|Type 1 Papillary Renal Cell Carcinoma\|Type 2 Papillary Renal Cell Carcinoma\|Waldenström Macroglobulinemia	November 1999	Not Applicable
NCT05294666	Peking University Third Hospital	Graft Versus Host Disease in Eye	April 1, 2020	Phase 4
NCT02653196	Montefiore Medical Center\|Children´s Hospital Los Angeles\|Nationwide Children´s Hospital	Neuroepithelial Tumor\|Solid Tumor\|Allogeneic Hematopoietic Stem Cell Transplantation	September 2015	Early Phase 1
NCT00060424	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	B-Cell Prolymphocytic Leukemia\|Chronic Lymphocytic Leukemia\|Prolymphocytic Leukemia\|Recurrent Chronic Lymphocytic Leukemia\|Recurrent Small Lymphocytic Lymphoma\|Refractory Chronic Lymphocytic Leukemia\|T-Cell Prolymphocytic Leukemia	March 2003	Phase 2
NCT00043979	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Sarcoma	September 19, 2002	Phase 2
NCT00167947	Wyeth is now a wholly owned subsidiary of Pfizer	Kidney Failure\|Graft vs Host Disease	January 2005	Phase 3
NCT01109498	Amsterdam Molecular Therapeutics\|International Antiviral Therapy Evaluation Center	Familial Lipoprotein Lipase Deficiency	August 2007	Phase 2\|Phase 3
NCT00110058	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Leukemia	February 2005	Phase 2
NCT01028092	University Hospital, Brest\|Novartis\|Roche Pharma AG\|Genzyme, a Sanofi Company\|Ministry of Health, France	Renal Transplant	March 2009	Phase 3
NCT01758107	Chulalongkorn University	Renal Transplant	August 2010	Phase 4
NCT00000524	University of Utah\|National Heart, Lung, and Blood Institute (NHLBI)	Cardiovascular Diseases\|Heart Diseases\|Myocarditis	July 1986	Phase 2
NCT00102583	National Eye Institute (NEI)\|National Institutes of Health Clinical Center (CC)	Graft Vs Host Disease	October 14, 2004	Phase 1
NCT04376970	Military Hospital of Tunis	Adenoviral Keratoconjunctivitis	April 1, 2017	Phase 4
NCT00004485	Fred Hutchinson Cancer Center\|Office of Rare Diseases (ORD)	Sickle Cell Anemia	December 1999	Phase 1\|Phase 2
NCT00916045	King´s College Hospital NHS Trust	Leukemia, Myeloid, Acute\|Myelodysplastic Syndromes\|Leukemia, Lymphoblastic, Acute\|Lymphoma, Non-Hodgkin\|Hodgkin Disease\|Chronic Lymphocytic Leukemia	September 2009	Phase 2
NCT01177371	Case Comprehensive Cancer Center	Accelerated Phase Chronic Myelogenous Leukemia\|Adult Acute Lymphoblastic Leukemia in Remission\|Adult Acute Megakaryoblastic Leukemia (M7)\|Adult Acute Monoblastic Leukemia (M5a)\|Adult Acute Monocytic Leukemia (M5b)\|Adult Acute Myeloblastic Leukemia With Maturation (M2)\|Adult Acute Myeloblastic Leukemia Without Maturation (M1)\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With T(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With T(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With T(8;21)(q22;q22)\|Adult Acute Myelomonocytic Leukemia (M4)\|Adult Acute Promyelocytic Leukemia (M3)\|Adult Erythroleukemia (M6a)\|Adult Nasal Type Extranodal NK+T-cell Lymphoma\|Adult Pure Erythroid Leukemia (M6b)\|Anaplastic Large Cell Lymphoma\|Angioimmunoblastic T-cell Lymphoma\|Burkitt Lymphoma\|Childhood Acute Erythroleukemia (M6)\|Childhood Acute Lymphoblastic Leukemia in Remission\|Childhood Acute Megakaryocytic Leukemia (M7)\|Childhood Acute Monoblastic Leukemia (M5a)\|Childhood Acute Monocytic Leukemia (M5b)\|Childhood Acute Myeloblastic Leukemia With Maturation (M2)\|Childhood Acute Myeloblastic Leukemia Without Maturation (M1)\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Acute Myelomonocytic Leukemia (M4)\|Childhood Acute Promyelocytic Leukemia (M3)\|Childhood Chronic Myelogenous Leukemia\|Childhood Myelodysplastic Syndromes\|Chronic Phase Chronic Myelogenous Leukemia\|Cutaneous B-cell Non-Hodgkin Lymphoma\|De Novo Myelodysplastic Syndromes\|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue\|Hepatosplenic T-cell Lymphoma\|Intraocular Lymphoma\|Nodal Marginal Zone B-cell Lymphoma\|Peripheral T-Cell Lymphoma\|Post-transplant Lymphoproliferative Disorder\|Previously Treated Myelodysplastic Syndromes\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Adult Burkitt Lymphoma\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent Adult Diffuse Mixed Cell Lymphoma\|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma\|Recurrent Adult Grade III Lymphomatoid Granulomatosis\|Recurrent Adult Hodgkin Lymphoma\|Recurrent Adult Immunoblastic Large Cell Lymphoma\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Adult Non-Hodgkin Lymphoma\|Recurrent Adult T-cell Leukemia+Lymphoma\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Grade 3 Follicular Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Mycosis Fungoides+Sezary Syndrome\|Recurrent Small Lymphocytic Lymphoma\|Refractory Multiple Myeloma\|Relapsing Chronic Myelogenous Leukemia\|Secondary Myelodysplastic Syndromes\|Small Intestine Lymphoma\|Splenic Marginal Zone Lymphoma\|Testicular Lymphoma\|Waldenstrom Macroglobulinemia	March 1988	Phase 2
NCT04812951	Campus Bio-Medico University	Ocular Surface Disease\|Ocular Inflammation	February 17, 2021	Early Phase 1
NCT00023244	National Institute of Allergy and Infectious Diseases (NIAID)\|Cooperative Clinical Trials in Pediatric Transplantation	End-Stage Renal Disease	January 2001	Phase 2
NCT01319773	Allergan	Dry Eye Syndromes	November 2010	Phase 1
NCT00104858	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Chronic Lymphocytic Leukemia\|Prolymphocytic Leukemia\|Recurrent Small Lymphocytic Lymphoma\|Refractory Chronic Lymphocytic Leukemia\|Stage III Chronic Lymphocytic Leukemia\|Stage III Small Lymphocytic Lymphoma\|Stage IV Chronic Lymphocytic Leukemia\|Stage IV Small Lymphocytic Lymphoma\|T-Cell Large Granular Lymphocyte Leukemia	December 2004	Phase 2
NCT05353101	Second Affiliated Hospital of Nanchang University	Vernal Keratoconjunctivitis\|Cyclosporine 0.05% Eye Drops	July 1, 2020	Phase 1
NCT01064830	University of North Carolina, Chapel Hill\|Allergan	Brittle Nail Syndrome	February 2010	Phase 2
NCT00006251	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Acute Undifferentiated Leukemia\|Adult Nasal Type Extranodal NK+T-cell Lymphoma\|Anaplastic Large Cell Lymphoma\|Angioimmunoblastic T-cell Lymphoma\|Childhood Burkitt Lymphoma\|Childhood Diffuse Large Cell Lymphoma\|Childhood Grade III Lymphomatoid Granulomatosis\|Childhood Immunoblastic Large Cell Lymphoma\|Childhood Myelodysplastic Syndromes\|Childhood Nasal Type Extranodal NK+T-cell Lymphoma\|Chronic Myelomonocytic Leukemia\|Cutaneous B-cell Non-Hodgkin Lymphoma\|de Novo Myelodysplastic Syndromes\|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue\|Hepatosplenic T-cell Lymphoma\|Intraocular Lymphoma\|Juvenile Myelomonocytic Leukemia\|Mast Cell Leukemia\|Myelodysplastic+Myeloproliferative Neoplasm, Unclassifiable\|Myeloid+NK-cell Acute Leukemia\|Nodal Marginal Zone B-cell Lymphoma\|Noncutaneous Extranodal Lymphoma\|Peripheral T-cell Lymphoma\|Post-transplant Lymphoproliferative Disorder\|Previously Treated Myelodysplastic Syndromes\|Primary Systemic Amyloidosis\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Adult Burkitt Lymphoma\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent Adult Diffuse Mixed Cell Lymphoma\|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma\|Recurrent Adult Grade III Lymphomatoid Granulomatosis\|Recurrent Adult Hodgkin Lymphoma\|Recurrent Adult Immunoblastic Large Cell Lymphoma\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Adult T-cell Leukemia+Lymphoma\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Recurrent Childhood Anaplastic Large Cell Lymphoma\|Recurrent Childhood Grade III Lymphomatoid Granulomatosis\|Recurrent Childhood Large Cell Lymphoma\|Recurrent Childhood Lymphoblastic Lymphoma\|Recurrent Childhood Small Noncleaved Cell Lymphoma\|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Grade 3 Follicular Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Mycosis Fungoides+Sezary Syndrome\|Recurrent Renal Cell Cancer\|Recurrent Small Lymphocytic Lymphoma\|Recurrent+Refractory Childhood Hodgkin Lymphoma\|Refractory Chronic Lymphocytic Leukemia\|Refractory Hairy Cell Leukemia\|Refractory Multiple Myeloma\|Small Intestine Lymphoma\|Splenic Marginal Zone Lymphoma\|Stage II Multiple Myeloma\|Stage III Multiple Myeloma\|T-cell Large Granular Lymphocyte Leukemia\|Testicular Lymphoma\|Waldenström Macroglobulinemia	May 2000	Phase 1\|Phase 2
NCT01527045	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)\|National Heart, Lung, and Blood Institute (NHLBI)	Aggressive Non-Hodgkin Lymphoma\|Blasts Under 5 Percent of Bone Marrow Nucleated Cells\|Chronic Lymphocytic Leukemia\|Loss of Chromosome 17p\|Myelodysplastic+Myeloproliferative Neoplasm\|Non-Hodgkin Lymphoma\|Prolymphocytic Leukemia\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Aggressive Adult Non-Hodgkin Lymphoma\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Recurrent Chronic Lymphocytic Leukemia\|Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Recurrent Diffuse Large B-Cell Lymphoma\|Recurrent Hodgkin Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Non-Hodgkin Lymphoma\|Recurrent Plasma Cell Myeloma\|Recurrent Small Lymphocytic Lymphoma\|Waldenstrom Macroglobulinemia	September 25, 2012	Phase 2
NCT00008203	Herbert Irving Comprehensive Cancer Center\|National Cancer Institute (NCI)	Breast Cancer	May 1996	Phase 3
NCT01334892	Pari Pharma GmbH	Bronchiolitis Obliterans	December 2009	Phase 2\|Phase 3
NCT00003060	Louisiana State University Health Sciences Center Shreveport	Melanoma (Skin)	March 1995	Phase 1
NCT00031980	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Anemia\|Leukemia\|Neutropenia\|Thrombocytopenia	March 2002	Phase 2
NCT02845596	Michael Pulsipher, MD\|Children´s Hospital Los Angeles	Severe Aplastic Anemia	August 2016	Not Applicable
NCT02462252	BioLineRx, Ltd.	Aplastic Anemia\|Hypoplastic Myelodysplastic Syndrome	October 2015	Phase 2
NCT00022737	National Cancer Institute (NCI)	Childhood Acute Lymphoblastic Leukemia in Remission\|Recurrent Childhood Acute Lymphoblastic Leukemia	October 2002	Phase 3
NCT04878770	Erasmus Medical Center\|ZonMw: The Netherlands Organisation for Health Research and Development	Dermatitis, Atopic	August 16, 2021	Not Applicable
NCT00050648	Rockefeller University\|Facet Biotech	Psoriasis	October 1997	Phase 1\|Phase 2
NCT01268995	Medical University of Vienna	New Onset Diabetes Mellitus After Renal Transplantation	September 2009	Phase 2
NCT00001964	National Heart, Lung, and Blood Institute (NHLBI)\|National Institutes of Health Clinical Center (CC)	Severe Aplastic Anemia	March 17, 2000	Phase 2
NCT04532918	AstraZeneca\|Parexel	Chronic Kidney Disease	September 10, 2020	Phase 1
NCT00056095	UNICANCER	Kidney Cancer	November 4, 2002	Phase 2
NCT00119366	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Childhood Myelodysplastic Syndromes\|Chronic Myelomonocytic Leukemia\|Previously Treated Myelodysplastic Syndromes\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Refractory Anemia With Excess Blasts\|Refractory Anemia With Excess Blasts in Transformation\|Refractory Anemia With Ringed Sideroblasts\|Refractory Cytopenia With Multilineage Dysplasia\|Secondary Acute Myeloid Leukemia\|Secondary Myelodysplastic Syndromes	May 2003	Phase 2
NCT00136903	Mesoblast, Inc.\|Mesoblast, Ltd.	Graft Vs Host Disease	April 27, 2005	Phase 2
NCT02206789	Aravind Eye Care System	Corneal Graft Rejection	February 2012	Not Applicable
NCT01288131	Chulalongkorn University	Anti-r-HuEpo Associated PRCA Subjects	January 2009	Phase 3
NCT00343785	Fred Hutchinson Cancer Center\|National Heart, Lung, and Blood Institute (NHLBI)	Aplastic Anemia	February 2006	Phase 2
NCT01762644	Perle Bioscience, Inc.\|Syreon Corporation	Type 1 Diabetes	August 2015	Phase 3
NCT00578370	ISDIN	Psoriasis	November 2007	Phase 1\|Phase 2
NCT02276001	Kowa Research Institute, Inc.	Healthy	June 2014	Phase 1
NCT05202145	Alexion Pharmaceuticals	Healthy	January 11, 2022	Phase 1
NCT00919503	Fred Hutchinson Cancer Center\|medac GmbH\|National Cancer Institute (NCI)\|National Heart, Lung, and Blood Institute (NHLBI)	Non-Neoplastic Hematologic and Lymphocytic Disorder	July 31, 2009	Phase 2
NCT00129961	Wyeth is now a wholly owned subsidiary of Pfizer	Skin Neoplasms\|Kidney Transplantation	August 2005	Phase 4
NCT04515329	Vishal Jhanji\|Sun Pharmaceutical Industries Limited\|University of Pittsburgh	Dry Eye	November 2022	Phase 4
NCT00009763	University of California, Davis\|National Cancer Institute (NCI)	Breast Cancer	March 2001	Phase 1
NCT00110110	The Hospital for Sick Children\|Terry Fox Foundation	Retinoblastoma	June 2004	Phase 2
NCT00171509	Novartis	Liver Transplant	May 2004	Phase 4
NCT00004482	Mayo Clinic	Myocarditis\|Giant Cell Myocarditis	December 1999	Phase 2
NCT01043640	Masonic Cancer Center, University of Minnesota	Mucopolysaccharidosis\|Hurler Syndrome\|Hunter Syndrome\|Maroteaux-Lamy Syndrome\|Sly Syndrome\|Alpha Mannosidosis\|Fucosidosis\|Aspartylglucosaminuria\|Adrenoleukodystrophy (ALD)\|Krabbe Disease\|Metachromatic Leukodystrophy (MLD)\|Sphingolipidoses\|Peroxisomal Disorders	December 2009	Phase 2
NCT00630253	Masonic Cancer Center, University of Minnesota	Fanconi Anemia	February 17, 2000	Phase 1\|Phase 2
NCT03710044	LEO Pharma	Atopic Dermatitis	August 2019	Phase 4
NCT00719849	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases	November 2005	Phase 2
NCT00301834	University of California, San Francisco\|National Cancer Institute (NCI)	Congenital Amegakaryocytic Thrombocytopenia\|Diamond-blackfan Anemia\|Leukemia\|Myelodysplastic Syndromes\|Severe Congenital Neutropenia	January 2005	Phase 2
NCT01626092	Masonic Cancer Center, University of Minnesota	Lysosomal Storage Disease\|Peroxisomal Disorder	July 11, 2012	Not Applicable
NCT00068523	Case Comprehensive Cancer Center	Chronic Myeloproliferative Disorders\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases	June 2003	Not Applicable
NCT02144857	University of Athens	Psoriasis	May 30, 2014	Phase 4
NCT04735510	Boston Sight	Ocular Surface Disease	May 2021	Phase 3
NCT01811368	Joseph Tuscano\|Spectrum Pharmaceuticals, Inc\|University of California, Davis	Refractory Non Hodgkin Lymphoma\|Relapsed Non Hodgkin Lymphoma	March 12, 2013	Phase 2
NCT03336632	Sichuan University	Leukemia, Acute\|MDS	January 1, 2019	Phase 2
NCT00005641	H. Lee Moffitt Cancer Center and Research Institute\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Graft Versus Host Disease\|Leukemia\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes	September 1997	Phase 2
NCT02655705	Seoul National University Hospital	Psoriasis	August 2014	Phase 4
NCT05245604	Taejoon Pharmaceutical Co., Ltd.	Dry Eye Syndrome	June 19, 2020	Phase 3
NCT00553098	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)\|National Heart, Lung, and Blood Institute (NHLBI)	Immunodeficiency Syndrome\|Non-Cancer Diagnosis	June 2006	Phase 2
NCT00027560	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Neoplasms	July 2001	Phase 2
NCT02688556	Sun Pharmaceutical Industries Limited	Keratoconjunctivitis Sicca	February 2016	Phase 3
NCT03382301	Hospices Civils de Lyon	Renal Artery Stenosis	August 28, 2018	Phase 2
NCT05398653	Beijing Mabworks Biotech Co., Ltd.	Primary Membranous Nephropathy	February 24, 2022	Phase 1\|Phase 2
NCT00031655	Fred Hutchinson Cancer Research Center+University of Washington Cancer Consortium\|National Cancer Institute (NCI)\|Fred Hutchinson Cancer Center	Adult Acute Lymphoblastic Leukemia in Remission\|Childhood Acute Lymphoblastic Leukemia in Remission\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Lymphoblastic Leukemia	September 2001	Phase 2
NCT05579769	St. Jude Children´s Research Hospital	Hematologic Malignancy\|Myeloid Malignancy	November 4, 2022	Phase 2
NCT02756572	University of Washington\|National Cancer Institute (NCI)	Blasts 10 Percent or More of Bone Marrow Nucleated Cells\|Chronic Myelomonocytic Leukemia-2\|High Grade Malignant Neoplasm\|Myelodysplastic Syndrome\|Myelodysplastic Syndrome With Excess Blasts-2\|Myeloid Neoplasm\|Previously Treated Myelodysplastic Syndrome\|Recurrent Acute Myeloid Leukemia\|Refractory Acute Myeloid Leukemia	September 22, 2016	Phase 2
NCT00426023	Campus Bio-Medico University\|University of Genova\|University of Padova	Vernal Keratoconjunctivitis	February 2007	Phase 3
NCT00335114	University of Alabama at Birmingham	Contact Lens Wearers With Dry Eye Syndrome	November 2005	Not Applicable
NCT05323617	Amgen	Severe Aplastic Anemia (SAA)	January 16, 2023	Phase 2
NCT00232063	Novartis Pharmaceuticals\|Novartis	Severe Atopic Dermatitis	May 2004	Phase 3
NCT02686619	Hoffmann-La Roche	Renal Transplantation	November 2004	Phase 3
NCT00004323	National Center for Research Resources (NCRR)\|University of California, Los Angeles	Aplastic Anemia	February 1995	Phase 2
NCT04127851	Taejoon Pharmaceutical Co., Ltd.	Dry Eye\|Dry Eye Syndromes	November 12, 2019	Phase 4
NCT01901471	Hospices Civils de Lyon	Acute Myocardial Infarction	September 2015	Phase 2
NCT00518375	Wyeth is now a wholly owned subsidiary of Pfizer	Kidney Transplantation	April 2000	Phase 4
NCT00895739	Federico II University\|National Cancer Institute (NCI)	Nonmalignant Neoplasm	June 2006	Phase 2
NCT02936505	Vastra Gotaland Region\|Oslo University Hospital\|Helsinki University Central Hospital\|Skane University Hospital\|Copenhagen University Hospital, Denmark	Lung Transplantation\|Allografts	October 2016	Not Applicable
NCT00006233	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Melanoma (Skin)	January 2000	Phase 2
NCT00301860	University of California, San Francisco\|National Cancer Institute (NCI)	Leukemia\|Lymphoma	January 2003	Not Applicable
NCT01706692	Swiss Dermatology Network for Targeted Therapies	Psoriasis	July 2011
NCT00038948	Wyeth is now a wholly owned subsidiary of Pfizer	Renal Transplantation	January 2002	Phase 3
NCT00521430	Asan Medical Center\|National Cancer Institute (NCI)	Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Nonmalignant Neoplasm\|Unspecified Adult Solid Tumor, Protocol Specific	April 2004	Not Applicable
NCT00919451	London School of Hygiene and Tropical Medicine\|Homes and Hospitals of St Giles\|Alert Hospital, Ethiopia\|Armauer Hansen Research Institute, Ethiopia	Leprosy	August 2010	Phase 2
NCT02998645	Novartis Pharmaceuticals\|Novartis	Severe Aplastic Anemia	May 11, 2017	Phase 2
NCT00119392	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	B-cell Chronic Lymphocytic Leukemia\|Nodal Marginal Zone B-cell Lymphoma\|Recurrent Adult Burkitt Lymphoma\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent Adult Diffuse Mixed Cell Lymphoma\|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma\|Recurrent Adult Grade III Lymphomatoid Granulomatosis\|Recurrent Adult Immunoblastic Large Cell Lymphoma\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Grade 3 Follicular Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Small Lymphocytic Lymphoma\|Splenic Marginal Zone Lymphoma\|Waldenström Macroglobulinemia	June 2004	Phase 2
NCT00268515	National Heart, Lung, and Blood Institute (NHLBI)	Lung Diseases	April 1998	Phase 2
NCT00002833	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Graft Versus Host Disease\|Leukemia\|Myelodysplastic Syndromes	October 1994	Phase 2
NCT01180036	Mayo Clinic\|Columbia University\|University of British Columbia\|Ohio State University\|Stanford University\|University of Washington\|University of Michigan\|University of Alabama at Birmingham\|Case Western Reserve University\|The Cleveland Clinic\|University of Kansas Medical Center\|University of Manchester\|University Health Network, Toronto\|University of Toronto\|CHU de Quebec-Universite Laval\|Washington University School of Medicine\|Florida International University\|University of Mississippi Medical Center\|NYU Langone Health\|Medical College of Wisconsin\|University of Arizona\|Sunnybrook Health Sciences Centre\|Applied Health Research Centre\|Fulk Family Foundation	Idiopathic Membranous Nephropathy	November 2011	Phase 2\|Phase 3
NCT03434730	Memorial Sloan Kettering Cancer Center	Acute Myeloid Leukemia\|Acute Lymphoblastic Leukemia\|Acute Leukemia\|Myelodysplastic Syndromes\|Myelodysplastic-Myeloproliferative Diseases\|Myeloproliferative Disorder\|Non Hodgkin Lymphoma\|Hodgkin Lymphoma\|Leukemia	February 7, 2018	Phase 2
NCT04328727	Novartis Pharmaceuticals\|Novartis	Severe Aplastic Anemia (SAA)	November 4, 2020	Phase 2
NCT01105650	Masonic Cancer Center, University of Minnesota	Ovarian Cancer\|Fallopian Tube Cancer\|Primary Peritoneal Cancer\|Breast Cancer	July 2010	Phase 2
NCT00005866	Southwest Oncology Group\|National Cancer Institute (NCI)	Leukemia\|Myelodysplastic Syndromes	February 2000	Phase 3
NCT02342145	Affiliated hospital of guangxi medical university,china\|Union hospital of Fujian Medical University\|Zhongshan Hospital Xiamen University\|The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School\|Kunming general Hospital of Chengdu Military Region\|First Affiliated Hospital of Guangxi Medical University	Beta-Thalassemia Major	June 2014	Phase 4
NCT00053014	Southwest Oncology Group\|National Cancer Institute (NCI)	Leukemia	April 2003	Phase 2
NCT00658359	Pfizer	Kidney Transplantation	August 2008	Phase 2
NCT00874315	Nationwide Children´s Hospital	Neuroblastoma	September 2008	Phase 2
NCT00045435	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome\|Adult Acute Megakaryoblastic Leukemia (M7)\|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)\|Adult Acute Monoblastic Leukemia (M5a)\|Adult Acute Monocytic Leukemia (M5b)\|Adult Acute Myeloblastic Leukemia With Maturation (M2)\|Adult Acute Myeloblastic Leukemia Without Maturation (M1)\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Adult Acute Myelomonocytic Leukemia (M4)\|Adult Erythroleukemia (M6a)\|Adult Pure Erythroid Leukemia (M6b)\|Secondary Acute Myeloid Leukemia	April 2002	Phase 2
NCT00078858	Fred Hutchinson Cancer Center\|National Heart, Lung, and Blood Institute (NHLBI)\|National Cancer Institute (NCI)	Accelerated Phase Chronic Myelogenous Leukemia\|Adult Acute Lymphoblastic Leukemia in Remission\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Adult Grade III Lymphomatoid Granulomatosis\|Adult Nasal Type Extranodal NK+T-cell Lymphoma\|Anaplastic Large Cell Lymphoma\|Angioimmunoblastic T-cell Lymphoma\|Childhood Acute Lymphoblastic Leukemia in Remission\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Burkitt Lymphoma\|Childhood Chronic Myelogenous Leukemia\|Childhood Diffuse Large Cell Lymphoma\|Childhood Grade III Lymphomatoid Granulomatosis\|Childhood Immunoblastic Large Cell Lymphoma\|Childhood Myelodysplastic Syndromes\|Childhood Nasal Type Extranodal NK+T-cell Lymphoma\|Childhood Renal Cell Carcinoma\|Chronic Myelomonocytic Leukemia\|Chronic Phase Chronic Myelogenous Leukemia\|Clear Cell Renal Cell Carcinoma\|Contiguous Stage II Adult Burkitt Lymphoma\|Contiguous Stage II Adult Diffuse Large Cell Lymphoma\|Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma\|Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma\|Contiguous Stage II Adult Lymphoblastic Lymphoma\|Contiguous Stage II Grade 3 Follicular Lymphoma\|Contiguous Stage II Mantle Cell Lymphoma\|de Novo Myelodysplastic Syndromes\|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue\|Hepatosplenic T-cell Lymphoma\|Juvenile Myelomonocytic Leukemia\|Myelodysplastic+Myeloproliferative Neoplasm, Unclassifiable\|Nodal Marginal Zone B-cell Lymphoma\|Noncontiguous Stage II Adult Burkitt Lymphoma\|Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma\|Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma\|Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma\|Noncontiguous Stage II Adult Lymphoblastic Lymphoma\|Noncontiguous Stage II Grade 3 Follicular Lymphoma\|Noncontiguous Stage II Mantle Cell Lymphoma\|Noncutaneous Extranodal Lymphoma\|Peripheral T-cell Lymphoma\|Post-transplant Lymphoproliferative Disorder\|Previously Treated Myelodysplastic Syndromes\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Adult Burkitt Lymphoma\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent Adult Diffuse Mixed Cell Lymphoma\|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma\|Recurrent Adult Grade III Lymphomatoid Granulomatosis\|Recurrent Adult Hodgkin Lymphoma\|Recurrent Adult Immunoblastic Large Cell Lymphoma\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Adult T-cell Leukemia+Lymphoma\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Recurrent Childhood Anaplastic Large Cell Lymphoma\|Recurrent Childhood Grade III Lymphomatoid Granulomatosis\|Recurrent Childhood Large Cell Lymphoma\|Recurrent Childhood Lymphoblastic Lymphoma\|Recurrent Childhood Small Noncleaved Cell Lymphoma\|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Grade 3 Follicular Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Mycosis Fungoides+Sezary Syndrome\|Recurrent Renal Cell Cancer\|Recurrent Small Lymphocytic Lymphoma\|Recurrent+Refractory Childhood Hodgkin Lymphoma\|Refractory Anemia\|Refractory Anemia With Ringed Sideroblasts\|Refractory Chronic Lymphocytic Leukemia\|Refractory Hairy Cell Leukemia\|Refractory Multiple Myeloma\|Relapsing Chronic Myelogenous Leukemia\|Splenic Marginal Zone Lymphoma\|Stage I Adult Burkitt Lymphoma\|Stage I Adult Diffuse Large Cell Lymphoma\|Stage I Adult Diffuse Mixed Cell Lymphoma\|Stage I Adult Immunoblastic Large Cell Lymphoma\|Stage I Adult Lymphoblastic Lymphoma\|Stage I Adult T-cell Leukemia+Lymphoma\|Stage I Childhood Anaplastic Large Cell Lymphoma\|Stage I Childhood Large Cell Lymphoma\|Stage I Childhood Lymphoblastic Lymphoma\|Stage I Childhood Small Noncleaved Cell Lymphoma\|Stage I Grade 3 Follicular Lymphoma\|Stage I Mantle Cell Lymphoma\|Stage II Adult T-cell Leukemia+Lymphoma\|Stage II Childhood Anaplastic Large Cell Lymphoma\|Stage II Childhood Large Cell Lymphoma\|Stage II Childhood Lymphoblastic Lymphoma\|Stage II Childhood Small Noncleaved Cell Lymphoma\|Stage III Adult Burkitt Lymphoma\|Stage III Adult Diffuse Large Cell Lymphoma\|Stage III Adult Diffuse Mixed Cell Lymphoma\|Stage III Adult Immunoblastic Large Cell Lymphoma\|Stage III Adult Lymphoblastic Lymphoma\|Stage III Adult T-cell Leukemia+Lymphoma\|Stage III Childhood Anaplastic Large Cell Lymphoma\|Stage III Childhood Large Cell Lymphoma\|Stage III Childhood Lymphoblastic Lymphoma\|Stage III Childhood Small Noncleaved Cell Lymphoma\|Stage III Grade 3 Follicular Lymphoma\|Stage III Mantle Cell Lymphoma\|Stage IV Adult Burkitt Lymphoma\|Stage IV Adult Diffuse Large Cell Lymphoma\|Stage IV Adult Diffuse Mixed Cell Lymphoma\|Stage IV Adult Immunoblastic Large Cell Lymphoma\|Stage IV Adult Lymphoblastic Lymphoma\|Stage IV Adult T-cell Leukemia+Lymphoma\|Stage IV Childhood Anaplastic Large Cell Lymphoma\|Stage IV Childhood Large Cell Lymphoma\|Stage IV Childhood Lymphoblastic Lymphoma\|Stage IV Childhood Small Noncleaved Cell Lymphoma\|Stage IV Grade 3 Follicular Lymphoma\|Stage IV Mantle Cell Lymphoma\|Stage IV Renal Cell Cancer\|T-cell Large Granular Lymphocyte Leukemia\|Type 1 Papillary Renal Cell Carcinoma\|Type 2 Papillary Renal Cell Carcinoma\|Untreated Adult Acute Lymphoblastic Leukemia\|Untreated Adult Acute Myeloid Leukemia\|Untreated Childhood Acute Lymphoblastic Leukemia\|Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies\|Waldenström Macroglobulinemia	September 2003	Phase 1\|Phase 2
NCT00809172	Hospices Civils de Lyon	Atopic Dermatitis	December 2008	Phase 3
NCT00031824	Children´s Oncology Group\|National Cancer Institute (NCI)	Graft Versus Host Disease	April 2002	Phase 3
NCT00821587	University of Florida\|Novartis Pharmaceuticals	Hepatitis C	June 2004	Phase 4
NCT01292226	Hoffmann-La Roche	Kidney Transplantation	December 2006	Phase 2
NCT00634920	Novartis Pharmaceuticals\|Novartis	Renal Function	March 2008	Phase 4
NCT04888741	University of Birmingham	Graft Versus Host Disease (GvHD)	February 22, 2021	Phase 2
NCT00001626	National Heart, Lung, and Blood Institute (NHLBI)\|National Institutes of Health Clinical Center (CC)	Severe Aplastic Anemia (SAA)	June 2, 1997	Phase 2
NCT00160966	University of Giessen\|Heidelberg University\|Hoffmann-La Roche\|Astellas Pharma Inc\|Novartis	Polyomavirus Infections	September 2004	Phase 4
NCT00093743	Fred Hutchinson Cancer Center\|National Heart, Lung, and Blood Institute (NHLBI)\|National Cancer Institute (NCI)	Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Myelodysplastic Syndromes\|Fanconi Anemia\|Previously Treated Myelodysplastic Syndromes	January 2000	Phase 1
NCT00245037	OHSU Knight Cancer Institute\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Neoplasms\|Precancerous Condition	June 2005	Phase 1\|Phase 2
NCT00257387	Wyeth is now a wholly owned subsidiary of Pfizer	Kidney Transplant	June 2004	Phase 1\|Phase 2
NCT00568633	Stanford University\|Genzyme, a Sanofi Company	Leukemia, Myeloid\|Leukemia\|Acute Myeloid Leukemia (AML)	August 2007	Phase 3
NCT01410448	Novartis Pharmaceuticals\|Novartis	Kidney Transplantation	November 2011	Phase 3
NCT00378534	National Heart, Lung, and Blood Institute (NHLBI)\|National Institutes of Health Clinical Center (CC)	Chronic Myelogenous Leukemia\|Acute Myelogenous Leukemia\|Chronic Lymphocytic Leukemia\|Acute Lymphoblastic Leukemia\|Myelodysplastic Syndrome	September 2006	Phase 2
NCT00139009	University of Oslo School of Pharmacy	Renal Transplantation\|Heart Transplantation	June 2005	Phase 4
NCT00363779	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Large Granular Lymphocytic Leukemia\|LGL Leukemia	June 2006	Phase 2
NCT00002961	Children´s Hospital of Philadelphia	Leukemia	October 1995	Phase 3
NCT01624805	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Aplastic Anemia\|de Novo Myelodysplastic Syndrome\|Myelodysplastic Syndrome\|Previously Treated Myelodysplastic Syndrome	June 25, 2012	Phase 2
NCT00719888	Fred Hutchinson Cancer Center	Acute Biphenotypic Leukemia\|Acute Lymphoblastic Leukemia\|Acute Myeloid Leukemia\|Burkitt Lymphoma\|Chronic Lymphocytic Leukemia\|Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Follicular Lymphoma\|Lymphoblastic Lymphoma\|Lymphoplasmacytic Lymphoma\|Mantle Cell Lymphoma\|Marginal Zone Lymphoma\|Myelodysplastic Syndrome\|Myelofibrosis\|Non-Hodgkin Lymphoma\|Plasma Cell Myeloma\|Prolymphocytic Leukemia\|Refractory Anemia\|Small Lymphocytic Lymphoma	November 18, 2005	Phase 2
NCT00611403	Allergan	Dry Eye Syndromes	December 2007	Phase 2
NCT00064701	Astellas Pharma Inc	Kidney Transplantation	June 2003	Phase 3
NCT00797030	Universidade Federal do Rio de Janeiro	Dry Eye Syndromes\|HIV Seropositivity	October 2006	Phase 4
NCT00713193	Ohio State University\|Food and Drug Administration (FDA)	Thrombotic Thrombocytopenic Purpura	November 2007	Phase 3
NCT00541814	University Hospital Birmingham\|Novartis	Chronic Allograft Nephropathy	October 2007	Phase 4
NCT00070291	Eastern Cooperative Oncology Group\|National Cancer Institute (NCI)	Lymphoma	September 2005	Phase 2
NCT00003954	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Refractory Multiple Myeloma\|Stage I Multiple Myeloma\|Stage II Multiple Myeloma\|Stage III Multiple Myeloma	March 1999	Phase 1\|Phase 2
NCT00987207	Hospices Civils de Lyon	Aortic Valvular Surgery	October 2008	Phase 3
NCT00977977	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)\|National Institutes of Health Clinical Center (CC)	Nephrotic Syndrome\|Proteinuria\|Autoimmune Disease\|Glomerular Disease\|Membranous Glomerulonephritis	December 22, 2010	Phase 2
NCT01289301	Hannover Medical School	Disorder Related to Renal Transplantation\|Immunosuppression Related Infectious Disease\|Virus Diseases	October 2011	Phase 4
NCT00806598	M.D. Anderson Cancer Center\|Genzyme, a Sanofi Company	Myelodysplastic Syndrome\|Aplastic Anemia	May 2005	Phase 2
NCT00375895	Rennes University Hospital\|Novartis	Chronic Hepatitis C\|Evidence of Liver Transplantation	June 2006	Phase 3
NCT00784719	Pfizer	Dry Eye Syndromes	November 2008	Phase 1\|Phase 2
NCT00003145	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Accelerated Phase of Disease\|Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Chronic Phase of Disease\|Recurrent Disease	August 1997	Phase 2
NCT00150891	University of Giessen\|Heidelberg University\|Astellas Pharma Inc\|Novartis\|Fresenius AG\|Hoffmann-La Roche\|Biotest	Renal Failure, Chronic	January 1998
NCT00425802	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Leukemia\|Lymphoma	November 28, 2006	Phase 2
NCT00658320	Novartis	Kidney Transplantation	February 2008	Phase 3
NCT04392531	Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz	COVID19 Infection	April 16, 2020	Phase 4
NCT00729768	Genentech, Inc.	Kidney Transplantation		Phase 2\|Phase 3
NCT00290641	Masonic Cancer Center, University of Minnesota\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Leukemia\|Lymphoma\|Myelodysplastic Syndromes	April 2001	Not Applicable
NCT00420537	University of Bologna	Kidney Dysfunction\|Heart Transplantation	September 2006	Phase 4
NCT01020734	Asan Medical Center	Leukemia	May 2011	Phase 2
NCT03768609	Janssen-Cilag International NV	Healthy	December 6, 2018	Phase 1
NCT01526850	Cancer Institute and Hospital, Chinese Academy of Medical Sciences\|Zhejiang University\|Chinese PLA General Hospital\|307 Hospital of PLA\|Peking Union Medical College	Chronic Graft Versus Host Disease	February 2012	Phase 2\|Phase 3
NCT00185614	Wen-Kai Weng\|Stanford University	Blood Cancer\|Multiple Myeloma	August 2000	Phase 2
NCT04743739	Peking Union Medical College Hospital\|Beijing Tongren Hospital\|Chinese Academy of Medical Sciences, Fuwai Hospital\|The Luhe Teaching Hospital of the Capital Medical University\|The Seventh Affiliated Hospital of Sun Yat-sen University\|First Affiliated Hospital of Xinjiang Medical University\|Nanyang Nanshi Hospital of Henan University\|Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.	Idiopathic Membranous Nephropathy	April 14, 2021	Phase 3
NCT05219656	Tampere University Hospital	Ulcerative Colitis Acute	January 1, 2009
NCT01033552	Masonic Cancer Center, University of Minnesota	Epidermolysis Bullosa	January 2010	Phase 1\|Phase 2
NCT00317408	European Inter-group Cooperation on Childhood and Adolescent Non Hodgkin Lymphoma\|National Cancer Institute (NCI)	Lymphoma	April 2004	Not Applicable
NCT00195468	Wyeth is now a wholly owned subsidiary of Pfizer	Kidney Failure\|Graft vs Host Disease	March 2004	Phase 4
NCT00755781	APT Pharmaceuticals, Inc.	Lung Transplant	September 2008	Phase 3
NCT01990898	The Cleveland Clinic	Interstitial Cystitis	November 2013	Phase 2
NCT00896493	Stanford University	Mycoses\|Sezary Syndrome\|Lymphoma, T-Cell, Cutaneous\|Bone Marrow Transplant Failure\|Lymphoma, Non-Hodgkin\|Cutaneous T-cell Lymphoma	May 2009	Phase 2
NCT00009750	University of California, Davis\|National Cancer Institute (NCI)	Prostate Cancer	March 2001	Phase 1
NCT01718652	Johnson & Johnson Pharmaceutical Research & Development, L.L.C.	Healthy	February 2011	Phase 1
NCT00048165	Hoffmann-La Roche	Heart Transplantation	August 1999	Phase 4
NCT03136237	BioCryst Pharmaceuticals	Hereditary Angioedema	February 17, 2017	Phase 1
NCT01990118	Penang Hospital, Malaysia	End Stage Renal Failure	November 2004	Phase 4
NCT00003950	University of Chicago\|National Cancer Institute (NCI)	Colorectal Cancer	January 2000	Phase 2
NCT00397813	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)\|National Heart, Lung, and Blood Institute (NHLBI)	Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative\|Chronic Myelomonocytic Leukemia\|de Novo Myelodysplastic Syndrome\|Essential Thrombocythemia\|Myeloproliferative Neoplasm\|Paroxysmal Nocturnal Hemoglobinuria\|Polycythemia Vera\|Polycythemia Vera, Post-Polycythemic Myelofibrosis Phase\|Primary Myelofibrosis\|Refractory Anemia\|Refractory Anemia With Excess Blasts\|Refractory Anemia With Ring Sideroblasts\|Refractory Cytopenia With Multilineage Dysplasia\|Refractory Cytopenia With Multilineage Dysplasia and Ring Sideroblasts	January 2006	Phase 2
NCT00182559	Medical University of Vienna	End Stage Renal Disease	April 2004	Phase 4
NCT01434472	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Post-Transplant Lymphoproliferative Disorder\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent B-Cell Non-Hodgkin Lymphoma\|Recurrent Burkitt Lymphoma\|Refractory B-Cell Non-Hodgkin Lymphoma\|Refractory Burkitt Lymphoma\|Refractory Diffuse Large B-Cell Lymphoma	November 16, 2011	Phase 2
NCT00008450	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)\|National Heart, Lung, and Blood Institute (NHLBI)	Adenosine Deaminase Deficiency\|Autosomal Recessive Disorder\|Immune System Disorder\|Purine-Nucleoside Phosphorylase Deficiency\|Severe Combined Immunodeficiency\|Severe Combined Immunodeficiency With Absence of T and B Cells\|X-Linked Severe Combined Immunodeficiency	August 11, 1997	Phase 1
NCT02876250	Hospices Civils de Lyon	Lung Transplantation	January 2017	Phase 3
NCT00482053	Stanford University	Lymphoma, B-cell\|Lymphoma, Non-Hodgkin\|Diffuse Large B-cell Lymphoma (DLBCL)\|Malignant Lymphoma, Non-Hodgkin	October 2006	Phase 2
NCT00741455	Dartmouth-Hitchcock Medical Center	Hematologic Malignancies	June 2004	Not Applicable
NCT00022126	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	November 2002	Phase 2
NCT00058825	Baylor College of Medicine\|The Methodist Hospital Research Institute	Hematologic Malignancies	August 2000	Phase 1\|Phase 2
NCT05605314	Peking University Third Hospital	Dry Eye	January 1, 2021
NCT00006968	Jonsson Comprehensive Cancer Center\|National Cancer Institute (NCI)	Kidney Cancer	September 2000	Phase 1\|Phase 2
NCT00047060	National Heart, Lung, and Blood Institute (NHLBI)\|National Institutes of Health Clinical Center (CC)	Mycosis Fungoides\|Sezary Syndrome	July 30, 2002	Phase 1\|Phase 2
NCT02461121	The Affiliated Hospital of the Chinese Academy of Military Medical Sciences	Acute Myeloid Leukemia	May 2004	Phase 3
NCT00790439	National Institute of Allergy and Infectious Diseases (NIAID)\|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	Diabetes Mellitus, Type I	July 2008	Phase 2
NCT00243009	OHSU Knight Cancer Institute\|National Cancer Institute (NCI)	Kidney Cancer	June 2005	Phase 2
NCT00024050	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Leukemia\|Myelodysplastic Syndromes	February 2001	Phase 2
NCT00556257	Pfizer	Kidney Transplantation	August 2007	Phase 2
NCT00154193	Novartis Pharmaceuticals\|Novartis	Heart and Lung Transplant	June 2004	Phase 4
NCT02397213	Region Skane\|NeuroVive Pharmaceutical AB	Acute Kidney Injury	April 2015	Phase 2
NCT00633373	APT Pharmaceuticals, Inc.	Lung Transplant
NCT00075478	Fred Hutchinson Cancer Center\|National Heart, Lung, and Blood Institute (NHLBI)\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia in Remission\|Acute Myeloid Leukemia in Remission\|Aggressive Non-Hodgkin Lymphoma\|Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Diffuse Large B-Cell Lymphoma\|Hematopoietic and Lymphoid Cell Neoplasm\|Indolent Non-Hodgkin Lymphoma\|Mantle Cell Lymphoma\|Myelodysplastic+Myeloproliferative Neoplasm\|Plasma Cell Myeloma\|Refractory Chronic Lymphocytic Leukemia\|Refractory Hodgkin Lymphoma\|Waldenstrom Macroglobulinemia	October 2003	Phase 3
NCT00002832	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Leukemia\|Myelodysplastic Syndromes	August 1995	Phase 1\|Phase 2
NCT03970096	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Acute Biphenotypic Leukemia\|Acute Leukemia of Ambiguous Lineage\|Acute Lymphoblastic Leukemia\|Acute Myeloid Leukemia\|Acute Undifferentiated Leukemia\|Blastic Plasmacytoid Dendritic Cell Neoplasm\|Lymphoblastic Lymphoma\|Mixed Phenotype Acute Leukemia\|Acute Leukemia\|Hematopoietic and Lymphoid Cell Neoplasm	November 19, 2019	Phase 2
NCT04009525	First Affiliated Hospital of Guangxi Medical University\|Peking University People´s Hospital\|Ruijin Hospital\|The 923th Hospital of People´s Liberation Army\|Fourth Affiliated Hospital of Guangxi Medical University\|Liuzhou General Hospital\|Hainan General Hospital\|The Affiliated Hospital Of Guizhou Medical University\|The First People´s Hospital of Yunnan	Thalassemia Major	June 1, 2019	Phase 4
NCT00319878	Office of Rare Diseases (ORD)\|Rare Diseases Clinical Research Network	Anemia, Aplastic	May 2006	Phase 1\|Phase 2
NCT00402168	Bristol-Myers Squibb	Renal Transplant	January 2007	Phase 2
NCT00195624	National Heart, Lung, and Blood Institute (NHLBI)\|National Institutes of Health Clinical Center (CC)	Severe Aplastic Anemia, Refractory\|Severe Aplastic Anemia, Relapse	September 15, 2005	Phase 2
NCT04426240	Samsung Medical Center	Dry Eye Syndromes	August 3, 2020	Phase 4
NCT05303727	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	Neuroblastoma	August 2022	Phase 2
NCT00066417	National Heart, Lung, and Blood Institute (NHLBI)\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Leukemia\|Myelodysplastic+Myeloproliferative Diseases		Phase 2
NCT01479881	Tibotec Pharmaceuticals, Ireland	Hepatitis C Virus	October 2011	Phase 1
NCT02799888	Affiliated Hospital to Academy of Military Medical Sciences	Graft-versus-host Disease\|Hematopoietic Stem Cell Transplantation	April 2014	Phase 2
NCT03095547	F2G Biotech GmbH\|Bio-Kinetic Europe, Ltd.	Invasive Aspergillosis	May 2017	Phase 1
NCT02005562	Hoffmann-La Roche	Kidney Transplantation	May 2006	Phase 3
NCT04835623	Center for Ophthalmic and Vision Research, LLC\|Sun Pharmaceutical Industries Limited	Dry Eye\|Dry Eye Syndromes\|Sjogren´s Syndrome	June 21, 2021	Phase 4
NCT03013933	City of Hope Medical Center\|National Cancer Institute (NCI)	Recurrent Hodgkin Lymphoma\|Refractory Hodgkin Lymphoma	May 3, 2017	Phase 1
NCT02864706	Novartis Pharmaceuticals\|Novartis	Heart Transplantation	January 18, 2016	Phase 4
NCT00766909	University of Aarhus	Complications of Transplanted Organs and Tissue\|Diabetes Mellitus Nos New Onset	March 2008	Phase 4
NCT00286624	University of Minnesota\|Juvenile Diabetes Research Foundation\|National Institutes of Health (NIH)\|Novartis	Type 1 Diabetes Mellitus\|Hypoglycemia	March 2003	Phase 1\|Phase 2
NCT03246906	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)\|National Institutes of Health (NIH)	Acute Lymphoblastic Leukemia\|Acute Myeloid Leukemia\|Aggressive Non-Hodgkin Lymphoma\|Chronic Lymphocytic Leukemia\|Diffuse Large B-Cell Lymphoma\|Mantle Cell Lymphoma\|Myelodysplastic Syndrome\|Myelodysplastic+Myeloproliferative Neoplasm\|Prolymphocytic Leukemia\|Recurrent Chronic Lymphocytic Leukemia\|Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Recurrent Hodgkin Lymphoma\|Recurrent Plasma Cell Myeloma\|Recurrent Small Lymphocytic Lymphoma\|Recurrent Waldenstrom Macroglobulinemia\|Hematologic and Lymphocytic Disorder\|Blastic Plasmacytoid Dendritic Cell Neoplasm	September 11, 2017	Phase 2
NCT00553735	Massachusetts Eye and Ear Infirmary	Dry Eye	August 2007	Phase 4
NCT01211327	University Hospital, Ghent\|Funds for Research in Ophthalmology (FRO) of Belgium\|Novartis	Vernal Keratoconjunctivitis	July 2008	Phase 4
NCT04636918	Singapore Eye Research Institute	Leukemia (Both ALL and AML)\|MDS-EB-1	November 28, 2019	Phase 4
NCT00389870	University of Leeds	Colorectal Cancer	December 2006	Phase 3
NCT00027924	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Leukemia\|Myelodysplastic Syndromes	October 2001	Phase 2
NCT00005803	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Prolymphocytic Leukemia\|Recurrent Adult Hodgkin Lymphoma\|Recurrent Childhood Hodgkin Lymphoma\|Recurrent Childhood Non-Hodgkin Lymphoma\|Recurrent Chronic Lymphocytic Leukemia\|Recurrent Non-Hodgkin Lymphoma\|Recurrent Small Lymphocytic Lymphoma\|Refractory Childhood Hodgkin Lymphoma\|Refractory Chronic Lymphocytic Leukemia\|Refractory Hodgkin Lymphoma\|Refractory Non-Hodgkin Lymphoma\|Refractory Small Lymphocytic Lymphoma\|T-Cell Chronic Lymphocytic Leukemia\|T-Cell Prolymphocytic Leukemia	September 1999	Phase 1\|Phase 2
NCT02707393	St. Anna Kinderkrebsforschung	Chronic Myeloid Leukemia	April 30, 2009	Phase 2\|Phase 3
NCT00008307	Herbert Irving Comprehensive Cancer Center\|National Cancer Institute (NCI)	Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes	April 1998	Phase 2
NCT02907554	University Hospital, Clermont-Ferrand\|University Hospital, Estaing\|Centre Hospitalier Universitaire de Nice\|Groupe Hospitalier Pitie-Salpetriere\|Centre Hospitalier Universitaire de N?mes\|University Hospital, Montpellier\|Hôtel Dieu (Nantes)\|Poitiers University Hospital\|University Hospital, Toulouse\|Hôpital de la Timone	Brain Death\|Kidney Transplantation	December 19, 2017	Phase 4
NCT04877288	Bristol-Myers Squibb	Renal Allograft Recipients	July 21, 2021	Phase 3
NCT00354172	Masonic Cancer Center, University of Minnesota	Leukemia\|Myelodysplastic Syndromes	February 2006	Phase 2
NCT00149994	Novartis Pharmaceuticals\|Novartis	Liver Transplant	December 2002	Phase 4
NCT00148746	Technische Universität Dresden	Moderate to Severe Atopic Dermatitis	May 2004	Not Applicable
NCT00365287	Masonic Cancer Center, University of Minnesota\|National Cancer Institute (NCI)	Breast Cancer\|Kidney Cancer\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes	June 2000	Phase 1\|Phase 2
NCT00005851	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Recurrent Renal Cell Cancer\|Stage IV Renal Cell Cancer	February 2000	Phase 1\|Phase 2
NCT02617667	Novaliq GmbH	Dry Eye Syndromes	January 2016	Phase 2
NCT00944749	National Heart, Lung, and Blood Institute (NHLBI)\|National Institutes of Health Clinical Center (CC)	Anemia, Aplastic\|Anemia, Hypoplastic	August 31, 2009	Phase 2
NCT00637143	Astellas Pharma Inc\|Astellas Pharma Canada, Inc.	Renal Transplantation\|Chronic Renal Allograft Failure	April 1999	Phase 4
NCT00002792	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Leukemia\|Myelodysplastic+Myeloproliferative Diseases	June 1996	Phase 2
NCT00350545	Stanford University	Graft vs Host Disease	August 2006	Not Applicable
NCT00332462	Novartis Pharmaceuticals\|Novartis	Liver Transplantation	May 2006	Phase 4
NCT00016419	Southwest Oncology Group\|National Cancer Institute (NCI)	Leukemia\|Myelodysplastic Syndromes	August 2001	Phase 2
NCT03150134	Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine	Acute Myeloid Leukemia\|Disorder Related to Bone Marrow Transplantation	January 1, 2010	Phase 4
NCT04424862	Beijing Friendship Hospital	Efficacy	June 9, 2020	Phase 4
NCT00990795	The University of Texas Health Science Center, Houston	Cardiac Surgical Procedures	April 2010	Phase 1
NCT00300274	Novartis Pharmaceuticals\|Novartis	Graft Rejection	January 2006	Phase 3
NCT00427661	University of Pittsburgh	Sickle Cell Disease\|Thalassemia\|Hemoglobinopathies	June 2002	Not Applicable
NCT04895423	National Medical Research Center for Children´s Health, Russian Federation	Atopic Dermatitis	November 25, 2021	Phase 4
NCT00112593	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Accelerated Phase Chronic Myelogenous Leukemia\|Acute Undifferentiated Leukemia\|Adult Acute Lymphoblastic Leukemia in Remission\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Adult Grade III Lymphomatoid Granulomatosis\|Adult Nasal Type Extranodal NK+T-cell Lymphoma\|Aggressive NK-cell Leukemia\|AIDS-related Diffuse Large Cell Lymphoma\|AIDS-related Diffuse Mixed Cell Lymphoma\|AIDS-related Diffuse Small Cleaved Cell Lymphoma\|AIDS-related Immunoblastic Large Cell Lymphoma\|AIDS-related Lymphoblastic Lymphoma\|AIDS-related Peripheral+Systemic Lymphoma\|AIDS-related Primary CNS Lymphoma\|AIDS-related Small Noncleaved Cell Lymphoma\|Anaplastic Large Cell Lymphoma\|Angioimmunoblastic T-cell Lymphoma\|Blastic Phase Chronic Myelogenous Leukemia\|Childhood Acute Lymphoblastic Leukemia in Remission\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Burkitt Lymphoma\|Childhood Chronic Myelogenous Leukemia\|Childhood Diffuse Large Cell Lymphoma\|Childhood Grade III Lymphomatoid Granulomatosis\|Childhood Immunoblastic Large Cell Lymphoma\|Childhood Myelodysplastic Syndromes\|Childhood Nasal Type Extranodal NK+T-cell Lymphoma\|Chronic Eosinophilic Leukemia\|Chronic Myelomonocytic Leukemia\|Chronic Neutrophilic Leukemia\|Chronic Phase Chronic Myelogenous Leukemia\|Contiguous Stage II Adult Burkitt Lymphoma\|Contiguous Stage II Adult Diffuse Large Cell Lymphoma\|Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma\|Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma\|Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma\|Contiguous Stage II Adult Lymphoblastic Lymphoma\|Contiguous Stage II Grade 1 Follicular Lymphoma\|Contiguous Stage II Grade 2 Follicular Lymphoma\|Contiguous Stage II Grade 3 Follicular Lymphoma\|Contiguous Stage II Mantle Cell Lymphoma\|Contiguous Stage II Marginal Zone Lymphoma\|Contiguous Stage II Small Lymphocytic Lymphoma\|Cutaneous B-cell Non-Hodgkin Lymphoma\|Essential Thrombocythemia\|Extramedullary Plasmacytoma\|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue\|Hepatosplenic T-cell Lymphoma\|HIV Infection\|HIV-associated Hodgkin Lymphoma\|Intraocular Lymphoma\|Isolated Plasmacytoma of Bone\|Juvenile Myelomonocytic Leukemia\|Mast Cell Leukemia\|Meningeal Chronic Myelogenous Leukemia\|Myelodysplastic+Myeloproliferative Neoplasm, Unclassifiable\|Myeloid+NK-cell Acute Leukemia\|Nodal Marginal Zone B-cell Lymphoma\|Noncontiguous Stage II Adult Burkitt Lymphoma\|Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma\|Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma\|Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma\|Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma\|Noncontiguous Stage II Adult Lymphoblastic Lymphoma\|Noncontiguous Stage II Grade 1 Follicular Lymphoma\|Noncontiguous Stage II Grade 2 Follicular Lymphoma\|Noncontiguous Stage II Grade 3 Follicular Lymphoma\|Noncontiguous Stage II Mantle Cell Lymphoma\|Noncontiguous Stage II Marginal Zone Lymphoma\|Noncontiguous Stage II Small Lymphocytic Lymphoma\|Noncutaneous Extranodal Lymphoma\|Peripheral T-cell Lymphoma\|Polycythemia Vera\|Post-transplant Lymphoproliferative Disorder\|Previously Treated Myelodysplastic Syndromes\|Primary Central Nervous System Lymphoma\|Primary Myelofibrosis\|Primary Systemic Amyloidosis\|Progressive Hairy Cell Leukemia, Initial Treatment\|Prolymphocytic Leukemia\|Secondary Acute Myeloid Leukemia\|Secondary Myelodysplastic Syndromes\|Small Intestine Lymphoma\|Splenic Marginal Zone Lymphoma\|Stage 0 Chronic Lymphocytic Leukemia\|Stage I Adult Burkitt Lymphoma\|Stage I Adult Diffuse Large Cell Lymphoma\|Stage I Adult Diffuse Mixed Cell Lymphoma\|Stage I Adult Diffuse Small Cleaved Cell Lymphoma\|Stage I Adult Hodgkin Lymphoma\|Stage I Adult Immunoblastic Large Cell Lymphoma\|Stage I Adult Lymphoblastic Lymphoma\|Stage I Adult T-cell Leukemia+Lymphoma\|Stage I Childhood Anaplastic Large Cell Lymphoma\|Stage I Childhood Hodgkin Lymphoma\|Stage I Childhood Large Cell Lymphoma\|Stage I Childhood Lymphoblastic Lymphoma\|Stage I Childhood Small Noncleaved Cell Lymphoma\|Stage I Chronic Lymphocytic Leukemia\|Stage I Cutaneous T-cell Non-Hodgkin Lymphoma\|Stage I Grade 1 Follicular Lymphoma\|Stage I Grade 2 Follicular Lymphoma\|Stage I Grade 3 Follicular Lymphoma\|Stage I Mantle Cell Lymphoma\|Stage I Marginal Zone Lymphoma\|Stage I Multiple Myeloma\|Stage I Small Lymphocytic Lymphoma\|Stage IA Mycosis Fungoides+Sezary Syndrome\|Stage IB Mycosis Fungoides+Sezary Syndrome\|Stage II Adult Hodgkin Lymphoma\|Stage II Adult T-cell Leukemia+Lymphoma\|Stage II Childhood Anaplastic Large Cell Lymphoma\|Stage II Childhood Hodgkin Lymphoma\|Stage II Childhood Large Cell Lymphoma\|Stage II Childhood Lymphoblastic Lymphoma\|Stage II Childhood Small Noncleaved Cell Lymphoma\|Stage II Chronic Lymphocytic Leukemia\|Stage II Cutaneous T-cell Non-Hodgkin Lymphoma\|Stage II Multiple Myeloma\|Stage IIA Mycosis Fungoides+Sezary Syndrome\|Stage IIB Mycosis Fungoides+Sezary Syndrome\|Stage III Adult Burkitt Lymphoma\|Stage III Adult Diffuse Large Cell Lymphoma\|Stage III Adult Diffuse Mixed Cell Lymphoma\|Stage III Adult Diffuse Small Cleaved Cell Lymphoma\|Stage III Adult Hodgkin Lymphoma\|Stage III Adult Immunoblastic Large Cell Lymphoma\|Stage III Adult Lymphoblastic Lymphoma\|Stage III Adult T-cell Leukemia+Lymphoma\|Stage III Childhood Anaplastic Large Cell Lymphoma\|Stage III Childhood Hodgkin Lymphoma\|Stage III Childhood Large Cell Lymphoma\|Stage III Childhood Lymphoblastic Lymphoma\|Stage III Childhood Small Noncleaved Cell Lymphoma\|Stage III Chronic Lymphocytic Leukemia\|Stage III Cutaneous T-cell Non-Hodgkin Lymphoma\|Stage III Grade 1 Follicular Lymphoma\|Stage III Grade 2 Follicular Lymphoma\|Stage III Grade 3 Follicular Lymphoma\|Stage III Mantle Cell Lymphoma\|Stage III Marginal Zone Lymphoma\|Stage III Multiple Myeloma\|Stage III Small Lymphocytic Lymphoma\|Stage IIIA Mycosis Fungoides+Sezary Syndrome\|Stage IIIB Mycosis Fungoides+Sezary Syndrome\|Stage IV Adult Burkitt Lymphoma\|Stage IV Adult Diffuse Large Cell Lymphoma\|Stage IV Adult Diffuse Mixed Cell Lymphoma\|Stage IV Adult Diffuse Small Cleaved Cell Lymphoma\|Stage IV Adult Hodgkin Lymphoma\|Stage IV Adult Immunoblastic Large Cell Lymphoma\|Stage IV Adult Lymphoblastic Lymphoma\|Stage IV Adult T-cell Leukemia+Lymphoma\|Stage IV Childhood Anaplastic Large Cell Lymphoma\|Stage IV Childhood Hodgkin Lymphoma\|Stage IV Childhood Large Cell Lymphoma\|Stage IV Childhood Lymphoblastic Lymphoma\|Stage IV Childhood Small Noncleaved Cell Lymphoma\|Stage IV Chronic Lymphocytic Leukemia\|Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma\|Stage IV Grade 1 Follicular Lymphoma\|Stage IV Grade 2 Follicular Lymphoma\|Stage IV Grade 3 Follicular Lymphoma\|Stage IV Mantle Cell Lymphoma\|Stage IV Marginal Zone Lymphoma\|Stage IV Small Lymphocytic Lymphoma\|Stage IVA Mycosis Fungoides+Sezary Syndrome\|Stage IVB Mycosis Fungoides+Sezary Syndrome\|T-cell Large Granular Lymphocyte Leukemia\|Testicular Lymphoma\|Unspecified Adult Solid Tumor, Protocol Specific\|Unspecified Childhood Solid Tumor, Protocol Specific\|Waldenström Macroglobulinemia	November 1999	Not Applicable
NCT00928018	Dana-Farber Cancer Institute\|Brigham and Women´s Hospital\|Massachusetts General Hospital\|National Cancer Institute (NCI)	Non-hodgkin Lymphoma\|Hodgkin Lymphoma	June 2009	Phase 3
NCT01273207	National Heart, Lung, and Blood Institute (NHLBI)\|National Institutes of Health Clinical Center (CC)	Bronchiolitis Obliterans\|Constructive Bronchiolitis\|Graft Versus Host Disease\|Bronchiolitis, Exudative\|Bronchiolitis, Proliferative\|Graft-Versus-Host Disease	March 2, 2012	Phase 2
NCT00438360	Novartis Pharmaceuticals\|Novartis	Chronic Plaque Psoriasis	May 2006	Phase 3
NCT00066794	Southwest Oncology Group\|National Cancer Institute (NCI)	Leukemia	July 2004	Phase 2
NCT00663455	University of Erlangen-Nürnberg Medical School	Kidney Transplant	December 2008	Phase 4
NCT04705584	Assiut University	Vernal Keratoconjunctivitis	January 2021	Not Applicable
NCT04149678	Celgene	Healthy Volunteers	October 4, 2019	Phase 1
NCT00574496	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Lymphoma	November 13, 2007	Phase 2
NCT00163657	Baylor Research Institute\|Baylor Health Care System\|Emory University\|University of Southern California\|Mayo Clinic - Scottsdale+Phoenix, Arizona\|New York Presbyterian Hospital\|Oregon Health and Science University\|New York University\|University of Cincinnati\|University of Alabama at Birmingham\|The University of Texas Health Science Center at San Antonio\|University of Chicago\|University of California, San Francisco\|Mayo Clinic - Rochester, Minnesota\|Medical University of South Carolina\|University of Virginia\|Lahey Clinic\|University of Medicine and Dentistry of New Jersey\|Northwestern Memorial Hospital	End Stage Liver Disease\|Hepatitis C	July 2002	Phase 4
NCT00862979	Novartis Pharmaceuticals\|Novartis	Heart Transplantation	February 24, 2009	Phase 4
NCT04172961	Toyos Clinic\|Sun Pharmaceutical Industries Limited	Dry Eye	February 1, 2020	Phase 4
NCT00483756	Pfizer	Kidney Transplantation	August 2007	Phase 2
NCT00783107	University of Pittsburgh	Chronic Obstructive Pulmonary Disease	October 2007	Phase 1
NCT00003116	Case Comprehensive Cancer Center\|National Cancer Institute (NCI)	Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases	May 1997	Phase 2
NCT00594308	Indiana University	Acute Myelogenous Leukemia\|Acute Lymphocytic Leukemia\|Chronic Myelogenous Leukemia\|Chronic Lymphocytic Leukemia\|Myelodysplasia\|Lymphoma, Non-Hodgkin´s\|Mantle-Cell Lymphoma\|Hodgkin´s Disease\|Multiple Myeloma\|Myelofibrosis	October 2007	Not Applicable
NCT00425308	Novartis Pharmaceuticals\|Novartis	Renal Transplantation	October 2006	Phase 3
NCT04237987	Peking University People´s Hospital	Inflammatory Myopathy	January 21, 2020	Phase 2
NCT00004232	Northwestern University\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Graft Versus Host Disease\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Precancerous+Nonmalignant Condition	October 1999	Phase 1
NCT04714099	Alexandria University	Dry Eye	January 1, 2015	Phase 3
NCT00812123	University Hospital, Basel, Switzerland\|Wyeth is now a wholly owned subsidiary of Pfizer	Kidney Transplantation\|Chronic Kidney Disease	January 2001	Phase 4
NCT01080560	Panacea Biotec Ltd	Healthy Volunteers	August 2007	Not Applicable
NCT00357565	Masonic Cancer Center, University of Minnesota	Leukemia\|Myelodysplastic Syndromes\|Childhood Acute Myeloid Leukemia in Remission\|Recurrent Childhood Acute Myeloid Leukemia\|Secondary Acute Myeloid Leukemia\|Childhood Acute Lymphoblastic Leukemia in Remission\|Previously Treated Myelodysplastic Syndrome\|Secondary Myelodysplastic Syndrome\|Refractory Anemia With Excess Blasts in Transformation\|Refractory Anemia With Excess Blasts\|Refractory Anemia\|De Novo Myelodysplastic Syndrome\|Childhood Myelodysplastic Syndrome	November 2005	Phase 2
NCT00002759	National Cancer Institute (NCI)	Drug+Agent Toxicity by Tissue+Organ\|Lymphoma\|Neutropenia\|Small Intestine Cancer\|Unspecified Adult Solid Tumor, Protocol Specific	June 1996	Phase 1
NCT02280421	Maruho Europe Limited	Healthy	October 2014	Phase 1
NCT00818194	Astellas Pharma Inc\|Astellas Pharma Canada, Inc.	Healthy	April 2008	Phase 1
NCT00579527	Enzyvant Therapeutics GmBH\|National Institutes of Health (NIH)\|National Institute of Allergy and Infectious Diseases (NIAID)\|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	DiGeorge Anomaly\|Complete DiGeorge Anomaly\|Complete Atypical DiGeorge Anomaly\|Complete DiGeorge Syndrome\|Complete Atypical DiGeorge Syndrome	December 19, 2005	Phase 1\|Phase 2
NCT00377325	University of Rochester\|National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)	Psoriasis	June 2007	Phase 2
NCT02016625	Boehringer Ingelheim	Healthy	December 2013	Phase 1
NCT04488081	QuantumLeap Healthcare Collaborative\|University of California, San Francisco\|University of Pennsylvania\|Emory University\|University of Alabama at Birmingham\|University of Colorado, Denver\|University of Southern California\|Yale University\|Columbia University\|Wake Forest University Health Sciences\|Sanford Health\|Long Beach Memorial Medical Center\|Georgetown University\|University of California, Davis\|Hoag Memorial Hospital Presbyterian\|University of Iowa\|Main Line Health\|Northwestern University\|DHR Health Institute for Research and Development\|Mercy Hospital Springfield\|University of California, Irvine\|Spectrum Health Hospitals\|Kaiser Permanente\|University of Rochester\|University of Michigan\|West Virginia University\|Stamford Hospital\|University of Miami\|University Hospitals Cleveland Medical Center\|Logan Health\|Virtua Memorial Hospital Mount Holly\|Sanford USD Medical Center\|UC Irvine Medical Center\|University of Florida Health Shands Hospital\|M.D. Anderson Cancer Center	COVID-19	July 31, 2020	Phase 2
NCT00686556	Masonic Cancer Center, University of Minnesota	Acute Lymphoblastic Leukemia\|Myelodysplastic Syndrome\|Multiple Myeloma	August 2012	Phase 1
NCT01650662	Mario Negri Institute for Pharmacological Research\|Heart Care Foundation	Acute Myocardial Infarction	January 2012	Phase 3
NCT00051311	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Hematologic Neoplasms	January 3, 2003	Phase 2
NCT00195273	Wyeth is now a wholly owned subsidiary of Pfizer	Graft vs Host Disease\|Kidney Transplantation	November 2004	Phase 3
NCT00000880	National Institute of Allergy and Infectious Diseases (NIAID)	HIV Infections		Phase 2
NCT00002688	University Medical Center Groningen\|National Cancer Institute (NCI)	Leukemia	February 1995	Phase 2
NCT01093586	Case Comprehensive Cancer Center	Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome\|Adult Acute Lymphoblastic Leukemia in Remission\|Adult Acute Megakaryoblastic Leukemia (M7)\|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)\|Adult Acute Monoblastic Leukemia (M5a)\|Adult Acute Monocytic Leukemia (M5b)\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Erythroleukemia (M6a)\|Adult Nasal Type Extranodal NK+T-cell Lymphoma\|Adult Pure Erythroid Leukemia (M6b)\|B-cell Adult Acute Lymphoblastic Leukemia\|B-cell Childhood Acute Lymphoblastic Leukemia\|Blastic Phase Chronic Myelogenous Leukemia\|Burkitt Lymphoma\|Childhood Acute Erythroleukemia (M6)\|Childhood Acute Lymphoblastic Leukemia in Remission\|Childhood Acute Megakaryocytic Leukemia (M7)\|Childhood Acute Minimally Differentiated Myeloid Leukemia (M0)\|Childhood Acute Monoblastic Leukemia (M5a)\|Childhood Acute Monocytic Leukemia (M5b)\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Chronic Myelogenous Leukemia\|Childhood Diffuse Large Cell Lymphoma\|Childhood Immunoblastic Large Cell Lymphoma\|Childhood Myelodysplastic Syndromes\|Childhood Nasal Type Extranodal NK+T-cell Lymphoma\|Chronic Myelomonocytic Leukemia\|Chronic Phase Chronic Myelogenous Leukemia\|Cutaneous B-cell Non-Hodgkin Lymphoma\|de Novo Myelodysplastic Syndromes\|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue\|Juvenile Myelomonocytic Leukemia\|Myelodysplastic+Myeloproliferative Neoplasm, Unclassifiable\|Nodal Marginal Zone B-cell Lymphoma\|Previously Treated Myelodysplastic Syndromes\|Prolymphocytic Leukemia\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Adult Burkitt Lymphoma\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent Adult Diffuse Mixed Cell Lymphoma\|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma\|Recurrent Adult Grade III Lymphomatoid Granulomatosis\|Recurrent Adult Immunoblastic Large Cell Lymphoma\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Recurrent Childhood Anaplastic Large Cell Lymphoma\|Recurrent Childhood Grade III Lymphomatoid Granulomatosis\|Recurrent Childhood Large Cell Lymphoma\|Recurrent Childhood Lymphoblastic Lymphoma\|Recurrent Childhood Small Noncleaved Cell Lymphoma\|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Grade 3 Follicular Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Mycosis Fungoides+Sezary Syndrome\|Recurrent Small Lymphocytic Lymphoma\|Refractory Chronic Lymphocytic Leukemia\|Relapsing Chronic Myelogenous Leukemia\|Secondary Acute Myeloid Leukemia\|Secondary Myelodysplastic Syndromes\|Secondary Myelofibrosis\|Splenic Marginal Zone Lymphoma\|Stage I Chronic Lymphocytic Leukemia\|Stage II Chronic Lymphocytic Leukemia\|Stage III Chronic Lymphocytic Leukemia\|Stage IV Chronic Lymphocytic Leukemia\|T-cell Adult Acute Lymphoblastic Leukemia\|T-cell Childhood Acute Lymphoblastic Leukemia\|T-cell Large Granular Lymphocyte Leukemia\|Waldenstrom Macroglobulinemia	September 2007	Phase 2
NCT00006184	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Multiple Myeloma	February 8, 2001	Phase 2
NCT00005113	Boston Children´s Hospital	End-Stage Renal Disease\|Kidney Transplantation	July 1999	Phase 3
NCT00008021	University of California, Davis\|National Cancer Institute (NCI)	Lymphoma	February 2001	Phase 1
NCT00171496	Novartis	Kidney Transplant	October 2003	Phase 4
NCT00036738	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Adult Acute Lymphoblastic Leukemia in Remission\|Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1\|Blastic Phase\|Childhood Acute Lymphoblastic Leukemia in Remission\|Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1\|Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Chronic Phase of Disease\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Disease	July 13, 2001	Phase 2
NCT03419910	Bristol-Myers Squibb	Psoriasis	March 5, 2018	Phase 1
NCT00251004	Novartis	Kidney Transplantation\|Graft Rejection	October 2005	Phase 3
NCT00461825	Poitiers University Hospital	Kidney Transplantation	July 1998	Phase 3
NCT00123331	Heidelberg University\|Wyeth is now a wholly owned subsidiary of Pfizer	Heart Transplantation\|Renal Failure	October 2003	Phase 4
NCT00044954	University of Texas Southwestern Medical Center	Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases	November 1999	Phase 2
NCT00741338	Genzyme, a Sanofi Company\|BioMarin+Genzyme LLC\|Sanofi	Mucopolysaccharidosis I	September 2008	Phase 1\|Phase 2
NCT05573230	Eli Lilly and Company	Healthy	October 17, 2022	Phase 1
NCT00991458	Allergan	Laser In Situ Keratomileusis	October 2009	Phase 2
NCT00281983	German CLL Study Group	Chronic Lymphocytic Leukemia	June 2000	Phase 1\|Phase 2
NCT00303719	Masonic Cancer Center, University of Minnesota	Kidney Cancer\|Leukemia\|Lymphoma\|Multiple Myeloma\|Plasma Cell Neoplasm\|Myelodysplastic Syndromes	March 26, 2002	Phase 2
NCT01149759	Rockefeller University	Atopic Dermatitis\|Eczema	June 2010	Not Applicable
NCT00055653	Roswell Park Cancer Institute\|National Heart, Lung, and Blood Institute (NHLBI)	Leukemia\|Lymphoma\|Myelodysplastic Syndromes\|Myelodysplastic-Myeloproliferative Diseases	January 2003	Phase 2
NCT00001749	National Heart, Lung, and Blood Institute (NHLBI)\|National Institutes of Health Clinical Center (CC)	Fanconi´s Anemia\|Hematologic Disease	July 1998	Phase 2
NCT00919776	London School of Hygiene and Tropical Medicine\|Homes and Hospitals of St Giles\|Alert Hospital, Ethiopia\|Armauer Hansen Research Institute, Ethiopia	Leprosy	August 2010	Phase 2
NCT00376519	Masonic Cancer Center, University of Minnesota	Graft Versus Host Disease\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Secondary Myelofibrosis	May 2007	Phase 1
NCT01768312	Hanlim Pharm. Co., Ltd.	Dry Eye Syndromes	August 23, 2012	Phase 3
NCT00740467	Institut Paoli-Calmettes\|National Cancer Institute (NCI)	Graft Versus Host Disease\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Precancerous Condition	January 2008	Phase 2
NCT00525681	University of Oslo School of Pharmacy	Renal Transplantation	September 2007	Phase 4
NCT00571662	University of Nebraska\|Astex Pharmaceuticals, Inc.	Acute Myelogenous Leukemia\|Acute Lymphocytic Leukemia\|Chronic Myelogenous Leukemia\|Chronic Lymphocytic Leukemia\|Myelodysplastic Syndromes\|Multiple Myeloma\|Non-Hodgkins Lymphoma\|Hodgkins Disease\|Peripheral T-cell Lymphoma	December 2000	Phase 2
NCT00027547	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Leukemia	July 2001	Phase 1\|Phase 2
NCT04470804	Bing Han\|Peking Union Medical College Hospital	Pure Red Cell Aplasia, Acquired	August 1, 2020	Phase 4
NCT00343798	Fred Hutchinson Cancer Center\|National Heart, Lung, and Blood Institute (NHLBI)\|National Cancer Institute (NCI)\|Damon Runyon Cancer Research Foundation	Accelerated Phase Chronic Myelogenous Leukemia\|Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome\|Adult Acute Lymphoblastic Leukemia in Remission\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Adult Nasal Type Extranodal NK+T-cell Lymphoma\|Anaplastic Large Cell Lymphoma\|Childhood Acute Lymphoblastic Leukemia in Remission\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Burkitt Lymphoma\|Childhood Chronic Myelogenous Leukemia\|Childhood Diffuse Large Cell Lymphoma\|Childhood Immunoblastic Large Cell Lymphoma\|Childhood Myelodysplastic Syndromes\|Childhood Nasal Type Extranodal NK+T-cell Lymphoma\|Chronic Phase Chronic Myelogenous Leukemia\|Contiguous Stage II Adult Burkitt Lymphoma\|Contiguous Stage II Adult Diffuse Large Cell Lymphoma\|Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma\|Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma\|Contiguous Stage II Adult Lymphoblastic Lymphoma\|Contiguous Stage II Grade 3 Follicular Lymphoma\|Contiguous Stage II Mantle Cell Lymphoma\|de Novo Myelodysplastic Syndromes\|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue\|Nodal Marginal Zone B-cell Lymphoma\|Noncontiguous Stage II Adult Burkitt Lymphoma\|Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma\|Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma\|Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma\|Noncontiguous Stage II Adult Lymphoblastic Lymphoma\|Noncontiguous Stage II Grade 3 Follicular Lymphoma\|Noncontiguous Stage II Mantle Cell Lymphoma\|Previously Treated Myelodysplastic Syndromes\|Prolymphocytic Leukemia\|Recurrent Adult Burkitt Lymphoma\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent Adult Diffuse Mixed Cell Lymphoma\|Recurrent Adult Grade III Lymphomatoid Granulomatosis\|Recurrent Adult Immunoblastic Large Cell Lymphoma\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Childhood Anaplastic Large Cell Lymphoma\|Recurrent Childhood Grade III Lymphomatoid Granulomatosis\|Recurrent Childhood Large Cell Lymphoma\|Recurrent Childhood Lymphoblastic Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Grade 3 Follicular Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Small Lymphocytic Lymphoma\|Refractory Anemia\|Refractory Anemia With Excess Blasts\|Refractory Anemia With Excess Blasts in Transformation\|Refractory Chronic Lymphocytic Leukemia\|Refractory Multiple Myeloma\|Secondary Acute Myeloid Leukemia\|Secondary Myelodysplastic Syndromes\|Splenic Marginal Zone Lymphoma\|Stage I Adult Burkitt Lymphoma\|Stage I Adult Diffuse Large Cell Lymphoma\|Stage I Adult Diffuse Mixed Cell Lymphoma\|Stage I Adult Immunoblastic Large Cell Lymphoma\|Stage I Adult Lymphoblastic Lymphoma\|Stage I Childhood Lymphoblastic Lymphoma\|Stage I Grade 3 Follicular Lymphoma\|Stage I Mantle Cell Lymphoma\|Stage II Childhood Lymphoblastic Lymphoma\|Stage III Adult Burkitt Lymphoma\|Stage III Adult Diffuse Large Cell Lymphoma\|Stage III Adult Diffuse Mixed Cell Lymphoma\|Stage III Adult Immunoblastic Large Cell Lymphoma\|Stage III Adult Lymphoblastic Lymphoma\|Stage III Childhood Lymphoblastic Lymphoma\|Stage III Grade 3 Follicular Lymphoma\|Stage III Mantle Cell Lymphoma\|Stage IV Adult Burkitt Lymphoma\|Stage IV Adult Diffuse Large Cell Lymphoma\|Stage IV Adult Diffuse Mixed Cell Lymphoma\|Stage IV Adult Immunoblastic Large Cell Lymphoma\|Stage IV Adult Lymphoblastic Lymphoma\|Stage IV Childhood Lymphoblastic Lymphoma\|Stage IV Grade 3 Follicular Lymphoma\|Stage IV Mantle Cell Lymphoma	April 2006	Phase 1
NCT02554981	Allergan	Dry Eye Syndromes	July 21, 2015	Phase 4
NCT00003625	Children´s Oncology Group\|National Cancer Institute (NCI)	Brain Tumors\|Central Nervous System Tumors	December 1998	Phase 1
NCT02745717	Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine\|Ruijin Hospital\|Xinhua Hospital, Shanghai Jiao Tong University School of Medicine\|Shanghai Tongji Hospital, Tongji University School of Medicine\|Zhejiang Provincial Hospital of TCM	Severe Aplastic Anemia	January 2016	Phase 4
NCT00085449	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Neoplasms	May 2006	Phase 1\|Phase 2
NCT00093587	Jonsson Comprehensive Cancer Center\|National Cancer Institute (NCI)	Graft Versus Host Disease\|Leukemia	August 2004	Not Applicable
NCT00087581	Hoffmann-La Roche	Kidney Transplantation	June 2004	Phase 4
NCT00049634	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Leukemia\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases	January 2002	Phase 1\|Phase 2
NCT00150085	Novartis	Tacrolimus-associated Abnormal Glucose Metabolism in Kidney and Liver Transplant Recipients	February 2004	Phase 4
NCT00143806	University of Medicine and Dentistry of New Jersey\|Biogen\|Rutgers, The State University of New Jersey	Psoriasis	October 2003	Phase 2
NCT00003920	University of California, Davis\|National Cancer Institute (NCI)	Breast Cancer	April 1996	Phase 1
NCT00171743	Novartis	Liver Transplant	April 2004	Phase 4
NCT00232076	Novartis Pharmaceuticals\|Novartis	Severe Atopic Dermatitis	May 2004	Phase 3
NCT02887807	Hospices Civils de Lyon	Shockable Out of Hospital Cardiac Arrest	January 2017	Phase 3
NCT00002831	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Leukemia	August 1, 1995	Phase 1\|Phase 2
NCT00488436	PETHEMA Foundation	Myelodysplastic Syndrome	May 2002	Phase 4
NCT01693393	Charite University, Berlin, Germany	Sjögren´s Syndrome	March 2010	Phase 2
NCT00938236	APT Pharmaceuticals, Inc.	Lung Transplant	December 2009	Phase 3
NCT04849299	Atea Pharmaceuticals, Inc.\|Hoffmann-La Roche	Healthy Volunteer Study	April 18, 2021	Phase 1
NCT03750383	Enanta Pharmaceuticals, Inc\|Pharmaceutical Research Associates	RSV Infection	November 2, 2018	Phase 1
NCT00112645	Milton S. Hershey Medical Center\|National Cancer Institute (NCI)	Neuroblastoma\|Sarcoma\|Unspecified Childhood Solid Tumor, Protocol Specific	April 2005	Phase 1
NCT02188264	National Cancer Institute (NCI)	Recurrent Colorectal Carcinoma\|Solid Neoplasm\|Stage IIIA Colorectal Cancer AJCC v7\|Stage IIIB Colorectal Cancer AJCC v7\|Stage IIIC Colorectal Cancer AJCC v7\|Stage IVA Colorectal Cancer AJCC v7\|Stage IVB Colorectal Cancer AJCC v7	August 5, 2014	Phase 1
NCT00534430	City of Hope Medical Center\|National Cancer Institute (NCI)	Leukemia\|Myelodysplastic Syndromes	February 29, 2000	Phase 2
NCT05381766	NYU Langone Health	Diet Habit	June 1, 2022	Not Applicable
NCT00002789	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Leukemia	May 1996	Phase 3
NCT04530487	M.D. Anderson Cancer Center	Desmoplastic Small Round Cell Tumor\|Ewing Sarcoma+Peripheral Primitive Neuroectodermal Tumor\|Recurrent Desmoplastic Small Round Cell Tumor\|Recurrent Malignant Peripheral Nerve Sheath Tumor\|Recurrent Malignant Solid Neoplasm\|Recurrent Neuroblastoma\|Recurrent Rhabdomyosarcoma\|Refractory Desmoplastic Small Round Cell Tumor\|Refractory Malignant Peripheral Nerve Sheath Tumor\|Refractory Malignant Solid Neoplasm\|Refractory Neuroblastoma\|Refractory Rhabdomyosarcoma	August 19, 2020	Phase 2
NCT00860496	Pfizer	Healthy Volunteers	June 2009	Phase 1
NCT00796068	Fred Hutchinson Cancer Center	Acute Biphenotypic Leukemia\|Acute Lymphoblastic Leukemia in Remission\|Acute Myeloid Leukemia in Remission\|Blasts Under 5 Percent of Bone Marrow Nucleated Cells\|Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Myelodysplastic Syndrome	October 29, 2008	Phase 2
NCT01789255	National Cancer Institute (NCI)	Accelerated Phase Chronic Myelogenous Leukemia\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Adult Grade III Lymphomatoid Granulomatosis\|B-cell Chronic Lymphocytic Leukemia\|Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Chronic Myelomonocytic Leukemia\|Chronic Phase Chronic Myelogenous Leukemia\|Contiguous Stage II Adult Burkitt Lymphoma\|Contiguous Stage II Adult Diffuse Large Cell Lymphoma\|Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma\|Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma\|Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma\|Contiguous Stage II Adult Lymphoblastic Lymphoma\|Contiguous Stage II Grade 1 Follicular Lymphoma\|Contiguous Stage II Grade 2 Follicular Lymphoma\|Contiguous Stage II Grade 3 Follicular Lymphoma\|Contiguous Stage II Mantle Cell Lymphoma\|Contiguous Stage II Marginal Zone Lymphoma\|Contiguous Stage II Small Lymphocytic Lymphoma\|Cutaneous B-cell Non-Hodgkin Lymphoma\|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue\|Graft Versus Host Disease\|Intraocular Lymphoma\|Myelodysplastic Syndrome With Isolated Del(5q)\|Myelodysplastic+Myeloproliferative Neoplasm, Unclassifiable\|Nodal Marginal Zone B-cell Lymphoma\|Noncontiguous Stage II Adult Burkitt Lymphoma\|Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma\|Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma\|Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma\|Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma\|Noncontiguous Stage II Adult Lymphoblastic Lymphoma\|Noncontiguous Stage II Grade 1 Follicular Lymphoma\|Noncontiguous Stage II Grade 2 Follicular Lymphoma\|Noncontiguous Stage II Grade 3 Follicular Lymphoma\|Noncontiguous Stage II Mantle Cell Lymphoma\|Noncontiguous Stage II Marginal Zone Lymphoma\|Noncontiguous Stage II Small Lymphocytic Lymphoma\|Post-transplant Lymphoproliferative Disorder\|Primary Central Nervous System Hodgkin Lymphoma\|Primary Central Nervous System Non-Hodgkin Lymphoma\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Adult Burkitt Lymphoma\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent Adult Diffuse Mixed Cell Lymphoma\|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma\|Recurrent Adult Grade III Lymphomatoid Granulomatosis\|Recurrent Adult Hodgkin Lymphoma\|Recurrent Adult Immunoblastic Large Cell Lymphoma\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Grade 3 Follicular Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Small Lymphocytic Lymphoma\|Refractory Anemia\|Refractory Anemia With Excess Blasts\|Refractory Anemia With Ringed Sideroblasts\|Refractory Chronic Lymphocytic Leukemia\|Refractory Cytopenia With Multilineage Dysplasia\|Refractory Hairy Cell Leukemia\|Relapsing Chronic Myelogenous Leukemia\|Secondary Central Nervous System Hodgkin Lymphoma\|Secondary Central Nervous System Non-Hodgkin Lymphoma\|Small Intestine Lymphoma\|Splenic Marginal Zone Lymphoma\|Stage I Adult Burkitt Lymphoma\|Stage I Adult Diffuse Large Cell Lymphoma\|Stage I Adult Diffuse Mixed Cell Lymphoma\|Stage I Adult Diffuse Small Cleaved Cell Lymphoma\|Stage I Adult Hodgkin Lymphoma\|Stage I Adult Immunoblastic Large Cell Lymphoma\|Stage I Adult Lymphoblastic Lymphoma\|Stage I Chronic Lymphocytic Leukemia\|Stage I Grade 1 Follicular Lymphoma\|Stage I Grade 2 Follicular Lymphoma\|Stage I Grade 3 Follicular Lymphoma\|Stage I Mantle Cell Lymphoma\|Stage I Marginal Zone Lymphoma\|Stage I Small Lymphocytic Lymphoma\|Stage II Adult Hodgkin Lymphoma\|Stage II Chronic Lymphocytic Leukemia\|Stage III Adult Burkitt Lymphoma\|Stage III Adult Diffuse Large Cell Lymphoma\|Stage III Adult Diffuse Mixed Cell Lymphoma\|Stage III Adult Diffuse Small Cleaved Cell Lymphoma\|Stage III Adult Hodgkin Lymphoma\|Stage III Adult Immunoblastic Large Cell Lymphoma\|Stage III Adult Lymphoblastic Lymphoma\|Stage III Chronic Lymphocytic Leukemia\|Stage III Grade 1 Follicular Lymphoma\|Stage III Grade 2 Follicular Lymphoma\|Stage III Grade 3 Follicular Lymphoma\|Stage III Mantle Cell Lymphoma\|Stage III Marginal Zone Lymphoma\|Stage IV Adult Burkitt Lymphoma\|Stage IV Adult Diffuse Large Cell Lymphoma\|Stage IV Adult Diffuse Mixed Cell Lymphoma\|Stage IV Adult Diffuse Small Cleaved Cell Lymphoma\|Stage IV Adult Hodgkin Lymphoma\|Stage IV Adult Immunoblastic Large Cell Lymphoma\|Stage IV Adult Lymphoblastic Lymphoma\|Stage IV Chronic Lymphocytic Leukemia\|Stage IV Grade 1 Follicular Lymphoma\|Stage IV Grade 2 Follicular Lymphoma\|Stage IV Grade 3 Follicular Lymphoma\|Stage IV Mantle Cell Lymphoma\|Stage IV Marginal Zone Lymphoma\|Stage IV Small Lymphocytic Lymphoma\|Testicular Lymphoma\|Waldenström Macroglobulinemia	June 2013	Phase 2
NCT02314312	Mahidol University	Transplantation of Kidney\|Expanded Criteria Donor\|ECD	January 2012	Phase 3
NCT00031070	National Institute of Allergy and Infectious Diseases (NIAID)	HIV Infections		Phase 2
NCT03791827	Xiqiang Dang\|The Children´s Hospital Affiliated to Suzhou University\|Shandong Provincial Hospital\|Guizhou Provincial People´s Hospital\|LanZhou University\|The First Affiliated Hospital of Inner Mongolia Medical College\|People´s Hospital of Zhangjiajie\|Puyang Oilfield General Hospital\|The First Affiliated Hospital of Anhui Medical University\|Guizhou Maternal and Child Health Care Hospital\|The Second Affiliated Hospital & Yuying Children´s Hospital of Wenzhou Medical University\|Shenzhen Children´s Hospital\|The Second Affiliated Hospital of Harbin Medical University\|Yichang Central People´s Hospital\|Xian Children´s Hospital\|Wuhan Children´s Hospital, Tongji Medical College, Huazhong University of Science & Technology\|The First People´s Hospital of Yunnan\|The First Affiliated Hospital of Xiamen University\|The First Affiliated Hospital of Xinxiang Medical College\|Shanxi Provincial Maternity and Children´s Hospital\|Liaocheng People´s Hospital\|Fujian Provincial Hospital\|First Affiliated Hospital of Guangxi Medical University\|Second Hospital of Lanzhou University\|Guangzhou First People´s Hospital\|The Second Hospital of Shandong University\|Children´s Hospital of Hebei Province\|Beijing Children´s Hospital\|Zhengzhou Children´s Hospital\|The Children´s Hospital of Chongqing Medical University\|Wuxi Children´s Hospital\|The Children´s Hospital of Fudan University\|Shanghai Children´s Medical Center\|Qilu Children´s Hospital of Shandong University\|Second Xiangya Hospital of Central South University	Lupus Nephritis\|Children\|Steroid\|Immunosuppressive Treatment	December 1, 2018
NCT01954784	Case Comprehensive Cancer Center\|National Cancer Institute (NCI)	Refractory Multiple Myeloma\|Stage I Multiple Myeloma\|Stage II Multiple Myeloma\|Stage III Multiple Myeloma	October 7, 2013	Phase 1
NCT00425724	Oulu University Hospital	Purpura, Schoenlein-Henoch	January 2000	Phase 4
NCT01346397	Russian Academy of Medical Sciences\|Russian Scientific Center of Surgery	Acute Graft Rejection\|Chronic Allograft Nephropathy\|Polyomavirus-related Transplant Nephropathy	April 2009
NCT00520130	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Myelodysplastic Syndrome\|Hodgkin´s Lymphoma\|Non-Hodgkin´s Disease\|Acute Leukemia\|Multiple Myeloma	October 30, 2007	Phase 1\|Phase 2
NCT00001839	National Institutes of Health Clinical Center (CC)	Hematologic Diseases\|Myelodysplastic Syndromes	December 1998	Phase 2
NCT01469884	Irmandade Santa Casa de Misericórdia de Porto Alegre\|Novartis	Renal Allograft\|Hepatitis C	November 2011	Phase 4
NCT00653276	Organon and Co\|Schering-Plough	Cholesterol	November 2003	Phase 1
NCT02366585	PerioC Limited	Periodontitis	March 2015	Phase 2
NCT03277040	University of Pennsylvania	Diet Habit\|Obesity\|Food Habits	September 26, 2017	Not Applicable
NCT00493194	University Hospital, Antwerp\|Wyeth is now a wholly owned subsidiary of Pfizer\|Hoffmann-La Roche	Kidney Failure, Chronic\|Transplantation\|Immunosuppression\|Interstitial Fibrosis	May 2005	Phase 4
NCT00988715	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Chronic Myelomonocytic Leukemia\|Myelodysplastic+Myeloproliferative Neoplasm, Unclassifiable\|Previously Treated Myelodysplastic Syndrome\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Refractory Anemia With Excess Blasts\|Refractory Cytopenia With Multilineage Dysplasia\|Refractory Cytopenia With Multilineage Dysplasia and Ringed Sideroblasts\|Secondary Acute Myeloid Leukemia	April 21, 2010	Phase 1
NCT00086346	Wyeth is now a wholly owned subsidiary of Pfizer	Liver Transplantation	December 2002	Phase 3
NCT00404482	St. Franziskus Hospital	Uveitis\|Juvenile Idiopathic Arthritis	January 1991
NCT00008177	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Chronic Myelomonocytic Leukemia\|de Novo Myelodysplastic Syndromes\|Previously Treated Myelodysplastic Syndromes\|Recurrent Adult Acute Myeloid Leukemia\|Refractory Anemia With Excess Blasts\|Refractory Anemia With Excess Blasts in Transformation\|Refractory Anemia With Ringed Sideroblasts\|Refractory Cytopenia With Multilineage Dysplasia\|Secondary Myelodysplastic Syndromes\|Untreated Adult Acute Myeloid Leukemia	July 27, 1999	Phase 1
NCT00070174	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	December 2003	Phase 2
NCT02225756	Assistance Publique - Hôpitaux de Paris	Abdominal Aortic Aneurysm,\|Small Abdominal Aortic Aneurysm	December 2013	Phase 2
NCT04039347	Zambon SpA	Bronchiolitis Obliterans\|Obliterative Bronchiolitis\|Bronchiolitis Obliterans Syndrome	March 12, 2020	Phase 3
NCT00549289	Sirion Therapeutics, Inc.	Dry Eye Syndromes		Phase 3
NCT00412360	Medical College of Wisconsin\|National Heart, Lung, and Blood Institute (NHLBI)\|Blood and Marrow Transplant Clinical Trials Network\|National Cancer Institute (NCI)\|National Marrow Donor Program	Acute Myelogenous Leukemia\|Acute Lymphocytic Leukemia\|Chronic Myelogenous Leukemia\|Myelodysplastic Syndrome\|Natural Killer Cell Lymphoblastic Leukemia+Lymphoma	December 2006	Phase 3
NCT05057468	Assiut University	Primary Autoimmune Hemolytic Anemia	October 20, 2021	Phase 3
NCT01251575	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Adult Acute Lymphoblastic Leukemia\|Adult Acute Myeloid Leukemia\|Adult Diffuse Large B-Cell Lymphoma\|Adult Myelodysplastic Syndrome\|Adult Non-Hodgkin Lymphoma\|Aggressive Non-Hodgkin Lymphoma\|Childhood Acute Lymphoblastic Leukemia\|Childhood Acute Myeloid Leukemia\|Childhood Diffuse Large B-Cell Lymphoma\|Childhood Myelodysplastic Syndrome\|Childhood Non-Hodgkin Lymphoma\|Chronic Lymphocytic Leukemia\|Chronic Lymphocytic Leukemia in Remission\|Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Hematopoietic and Lymphoid Cell Neoplasm\|Mantle Cell Lymphoma\|Plasma Cell Myeloma\|Prolymphocytic Leukemia\|Recurrent Chronic Lymphocytic Leukemia\|Refractory Chronic Lymphocytic Leukemia\|T-Cell Prolymphocytic Leukemia\|Waldenstrom Macroglobulinemia\|Recurrent Diffuse Large B-Cell Lymphoma\|Recurrent Hodgkin Lymphoma	December 1, 2010	Phase 2
NCT00337493	Hoffmann-La Roche	Kidney Transplantation	December 2005	Phase 4
NCT05155007	Janssen Research & Development, LLC	Healthy	December 10, 2021	Phase 1
NCT01938625	Janssen R&D Ireland	Hepatitis C, Chronic	December 12, 2013	Phase 2
NCT00260208	Novartis Pharmaceuticals\|Novartis	Liver Transplant\|Hepatitis C	January 2006	Phase 4
NCT01820572	Bristol-Myers Squibb	Kidney Transplantation	March 27, 2013	Phase 3
NCT00006056	Fairview University Medical Center\|Office of Rare Diseases (ORD)	Chediak-Higashi Syndrome\|Graft Versus Host Disease\|X-Linked Lymphoproliferative Syndrome\|Familial Erythrophagocytic Lymphohistiocytosis\|Hemophagocytic Lymphohistiocytosis\|Virus-Associated Hemophagocytic Syndrome	March 2000	Not Applicable
NCT00002761	Columbia University	Leukemia	February 1996	Phase 1\|Phase 2
NCT04979884	Alexandria University\|Science and Technology Development Fund (STDF), ,Egypt	COVID-19 Acute Respiratory Distress Syndrome\|Cytokine Release Syndrome\|Pulmonary Fibrosis	August 1, 2021	Phase 3
NCT00609739	Masonic Cancer Center, University of Minnesota	Leukemia	June 1999	Phase 1\|Phase 2
NCT00001965	National Heart, Lung, and Blood Institute (NHLBI)\|National Institutes of Health Clinical Center (CC)	Cardiomyopathy, Hypertrophic\|Heart Hypertrophy	December 1999	Phase 2
NCT02498977	King´s College London\|King´s College Hospital NHS Trust\|National Institute for Health Research, United Kingdom	Transplantation, Liver	October 2015	Phase 4
NCT01595958	Hospices Civils de Lyon	Non Shockable Out of Hospital Cardiac Arrest	June 2010	Phase 3
NCT00035555	Bristol-Myers Squibb	Graft Rejection\|Kidney Transplantation\|Renal Transplantation	March 2001	Phase 2
NCT02424968	Robert Lowsky\|National Cancer Institute (NCI)\|Stanford University	Acute Myeloid Leukemia\|B-Cell Non-Hodgkin Lymphoma\|Chronic Lymphocytic Leukemia\|Hodgkin Lymphoma\|Myelodysplastic Syndrome\|Myeloproliferative Neoplasm\|T-Cell Non-Hodgkin Lymphoma	June 2015	Phase 2
NCT02416388	University Hospital, Angers	Acute Myeloid Leukemia (AML)	January 2015	Phase 2\|Phase 3
NCT00884585	Allergan	Atopic Conjunctivitis	May 2009	Phase 3
NCT01962636	Masonic Cancer Center, University of Minnesota	Acute Myeloid Leukemia (AML)\|Acute Lymphocytic Leukemia (ALL)\|Chronic Myelogenous Leukemia\|Plasma Cell Leukemia\|Myelofibrosis\|Myelodysplasia\|Chronic Lymphocytic Leukemia\|Small Lymphocytic Lymphoma\|Marginal Zone B-Cell Lymphoma\|Follicular Lymphoma\|Lymphoplasmacytic Lymphoma\|Mantle-Cell Lymphoma\|Prolymphocytic Leukemia\|Diffuse Large B Cell Lymphoma\|Lymphoblastic Lymphoma\|Burkitt´s Lymphoma\|Non-Hodgkin Lymphoma\|Multiple Myeloma	December 2016	Not Applicable
NCT01427881	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Accelerated Phase Chronic Myelogenous Leukemia\|Adult Acute Lymphoblastic Leukemia in Remission\|Adult Acute Megakaryoblastic Leukemia (M7)\|Adult Acute Myeloid Leukemia in Remission\|Adult Erythroleukemia (M6a)\|Adult Nasal Type Extranodal NK+T-cell Lymphoma\|Adult Pure Erythroid Leukemia (M6b)\|Anaplastic Large Cell Lymphoma\|Angioimmunoblastic T-cell Lymphoma\|Blastic Phase Chronic Myelogenous Leukemia\|Childhood Acute Erythroleukemia (M6)\|Childhood Acute Lymphoblastic Leukemia in Remission\|Childhood Acute Megakaryocytic Leukemia (M7)\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Burkitt Lymphoma\|Childhood Chronic Myelogenous Leukemia\|Childhood Diffuse Large Cell Lymphoma\|Childhood Immunoblastic Large Cell Lymphoma\|Childhood Myelodysplastic Syndromes\|Childhood Nasal Type Extranodal NK+T-cell Lymphoma\|Chronic Myelomonocytic Leukemia\|Chronic Phase Chronic Myelogenous Leukemia\|Cutaneous B-cell Non-Hodgkin Lymphoma\|de Novo Myelodysplastic Syndromes\|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue\|Hepatosplenic T-cell Lymphoma\|Intraocular Lymphoma\|Nodal Marginal Zone B-cell Lymphoma\|Noncutaneous Extranodal Lymphoma\|Peripheral T-cell Lymphoma\|Philadelphia Chromosome Negative Chronic Myelogenous Leukemia\|Post-transplant Lymphoproliferative Disorder\|Previously Treated Myelodysplastic Syndromes\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Adult Burkitt Lymphoma\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent Adult Diffuse Mixed Cell Lymphoma\|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma\|Recurrent Adult Grade III Lymphomatoid Granulomatosis\|Recurrent Adult Hodgkin Lymphoma\|Recurrent Adult Immunoblastic Large Cell Lymphoma\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Adult T-cell Leukemia+Lymphoma\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Recurrent Childhood Anaplastic Large Cell Lymphoma\|Recurrent Childhood Grade III Lymphomatoid Granulomatosis\|Recurrent Childhood Large Cell Lymphoma\|Recurrent Childhood Lymphoblastic Lymphoma\|Recurrent Childhood Small Noncleaved Cell Lymphoma\|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Grade 3 Follicular Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Mycosis Fungoides+Sezary Syndrome\|Recurrent Small Lymphocytic Lymphoma\|Recurrent+Refractory Childhood Hodgkin Lymphoma\|Relapsing Chronic Myelogenous Leukemia\|Secondary Acute Myeloid Leukemia\|Secondary Myelodysplastic Syndromes\|Small Intestine Lymphoma\|Splenic Marginal Zone Lymphoma\|Stage III Multiple Myeloma\|Testicular Lymphoma\|Waldenström Macroglobulinemia	September 2011	Phase 2
NCT00002456	Fred Hutchinson Cancer Center	Graft Versus Host Disease\|Leukemia\|Lymphoma	May 1986	Phase 3
NCT02496975	Edward Hall,PhD\|University of Kentucky	Traumatic Brain Injury	August 7, 2017	Phase 1\|Phase 2
NCT02226068	University of Aarhus	Atopic Dermatitis	June 2002	Not Applicable
NCT03656926	Zambon SpA	Bronchiolitis Obliterans\|Chronic Rejection of Lung Transplant\|Lung Transplant Rejection\|Lung Transplant; Complications\|Lung Transplant Failure and Rejection\|Chronic Lung Allograft Dysfunction	March 29, 2019	Phase 3
NCT00636909	Beth Israel Deaconess Medical Center\|Amgen	AML\|ALL\|CML Chronic Phase, Accelerated Phase, or Blast Crisis\|CLL\|MDS\|RELAPSED NON-HODGKIN´S OR HODGKIN´S LYMPHOMA\|APLASTIC ANEMIA\|MULTIPLE MYELOMA\|MYELOPROLIFERATIVE DISORDER (P Vera, CMML, ET)	July 1999	Phase 2
NCT00264355	University of Oslo School of Pharmacy	Heart Transplantation\|Acute Renal Failure	December 2005	Phase 4
NCT00080925	National Institutes of Health Clinical Center (CC)\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Neoplasms	February 2004	Phase 1
NCT00009776	University of California, Davis\|National Cancer Institute (NCI)	Lymphoma	March 2001	Phase 1
NCT00371826	Novartis Pharmaceuticals\|Novartis	Renal Transplanted Recipients	March 2006	Phase 4
NCT00354419	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Aplastic Anemia	February 2006	Phase 1
NCT00118742	Hoffmann-La Roche	Liver Transplantation	August 2005	Phase 4
NCT00378677	University Medical Center Groningen	Lung Transplantation\|Bronchiolitis Obliterans	February 2007	Early Phase 1
NCT01429844	Universitätsklinikum Hamburg-Eppendorf	Bronchiolitis Obliterans\|Immunosuppression	January 2001	Phase 3
NCT01129739	Shandong University\|National Natural Science Foundation of China	Myelodysplastic Syndromes	May 2010	Phase 2
NCT00905515	East Carolina University\|Astellas Pharma US, Inc.	Kidney Transplantation	August 2003	Phase 4
NCT00723099	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Acute Myeloid Leukemia\|Aggressive Non-Hodgkin Lymphoma\|Chronic Myelogenous Leukemia\|Chronic Phase Chronic Myelogenous Leukemia\|Indolent Non-Hodgkin Lymphoma\|Lymphoma\|Mixed Phenotype Acute Leukemia\|Myelodysplastic Syndrome\|Myeloproliferative Neoplasm\|Recurrent Chronic Lymphocytic Leukemia\|Recurrent Follicular Lymphoma\|Recurrent Lymphoplasmacytic Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Plasma Cell Myeloma\|Recurrent Small Lymphocytic Lymphoma\|Recurrent T-Cell Non-Hodgkin Lymphoma\|Refractory Chronic Lymphocytic Leukemia\|Refractory Chronic Myelogenous Leukemia\|Refractory Follicular Lymphoma\|Refractory Hodgkin Lymphoma\|Refractory Lymphoplasmacytic Lymphoma\|Refractory Mantle Cell Lymphoma\|Refractory Small Lymphocytic Lymphoma\|T-Cell Non-Hodgkin Lymphoma	June 25, 2008	Phase 2
NCT04734197	Surface Pharmaceuticals, Inc.	Dry Eye Disease	January 11, 2021	Phase 2
NCT00383448	Masonic Cancer Center, University of Minnesota	Adrenoleukodystrophy\|Metachromatic Leukodystrophy\|Globoid Cell Leukodystrophy\|Tay Sachs Disease\|Sandhoffs Disease\|Wolman Disease\|I-Cell Disease\|Sanfilippo Syndrome\|GM1 Gangliosidosis	September 2006	Phase 2
NCT00139035	University of Oslo School of Pharmacy	Chronic Renal Failure	April 2005	Phase 4
NCT00976300	Institute of Rheumatology, Prague\|Ministry of Health, Czech Republic\|Charles University, Czech Republic\|Palacky University\|Department of Rheumatology, Hospital, Ceske Budejovice, Czech Republic\|National Institute of Rheumatology, Piestany, Slovakia\|St. Anna Hospital, Brno, Czech	Systemic Lupus Erythematosus\|Lupus Nephritis	January 2002	Phase 2
NCT01299922	Hospital Universitario Fundación Alcorcón\|Hospital Universitario 12 de Octubre\|Hospital General Universitario Gregorio Marañon\|Hospital Universitario Ramon y Cajal\|Hospital Infanta Sofia\|Hospital Universitario Infanta Leonor\|Hospital Universitario Reina Sofia de Cordoba\|Hospital Regional Universitario Carlos Haya\|Hospital Universitario Virgen de la Victoria\|University Hospital of the Nuestra Señora de Candelaria\|Hospital Universitario de Guadalajara. Spain\|Hospital San Pedro de Alcantara\|Hospital Juan Canalejo	Lupus Nephritis	February 2011	Phase 3
NCT01038167	Vertex Pharmaceuticals Incorporated\|Tibotec Pharmaceutical Limited	Hepatitis C	January 2010	Phase 1
NCT00005935	National Heart, Lung, and Blood Institute (NHLBI)\|National Institutes of Health Clinical Center (CC)	Aplastic Anemia	June 2000	Phase 2
NCT02987257	Vanderbilt University Medical Center\|University of Ottawa\|University of Toronto	Stevens-Johnson Syndrome\|Toxic Epidermal Necrolyses	November 30, 2022	Phase 3
NCT00014508	Eastern Cooperative Oncology Group\|National Cancer Institute (NCI)	Multiple Myeloma and Plasma Cell Neoplasm	April 2001	Phase 2
NCT00317876	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Fanconi Anemia	June 1998	Phase 1

Appearance

Solid

Source

the fungus Beauveria nivea.

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 62.5 mg/mL ( 51.97 mM ; Need ultrasonic)

Ethanol : 50 mg/mL ( 41.58 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.8315 mL	4.1576 mL	8.3152 mL
5 mM	0.1663 mL	0.8315 mL	1.6630 mL
10 mM	0.0832 mL	0.4158 mL	0.8315 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: corn oil

Solubility: 20 mg/mL (16.63 mM); Clear solution; Need ultrasonic
2.

Add each solvent one by one: 5% DMSO >> 40% PEG300 >> 5% Tween-80 >> 50% saline

Solubility: 2.62 mg/mL (2.18 mM); Suspended solution; Need ultrasonic
3.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: 2.08 mg/mL (1.73 mM); Suspended solution; Need ultrasonic
4.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: 2.08 mg/mL (1.73 mM); Suspended solution; Need ultrasonic
5.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.08 mg/mL (1.73 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Handschumacher RE, et al. Cyclophilin: a specific cytosolic binding protein for cyclosporin A. Science. 1984 Nov 2;226(4674):544-7.
[2] Liu J, et al. Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell. 1991 Aug 23;66(4):807-15.
[3] Fruman DA, et al. Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A. Proc Natl Acad Sci U S A. 1992 May 1;89(9):3686-90.
[4] Flanagan WM, et al. Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A. Nature. 1991 Aug 29;352(6338):803-7.
[5] Nicolli A, et al. Interactions of cyclophilin with the mitochondrial inner membrane and regulation of the permeability transition pore, and cyclosporin A-sensitive channel. J Biol Chem. 1996 Jan 26;271(4):2185-92.
[6] Borel JF, et al. Effects of the new anti-lymphocytic peptide cyclosporin A in animals. Immunology. 1977 Jun;32(6):1017-25.
[7] Williams, R, et al. Randomised trial comparing FK506 and cyclosporin in prevention of liver allograft rejection. European FK506 Multicentre Liver Study Group. Lancet, 1994, 344(8920), 423-428.
[8] Dalmarco EM, et al. Cyclosporin A inhibits CD11a/CD18 adhesion molecules due to inhibition of TNFalpha and IL-1 beta levels in the mouse model of pleurisy induced by carrageenan. Cell Adh Migr. 2008 Oct-Dec;2(4):231-5.

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