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[CAS NO. 60-00-4] Ethylenediaminetetraacetic acid
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-Y0682 |
| Brand: | MCE |
| CAS: | 60-00-4 |
Overview
| MDL | MFCD00003541 |
|---|---|
| Molecular Weight | 292.24 |
| Molecular Formula | C10H16N2O8 |
| SMILES | O=C(O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O |
5 Publications Citing Use of MCE
Summary
Ethylenediaminetetraacetic acid (EDTA) is a metal chelators (binds to metal divalent and trivalent cations including calcium), which shows activities of anticoagulant and anti-hypercalcemic. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification . Ethylenediaminetetraacetic acid can also decrease the formation of disulfide bonds [1] [2] [3] .
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date | Phase |
|---|---|---|---|---|
| NCT03985371 | University of Rochester|Livionex Inc |
Corneal Dystrophy, Band-Shaped
|
June 29, 2020 | Early Phase 1 |
| NCT01118663 | Cumberland Pharmaceuticals |
Acetaminophen Overdose
|
September 2010 | Phase 3 |
| NCT00237952 | Chang Gung Memorial Hospital |
Diabetic Nephropathies|Diabetes Mellitus, Type II
|
August 2005 | Not Applicable |
| NCT03419429 | Ain Shams University |
Chronic Periodontitis
|
January 2016 | Phase 4 |
| NCT03336970 | Mehmet Kemal �al??kan|Ege University |
Root Canal Infection
|
January 1, 2011 | Not Applicable |
| NCT02733185 | Mt. Sinai Medical Center, Miami|National Center for Complementary and Integrative Health (NCCIH)|National Heart, Lung, and Blood Institute (NHLBI)|Duke Clinical Research Institute |
Diabetes|Myocardial Infarction
|
October 2016 | Phase 3 |
| NCT04786327 | Tanta University |
Periodontal Regeneration
|
January 1, 2018 | Phase 2 |
| NCT04559334 | Boston Children´s Hospital|SterileCare Inc. |
Central Line Complication|Central Line-associated Bloodstream Infection (CLABSI)
|
December 21, 2020 | Not Applicable |
| NCT00227409 | Chang Gung Memorial Hospital |
Urologic Disease
|
November 2001 | Not Applicable |
| NCT03424746 | Mt. Sinai Medical Center, Miami |
Critical Limb Ischemia|Peripheral Arterial Disease
|
August 2015 | Early Phase 1 |
| NCT05170932 | Ain Shams University |
Periodontal Bone Loss
|
January 2017 | Not Applicable |
| NCT02714075 | Swiss Federal Institute of Technology|University for Development Studies, Tamale, Ghana |
Iron Deficiency and+or Anemia
|
April 2016 | Not Applicable |
| NCT04154553 | University Hospital, Basel, Switzerland|Toppharm Apotheke Hersberger, Spalenberg 41, CH-4051 Basel |
Adverse Drug Reaction|Therapy Failure
|
October 15, 2019 | |
| NCT04548713 | Fraser Health|SterileCare Inc.|Center for Health Evaluation & Outcome Services |
Central Venous Catheter Thrombosis|Central Venous Catheter Related Bloodstream Infection|Catheter Complications|Catheter Blockage|Catheter Dysfunction|Central Line-associated Bloodstream Infection (CLABSI)|Catheter|Catheter Infection
|
March 22, 2022 | Not Applicable |
| NCT00044213 | Mt. Sinai Medical Center, Miami|National Heart, Lung, and Blood Institute (NHLBI)|National Center for Complementary and Integrative Health (NCCIH) |
Coronary Artery Disease
|
September 2003 | Phase 3 |
| NCT04893577 | University of Utah |
Herpes Simplex Oral
|
January 20, 2022 | Phase 2 |
| NCT04067245 | University Health Network, Toronto |
Catheter Complications
|
April 1, 2019 | Not Applicable |
| NCT01950975 | Centre Hospitalier Universitaire Dijon |
Malformations With Skin Manifestations Suggesting Mosaicism
|
Not Applicable | |
| NCT04310254 | Istanbul Medipol University Hospital |
Postoperative Pain|Endodontically Treated Teeth
|
September 1, 2019 | Not Applicable |
| NCT03253393 | The University of New South Wales|Menicon Co., Ltd. |
Optometry
|
June 4, 2018 | Not Applicable |
| NCT02286258 | Assistance Publique - Hôpitaux de Paris|Ministry of Health, France |
Renal Insufficiency, Chronic|Kidney Diseases
|
October 2014 | Phase 1|Phase 2 |
| NCT04980066 | Kafrelsheikh University |
Gingival Recession
|
August 3, 2021 | Not Applicable |
| NCT05064462 | Assistance Publique - Hôpitaux de Paris|BioMérieux |
Heart Transplant Rejection|Heart Transplant Infection|Virus
|
March 3, 2022 | |
| NCT03853200 | Dow University of Health Sciences |
Endodontic Disease|Root Canal Infection
|
April 3, 2017 | Phase 2|Phase 3 |
| NCT00757458 | University of Sao Paulo|AstraZeneca |
Drug Contamination
|
December 2008 | Not Applicable |
| NCT04044417 | Ain Shams University |
Periodontitis
|
August 25, 2016 | Phase 4 |
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
0.1 M NaOH : 6.67 mg/mL ( 22.82 mM ; ultrasonic and warming and adjust pH to 7 with NaOH and heat to 60°C)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 3.4218 mL | 17.1092 mL | 34.2185 mL |
| 5 mM | 0.6844 mL | 3.4218 mL | 6.8437 mL |
| 10 mM | 0.3422 mL | 1.7109 mL | 3.4218 mL |
References
- [1] Chumanov RS, et al. Artifact-inducing enrichment of ethylenediaminetetraacetic acid and ethyleneglycoltetraacetic acid on anion exchange resins. Anal Biochem. 2011 May 1;412(1):34-9.
- [2] Banfi G, et al. The role of ethylenediamine tetraacetic acid (EDTA) as in vitro anticoagulant for diagnostic purposes. Clin Chem Lab Med. 2007;45(5):565-76.
- [3] Ibad A, et al. Chelation therapy in the treatment of cardiovascular diseases. J Clin Lipidol. 2016 Jan-Feb;10(1):58-62.
Synonyms
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