[CAS NO. 7758-16-9] Sodium pyrophosphate
PRODUCTS SPECIFICATIONS [7758-16-9]
DESCRIPTION [7758-16-9]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 221.94 |
| Molecular Formula | H2Na2O7P2 |
| SMILES | [Na2H2P2O7] |
Summary
Disodium pyrophosphate (SAPP), a food additive, is an inorganic compound. Disodium pyrophosphate has potential hematotoxic and immunotoxic effects [1] .
In Vivo
Disodium pyrophosphate (oral administration, 12.6 mg/kg) displays hematotoxic and immunotoxic effects with long-term exposure in rats [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
| Animal Model: | Adult Sprague-Dawley rats [1] |
| Dosage: | 12.6 mg/kg |
| Administration: | Oral administration |
| Result: |
Displayed significant leukopenic condition.
Decreased in CD3 T-lymphocyte and CD20 Blymphocyte immunolabeling in rats. Downregulated of PPAR-α and PPAR-γ together with upregulation of TNF-α. |
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date | Phase |
|---|---|---|---|---|
| NCT04441671 | Tampere University Hospital|UMC Utrecht|Hungarian Academy of Sciences |
Pseudoxanthoma Elasticum
|
December 8, 2020 | Phase 2 |
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)