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[CAS NO. 607-80-7] Sesamin
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-N0121 |
| Brand: | MCE |
| CAS: | 607-80-7 |
Overview
| MDL | MFCD00216134 |
|---|---|
| Molecular Weight | 354.35 |
| Molecular Formula | C20H18O6 |
| SMILES | [H][C@@]12[C@@H](C3=CC=C(OCO4)C4=C3)OC[C@]1([H])[C@@H](C5=CC=C(OCO6)C6=C5)OC2 |
1 Publications Citing Use of MCE
Summary
IC50 & Target
delta 5 desaturase [1]
In Vitro
Pretreated with sesamin, Excess generation of nitric oxide in lipopolysaccharide-stimulated rat primary microglia cells was significantly attenuated [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
Sesamin (o.p.; 20 mg/kg/day) significantly reduces the infarct size by approximately 50% in male gerbils (60-85 g) [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 100 mg/mL ( 282.21 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.8221 mL | 14.1103 mL | 28.2207 mL |
| 5 mM | 0.5644 mL | 2.8221 mL | 5.6441 mL |
| 10 mM | 0.2822 mL | 1.4110 mL | 2.8221 mL |
References
- [1] Cheng FC, et al. Neuroprotective effects of sesamin and sesamolin on gerbil brain in cerebral ischemia. Int J Biomed Sci. 2006 Sep;2(3):284-8.
- [2] Shimizu S, et al. Sesamin is a potent and specific inhibitor of delta 5 desaturase in polyunsaturated fatty acidbiosynthesis. Lipids. 1991 Jul;26(7):512-6.
Synonyms
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