[CAS NO. 6915-15-7]  Malic acid

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PRODUCTS SPECIFICATIONS [6915-15-7]

Catalog
HY-Y1311
Brand
MCE
CAS
6915-15-7

DESCRIPTION [6915-15-7]

Overview

MDLMFCD00064212
Molecular Weight134.09
Molecular FormulaC4H6O5
SMILESO=C(O)C(O)CC(O)=O

For research use only. We do not sell to patients.

1 Publications Citing Use of MCE


Summary

Malic acid (Hydroxybutanedioic acid) is a dicarboxylic acid that is naturally found in fruits such as apples and pears. It plays a role in many sour or tart foods.


IC50 & Target

Human Endogenous Metabolite


Clinical Trial

NCT Number Sponsor Condition Start Date Phase
NCT04756986 Hams Hamed Abdelrahman|Alexandria University
Xerostomia
January 1, 2021 Not Applicable
NCT01652001 Universidad de Granada|Instituto de Salud Carlos III
Xerostomia|Depression|Hypertension
January 2011 Phase 2|Phase 3

Appearance

Solid



Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 745.77 mM ; Need ultrasonic)

H 2 O : 100 mg/mL ( 745.77 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.4577 mL 37.2884 mL 74.5768 mL
5 mM 1.4915 mL 7.4577 mL 14.9154 mL
10 mM 0.7458 mL 3.7288 mL 7.4577 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: PBS

    Solubility: 110 mg/mL (820.34 mM); Clear solution; Need ultrasonic

  • 2.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.08 mg/mL (15.51 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (15.51 mM); Clear solution

  • 4.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.08 mg/mL (15.51 mM); Clear solution

* All of the co-solvents are available by MCE.


Synonyms

Butanedioic acid, 2-hydroxy-
Malic acid
Butanedioic acid, hydroxy-
2-Hydroxybutanedioic acid
α-Hydroxysuccinic acid
Hydroxysuccinic acid
2-Hydroxyethane-1,2-dicarboxylic acid
Pomalus Acid
Deoxytetraric acid
2-Hydroxysuccinic acid
Musashi-no-Ringosan
Hydroxybutanedioic acid
dl-Malic acid
FDA 2018
(±)-Malic acid
DL-Malic acid
R,S(±)-Malic acid
E 296
NSC 25941
Nanoveson M
Xeros
Monohydroxybutanedioic acid
Purac Powder MA
Purac MA