MDL | - |
---|---|
Molecular Weight | 132.17 |
Molecular Formula | C513CH13NO2 |
SMILES | CC[C@H](C)[C@H](N)[13C](O)=O |
L-Isoleucine-1-13C is the 13C-labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid [1] . L-Isoleucine is an essential amino acid.
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Solid
Room temperature in continental US; may vary elsewhere.
Powder | -20°C | 3 years |
---|---|---|
4°C | 2 years | |
In solvent | -80°C | 6 months |
-20°C | 1 month |
H 2 O : 12.5 mg/mL ( 94.58 mM ; ultrasonic and warming and heat to 60°C)
Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
---|
1 mM | 7.5660 mL | 37.8301 mL | 75.6601 mL |
5 mM | 1.5132 mL | 7.5660 mL | 15.1320 mL |
10 mM | 0.7566 mL | 3.7830 mL | 7.5660 mL |
Add each solvent one by one: PBS
Solubility: 25 mg/mL (189.15 mM); Clear solution; Need ultrasonic