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[CAS NO. 675104-49-1] DSHS00884
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-113794 |
| Brand: | MCE |
| CAS: | 675104-49-1 |
Overview
| MDL | - |
|---|---|
| Molecular Weight | 308.38 |
| Molecular Formula | C12H12N4O2S2 |
| SMILES | S=C1N(C(CSC2=CC=CC=C2[N+]([O-])=O)=NN1)CC=C |
1 Publications Citing Use of MCE
Summary
DSHS00884 is a potent human papillomavirus E6 inhibitor with an IC 50 of 10 μM [1] .
IC50 & Target
IC50: 10 μM (human papillomavirus E6) [1]
In Vitro
DSHS00884 stabilizes p53 levels in HPV-positive cells by blocking E6-mediated p53 degradation with an IC 50 of 2.5-25 μM [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 250 mg/mL ( 810.69 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 3.2428 mL | 16.2138 mL | 32.4275 mL |
| 5 mM | 0.6486 mL | 3.2428 mL | 6.4855 mL |
| 10 mM | 0.3243 mL | 1.6214 mL | 3.2428 mL |
-
1.
-
2.
Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)
Solubility: ≥ 2.08 mg/mL (6.74 mM); Clear solution
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