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[CAS NO. 61422-45-5] Carmofur
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-B0182 |
| Brand: | MCE |
| CAS: | 61422-45-5 |
Overview
| MDL | MFCD00866284 |
|---|---|
| Molecular Weight | 257.26 |
| Molecular Formula | C11H16FN3O3 |
| SMILES | O=C(N(C(N1)=O)C=C(F)C1=O)NCCCCCC |
3 Publications Citing Use of MCE
Summary
Carmofur (HCFU), a derivative of 5-Fluorouracil, is an antineoplastic agent. Carmofur is an inhibitor of acid ceramidase with an IC 50 of 79 nM for the rat enzyme. Carmofur inhibits the SARS-CoV-2 main protease (Mpro). Carmofur Inhibits SARS-CoV-2 in Vero E6 cell with an EC 50 of 24.3 μM [1] [2] .
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : ≥ 100 mg/mL ( 388.71 mM )
H 2 O : 0.67 mg/mL ( 2.60 mM ; Need ultrasonic)
* "≥" means soluble, but saturation unknown.
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 3.8871 mL | 19.4356 mL | 38.8712 mL |
| 5 mM | 0.7774 mL | 3.8871 mL | 7.7742 mL |
| 10 mM | 0.3887 mL | 1.9436 mL | 3.8871 mL |
References
Synonyms
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