- Cart - 0 item(s)
- $0.00
Your shopping cart is empty!
- Chemistry
- Bioactive Molecules
- Anti-infection
- Apoptosis
- Autophagy
- Cell Cycle/DNA Damage
- Cytoskeleton
- Epigenetics
- GPCR/G Protein
- Immunology/Inflammation
- JAK/STAT Signaling
- MAPK/ERK Pathway
- Membrane Transporter/Ion Channel
- Metabolic Enzyme/Protease
- Neuronal Signaling
- NF-κB
- PI3K/Akt/mTOR
- PROTAC
- Protein Tyrosine Kinase/RTK
- Stem Cell/Wnt
- TGF-beta/Smad
- Vitamin D Related/Nuclear Receptor
- Others
- Methylation
- Cytoskeletal Signaling
- Natural Products
- Alkaloids
- Amino acid
- Anthraquinones
- Cerebrosides
- Chalcones
- Coumarins
- Diterpenoids
- Flavonoids
- Iridoids
- Lignans
- Lipids
- Miscellaneous
- Monoterpenoids
- Other terpenes
- Phenols
- Phenylpropanoids
- Quinones
- Saccharides
- Sesquiterpenoids
- Steroids
- Tetraterpenoids
- Thiophenes
- Triterpenoids
- Xanthones
- Polyphenols
- Stibene glucosides
- Oligose
- Anthocyanins
- Miscellaneous
- Chromones
- Terpenoids
- Indoles
- Procyanidins
- Aliphatics
- Botanical Cyclopeptides
- ADCs
- Antibodies
- Multiplex IHC
- Material Science
- Others
[CAS NO. 68729-05-5] ARM1
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-W027340 |
| Brand: | MCE |
| CAS: | 68729-05-5 |
Overview
| MDL | - |
|---|---|
| Molecular Weight | 266.36 |
| Molecular Formula | C16H14N2S |
| SMILES | NC1=NC(C(C=C2)=CC=C2CC3=CC=CC=C3)=CS1 |
Summary
ARM1 (4BSA) is a potent aminopeptidase and epoxide hydrolase inhibitor. ARM1 shows aminopeptidase inhibitory activity with an IC 50 7.61 µM and epoxide hydrolase inhibitory activity with an IC 50 12.4 µM [1] .
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date | Phase |
|---|---|---|---|---|
| NCT02356978 | Assistance Publique - Hôpitaux de Paris |
Crigler Najjar Syndrome|Children
|
December 2014 | Not Applicable |
| NCT03966131 | Hospices Civils de Lyon |
Toothless
|
September 2019 | Not Applicable |
| NCT01813994 | Yonsei University |
Early Gastric Cancer or Gastric Adenoma
|
November 2014 | Not Applicable |
| NCT02854202 | Hospital de Clinicas Caracas|Tel Aviv University |
Type 2 Diabetes
|
August 2012 | Not Applicable |
| NCT02748707 | Tata Memorial Hospital |
Oral Squamous Cell Carcinoma|Carcinoma of Buccal Mucosa|Tongue Cancers|Head and Neck Cancers
|
August 18, 2015 | Phase 2 |
| NCT04187105 | University of Illinois at Chicago |
Acute Leukemia|MDS
|
January 27, 2020 | Phase 2 |
| NCT04798638 | TYK Medicines, Inc |
Healthy Volunteers
|
April 30, 2021 | Phase 1 |
| NCT00202735 | Sorlandet Hospital HF|Oslo University Hospital|Haukeland University Hospital|Sykehuset i Vestfold HF|Helse Stavanger HF|Sykehuset Telemark|Sykehuset Buskerud HF|Blefjell Hospital HF|Sykehuset Asker og Baerum|St. Olavs Hospital|University Hospital, Akershus |
Shoulder Dislocation
|
January 2005 | Phase 2|Phase 3 |
| NCT04428086 | Jiangsu HengRui Medicine Co., Ltd. |
Solid Tumor, Adult
|
July 27, 2020 | Phase 1 |
| NCT03331575 | Shanghai Chest Hospital |
Unresectable Stage III Non-small-cell Lung Cancer
|
November 2017 | Phase 3 |
| NCT03185988 | Shen Lin|Peking University |
Targeted Therapy|HER2|Biliary Tract Cancer|Esophageal Squamous Cell Carcinoma|Colorectal Cancer
|
July 1, 2017 | Phase 2 |
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 250 mg/mL ( 938.58 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 3.7543 mL | 18.7716 mL | 37.5432 mL |
| 5 mM | 0.7509 mL | 3.7543 mL | 7.5086 mL |
| 10 mM | 0.3754 mL | 1.8772 mL | 3.7543 mL |
-
1.
Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)
Solubility: 2.08 mg/mL (7.81 mM); Suspended solution; Need ultrasonic
Arctom is a premier supply platform offering over 600K unique items of Building Blocks, Bioactive Molecules, Natural Products, ADC PEG Linkers, Antibodies, and other Research Chemicals for global pharmaceutical, biotech, university, and industrial customers. We accelerate your research by providing better and faster purchasing experience & services.