[CAS NO. 66532-85-2] Propacetamol
PRODUCTS SPECIFICATIONS [66532-85-2]
DESCRIPTION [66532-85-2]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 264.32 |
| Molecular Formula | C14H20N2O3 |
| SMILES | O=C(OC1=CC=C(NC(C)=O)C=C1)CN(CC)CC |
Summary
Propacetamol is an analgesic agent. Propacetamol also is a precursor form of paracetamol. Propacetamol can be used in postoperative pain, acute trauma and gastrointestinal disorders [1] .
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date | Phase |
|---|---|---|---|---|
| NCT03352362 | Yonsei University |
Inguinal Hernia
|
December 15, 2017 | Not Applicable |
| NCT02116257 | Yonsei University |
PONV|Propacetamol
|
November 2013 | Not Applicable |
| NCT02515188 | Yonsei University |
Arrhythmia
|
August 7, 2015 | Not Applicable |
| NCT03878082 | Mackay Memorial Hospital |
Uterine Pain
|
August 12, 2019 | Not Applicable |
| NCT02577068 | Yonsei University |
Thyroidectomy|Pain
|
November 15, 2015 | Not Applicable |
| NCT02355678 | Makassed General Hospital |
Postoperative Nausea and Vomiting
|
January 2015 | Not Applicable |
| NCT01833728 | Yonsei University |
Renal Tumor
|
April 2013 | Not Applicable |
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
H 2 O : 100 mg/mL ( 378.33 mM ; Need ultrasonic)
DMSO : 20.83 mg/mL ( 78.81 mM ; ultrasonic and warming and heat to 60°C)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 3.7833 mL | 18.9165 mL | 37.8329 mL |
| 5 mM | 0.7567 mL | 3.7833 mL | 7.5666 mL |
| 10 mM | 0.3783 mL | 1.8916 mL | 3.7833 mL |
-
1.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (378.33 mM); Clear solution; Need ultrasonic
-
2.
Add each solvent one by one: 10% DMSO >> 90% corn oil
Solubility: ≥ 2.5 mg/mL (9.46 mM); Clear solution
-
3.
-
4.
Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)
Solubility: ≥ 2.08 mg/mL (7.87 mM); Clear solution