[CAS NO. 676129-92-3] DevalerylValsartanImpurity

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PRODUCTS SPECIFICATIONS [676129-92-3]

Catalog

HY-131280

Brand

MCE

CAS

676129-92-3

MDL	MFCD30342453
Molecular Weight	351.40
Molecular Formula	C19H21N5O2
SMILES	CC(C)[C@@H](C(O)=O)NCC1=CC=C(C2=CC=CC=C2C3=NNN=N3)C=C1

For research use only. We do not sell to patients.

Devaleryl Valsartan Impurity is an intermediate in the synthesis of Valsartan ^[1] .

Solid

Room temperature in continental US; may vary elsewhere.

In Vitro:

DMSO : 250 mg/mL ( 711.44 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.08 mg/mL (5.92 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.08 mg/mL (5.92 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.08 mg/mL (5.92 mM); Clear solution

* All of the co-solvents are available by MCE.