[CAS NO. 68892-41-1] 5'-O-DMT-N2-ibu-dG

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PRODUCTS SPECIFICATIONS [68892-41-1]

Catelog

HY-W010702

Brand

MCE

CAS

68892-41-1

DESCRIPTION [68892-41-1]

Overview

MDL	MFCD00010059
Molecular Weight	639.70
Molecular Formula	C35H37N5O7
SMILES	O[C@H]1C[C@H](N2C(N=C(NC(C(C)C)=O)NC3=O)=C3N=C2)O[C@@H]1COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6

For research use only. We do not sell to patients.

Summary

5'-O-DMT-N2-ibu-dG (N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine) is a deoxynucleoside which can be used in the preparation of oligonucleotides ^[1] .

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 156.32 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.5632 mL	7.8162 mL	15.6323 mL
5 mM	0.3126 mL	1.5632 mL	3.1265 mL
10 mM	0.1563 mL	0.7816 mL	1.5632 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (3.91 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (3.91 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Meinolf Lange, et al. Synthesis of oligonucleotides. WO2008141682A1.

Synonyms

Guanosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-N-(2-methyl-1-oxopropyl)-

5′-O-[Bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-N-(2-methyl-1-oxopropyl)guanosine

5′-O-(Dimethoxytrityl)-N-isobutyryldeoxyguanosine