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[CAS NO. 69123-98-4] Fialuridine
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-118122 |
| Brand: | MCE |
| CAS: | 69123-98-4 |
Overview
| MDL | MFCD00866922 |
|---|---|
| Molecular Weight | 372.09 |
| Molecular Formula | C9H10FIN2O5 |
| SMILES | O[C@H]1[C@H](F)[C@H](N2C(NC(C(I)=C2)=O)=O)O[C@@H]1CO |
Summary
Fialuridine is a nucleoside analog with antiviral activity [1] . Fialuridine shows anti-orthopoxvirus activity.
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date | Phase |
|---|---|---|---|---|
| NCT00000654 | National Institute of Allergy and Infectious Diseases (NIAID)|Oclassen Pharmaceuticals |
Herpes Simplex|HIV Infections|Hepatitis B
|
Phase 2 |
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 100 mg/mL ( 268.75 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.6875 mL | 13.4376 mL | 26.8752 mL |
| 5 mM | 0.5375 mL | 2.6875 mL | 5.3750 mL |
| 10 mM | 0.2688 mL | 1.3438 mL | 2.6875 mL |
References
- [1] Mansuri MM, et al. 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-ethyluracil. A highly selective antiherpes simplex agent. J Med Chem. 1987 May;30(5):867-71.
- [2] Mark N Prichard, et al. Orthopoxvirus targets for the development of antiviral therapies. Curr Drug Targets Infect Disord. 2005 Mar;5(1):17-28.
Synonyms
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