[CAS NO. 661-19-8] 1-Docosanol
PRODUCTS SPECIFICATIONS [661-19-8]
DESCRIPTION [661-19-8]
Overview
| MDL | MFCD00002939 |
|---|---|
| Molecular Weight | 326.60 |
| Molecular Formula | C22H46O |
| SMILES | CCCCCCCCCCCCCCCCCCCCCCO |
Summary
1-Docosanol is a saturated fatty alcohol used traditionally as an emollient, emulsifier, and thickener in cosmetics, and nutritional supplement; inhibitor of lipid-enveloped viruses including herpes simplex.
Appearance
Solid
Source
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
Ethanol : 50 mg/mL ( 153.09 mM ; Need ultrasonic)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
H 2 O : < 0.1 mg/mL (insoluble)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 3.0618 mL | 15.3092 mL | 30.6185 mL |
| 5 mM | 0.6124 mL | 3.0618 mL | 6.1237 mL |
| 10 mM | 0.3062 mL | 1.5309 mL | 3.0618 mL |
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1.
Add each solvent one by one: 10% EtOH >> 90% corn oil
Solubility: ≥ 2.5 mg/mL (7.65 mM); Clear solution
References
- [1] Katz DH, et al. Antiviral activity of 1-docosanol, an inhibitor of lipid-enveloped viruses including herpes simplex. Proc Natl Acad Sci U S A. 1991 Dec 1;88(23):10825-9.
- [2] Sacks SL, et al. Clinical efficacy of topical docosanol 10% cream for herpes simplex labialis: A multicenter, randomized, placebo-controlled trial. J Am Acad Dermatol. 2001 Aug;45(2):222-30.
Synonyms