[CAS NO. 65052-63-3] Cefetamet

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PRODUCTS SPECIFICATIONS [65052-63-3]

Catalog

HY-A0111

Brand

MCE

CAS

65052-63-3

DESCRIPTION [65052-63-3]

Overview

MDL	-
Molecular Weight	397.43
Molecular Formula	C14H15N5O5S2
SMILES	O=C(C(N12)=C(C)CS[C@]2([H])[C@H](NC(/C(C3=CSC(N)=N3)=N\OC)=O)C1=O)O

For research use only. We do not sell to patients.

Summary

Cefetamet is a cephalosporin antibiotic . Cefetamet has the potential for the research of both upper and lower community-acquired respiratory tract infections ^[1] .

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 25 mg/mL ( 62.90 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.5162 mL	12.5808 mL	25.1617 mL
5 mM	0.5032 mL	2.5162 mL	5.0323 mL
10 mM	0.2516 mL	1.2581 mL	2.5162 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (6.29 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (6.29 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (6.29 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Bryson HM, et al. Cefetamet pivoxil. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs. 1993;45(4):589-621.

Synonyms

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-methyl-8-oxo-, (6R,7R)-

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-methyl-8-oxo-, [6R-[6α,7β(Z)]]-

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-methyl-8-oxo-, (6R,7R)-

(6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Cefetamet

Deacetoxycefotaxime

LY 97964

Ro 15-8074

FR 13300

Antibiotic Ro 15-8074

Ro 15-8074/005

Altamet

Cepime O

Ultipime O