[CAS NO. 619331-12-3] BMS-585248
PRODUCTS SPECIFICATIONS [619331-12-3]
DESCRIPTION [619331-12-3]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 447.42 |
| Molecular Formula | C22H18FN7O3 |
| SMILES | O=C(N1CCN(C(C2=CC=CC=C2)=O)CC1)C(C3=CNC4=C3C(F)=CN=C4N5N=NC=C5)=O |
Summary
IC50 & Target
|
HIV-1 |
In Vivo
BMS-585248 (intravenous (1 mg/kg) and oral (5-200 mg/kg); once) has a good pharmacokinetic profile, with AUC values of 3220 nM·h and 8064 nM·h after IV (1 mg/kg) and oral (5 mg/kg) administration in male rats, respectively [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
| Animal Model: | Male rats [1] | ||||||||||||||||
| Dosage: | 5, 15, and 200 mg/kg | ||||||||||||||||
| Administration: | Orally, once (Pharmacokinetic Analysis) | ||||||||||||||||
| Result: |
Pharmacokinetic Parameters of BMS-585248 in male rats
[1]
.
|
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.